Navigation Links
Bleeding Alert Sounded for Stroke Drugs
Date:3/8/2010

Medication combination raises risk 10-fold, small study finds,,,,

MONDAY, March 8 (HealthDay News) -- People treated with the clot-dissolving drug tPA for a stroke caused by a blocked brain artery are significantly more likely to have excess bleeding if they have been taking the anti-clotting drug Coumadin, even though a test shows no great danger of bleeding, new research indicates.

"In our small sample, there was a 10-fold increased risk among those taking Coumadin [warfarin]," said study author Dr. Shyam Prabhakaran, an assistant professor of neurological sciences and head of the stroke program at Rush University Medical Center in Chicago. "I think we have raised a doubt that hasn't been looked at before and should make us be sure that tPA is safe for these patients before we move forward."

Current guidelines say that tPA, or tissue plasminogen activator, should be used quickly to dissolve a clot that is blocking a brain artery -- within three hours after the first symptoms, as late as four and a half hours in some cases. But they say that the drug should be used only when a measurement called the international normalized ratio, or INR, which measures the tendency of blood to clot, is 1.7 or lower. A higher INR means a greater tendency to bleed.

The study, published online March 8 in Archives of Neurology, reported on the use of tPA in 107 people who had ischemic strokes, those caused by a blocked artery, from 2002 to 2009. Among them, the incidence of excess bleeding in the 13 people who had been taking Coumadin before the stroke was 30.2 percent, compared with 3.2 percent for those who had not been taking the drug.

Prabhakaran was quick to point out the faults in the study. "It is a single-center, retrospective study and not large enough so that it could be affected by sample size," he said. "We need a larger data set from more centers."

That information should be forthcoming now tha
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved

Page: 1 2 3

Related medicine news :

1. Genetic cause discovered for rare bleeding disorder
2. Alternative to Warfarin May Cut Risk of Bleeding
3. Endometrial Ablation Offers Relief for Abnormally Heavy or Irregular Menstrual Bleeding
4. What are the risk factors for rebleeding after negative angiography?
5. Study shows carvedilol is effective in preventing variceal bleeding in cirrhotic patients
6. Endoscopy within 24 hours shows better outcomes in elderly with peptic ulcer bleeding
7. Heart Drug Combos Raise Risk of Gastrointestinal Bleeding
8. Experts reach consensus on diagnosis and treatment of bleeding disorders in women
9. New Study Shows Women Experience Significantly Less Unscheduled Bleeding With the ORTHO TRI-CYCLEN(R) LO Birth Control Pill Versus Another Pill
10. Xanodynes New Drug Application for the Treatment of Heavy Menstrual Bleeding (Menorrhagia) Accepted for Filing with a Priority Review Classification
11. Weekend Admission May Be Riskier for GI Bleeding
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/3/2015)... Lenexa, KS (PRWEB) , ... July 03, 2015 ... ... firm dedicated exclusively to healthcare providers, has been retained to lead a national ... Okla. One of the top-ranked executive search firms in the healthcare industry, B. ...
(Date:7/3/2015)... Orange, CT (PRWEB) , ... July 03, 2015 , ... ... at home is a good blender and easily accessible, quality ingredients. Aurora Natural is ... your smoothie for an added boost of fiber, protein, antioxidants, vitamins and minerals! , ...
(Date:7/3/2015)... ... , ... Jennifer Renee Hanes, DO is the new Medical Director of its ... independent freestanding emergency rooms in the United States. , “We are excited to welcome ... Executive Medical Director of First Choice Emergency Room, Dr. James M. Muzzarelli. , ...
(Date:7/3/2015)... ... ... Selfie on a Stick ” was featured on NewsWatch as part of its monthly ... Forstrom, a technology expert and special reporter for NewsWatch, conducted the review and shared ... smartphone has an incredibly powerful camera built into it. And when someone is traveling ...
(Date:7/3/2015)... ... ... Every year, One-to-1 Fitness and the Red Deer Fit Body ... community with free fitness training and indoor fitness boot camp classes for 24 straight ... thousands of charity dollars and ended with a $10,000 donation to the Jumpstart organization. ...
Breaking Medicine News(10 mins):Health News:Jane Phillips Medical Center Retains B. E. Smith to Recruit New Chief Nursing Officer 2Health News:Jane Phillips Medical Center Retains B. E. Smith to Recruit New Chief Nursing Officer 3Health News:Aurora Product, Inc. Announces An Original New Line: Smoothie Fixins’ 2Health News:Dr. Jennifer Renee Hanes Named by First Choice Emergency Room as Medical Director of Missouri City, TX Facility 2Health News:Dr. Jennifer Renee Hanes Named by First Choice Emergency Room as Medical Director of Missouri City, TX Facility 3Health News:Learn How to Take Selfies like Kendall Jenner 2Health News:Red Deer Fitness Studio Raises $10,000 for Charity Organization with 24-Hour Train-a-Thon 2Health News:Red Deer Fitness Studio Raises $10,000 for Charity Organization with 24-Hour Train-a-Thon 3
... 28 MSA (NYSE: MSA ) today announced that net ... $293.2 million for the second quarter of 2008, a decrease of $66.0 ... 2009 was $12.5 million, or 35 cents per basic share, a decrease ... cents per basic share, for the same quarter last year. , ...
... , EAST RUTHERFORD, N.J., July 28 Cambrex Corporation (NYSE: CBM ) announced ... closes. , , The Company will host a conference call to discuss the ... Second Quarter 2009 Earnings Conference Call, ... 5, 2009 at 8:30 a.m. Eastern Time, Dial-in: ...
... experts say , TUESDAY, July 28 (HealthDay News) -- Antiviral ... elderly and should be reserved for young people, suggest researchers ... on the spread of the H1N1 virus. , If the ... drugs would not significantly reduce death rates among people older ...
... , DES PLAINES, Ill., July 28 Our ... for thousands of nurses, emergency departments are the sources of injury. ... that more than half of emergency nurses report experiencing physical violence ... shoved," "scratched," and "kicked." One in four has experienced such ...
... , , ... 28 CVS Caremark (NYSE: CVS ) announced today ... President/Chief Operating Officer of MinuteClinic, the company,s retail-based health clinic subsidiary, ... In his new roles, Dr. Sussman will be responsible for ...
... 28 On a routine day, Specialty Silicone Fabricators in ... drains, catheter systems, intravenous drug delivery devices and pacemaker leads. ... of these miniature products. Considering that silicone is a highly ... is no small achievement. , , ...
Cached Medicine News:Health News:MSA Announces Second Quarter Results 2Health News:MSA Announces Second Quarter Results 3Health News:MSA Announces Second Quarter Results 4Health News:MSA Announces Second Quarter Results 5Health News:MSA Announces Second Quarter Results 6Health News:MSA Announces Second Quarter Results 7Health News:MSA Announces Second Quarter Results 8Health News:Save Swine Flu Drugs for Younger Patients, Study Urges 2Health News:More Than Half of Emergency Department Nurses Have Been Physically Assaulted at Work, New Study Finds 2Health News:More Than Half of Emergency Department Nurses Have Been Physically Assaulted at Work, New Study Finds 3Health News:CVS Caremark Names Andrew J. Sussman, M.D., as President/Chief Operating Officer of MinuteClinic 2Health News:CVS Caremark Names Andrew J. Sussman, M.D., as President/Chief Operating Officer of MinuteClinic 3Health News:When You Make Things That Get Implanted in People, Small Things Count 2
(Date:7/3/2015)... , July 3, 2015 A ... of hypertension, diabetes and thyroid disorders in ... and a major conference dedicated to these diseases. ... Diabetes Online , Manage Hypertension Online and ... operated by EXCEMED - combine the world,s ...
(Date:7/3/2015)... Redwood Pharma AB has entered into a ... both the US and China , ... hydrogel technology in its lead chronic Dry Eye therapeutic ... technology offers many unique competitive benefits. At lower temperatures, ... low concentrations of polymer the system can be transitioned ...
(Date:7/2/2015)... CHAPEL HILL, N.C. , July 2, 2015 ... their own employees to capture critical product and ... there are many benefits to employee-based studies, it ... to leverage their own internal employees to capture ... recent study by benchmarking firm, Best Practices, LLC, ...
Breaking Medicine Technology:Combating Three Major Chronic Diseases in Latin America With Medical Education 2Redwood Pharma Licenses Novel Hydrogel Drug Delivery Technology From Broda Technologies 2Leveraging Employee Insights to Produce Cutting-Edge Market Research 2
... Mich. , June 14 Stryker Corporation ... of its manufacturing facilities have earned Leadership in Energy ... Building Council (USGBC).  LEED is an internationally recognized green ... a framework for identifying and implementing practical and measurable ...
... , June 14 Codexis, Inc. (Nasdaq: CDXS) ... Officer, received the Ernst & Young Entrepreneur Of The Year ® ... , , , ... Young LLP, the award recognizes outstanding entrepreneurs who are building and leading ...
Cached Medicine Technology:Stryker Facilities Earn LEED® Certifications 2Codexis CEO Alan Shaw Named Ernst & Young Entrepreneur Of The Year® 2010 Recipient in Northern California 2Codexis CEO Alan Shaw Named Ernst & Young Entrepreneur Of The Year® 2010 Recipient in Northern California 3
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: