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Bladder Cancer Risk Even Higher for Smokers Than Thought
Date:8/16/2011

By Serena Gordon
HealthDay Reporter

TUESDAY, Aug. 16 (HealthDay News) -- Almost half of all bladder cancers can be attributed to smoking cigarettes, and the risk of bladder cancer has increased significantly for smokers in the past three decades, a new study finds.

Smokers now face a four times higher risk of developing bladder cancer than someone who has never smoked. Thirty years ago, that risk was about three times that of never-smokers.

Even smokers who've quit the habit still face an increased risk -- 2.2 times higher -- than people who've never smoked, though the risk lessens with time.

"The best way to prevent bladder cancer is for people not to smoke," said study author Neal D. Freedman, an investigator at the National Cancer Institute. "Our study emphasizes the importance of preventing smoking initiation, or for smoking cessation for those who already smoke."

Results of the study will be published in the Aug. 17 issue of the Journal of the American Medical Association.

More than 350,000 people are diagnosed with bladder cancer each year, according to the study. More than 70,000 of those cases occur in the United States, according to the study. And, although the incidence rates for bladder cancer appear to be remaining stable, the researchers noted that findings from several studies suggested that rates for smokers seemed to be rising.

Tobacco smoking is the most significant risk factor for the development of bladder cancer, and previous estimates were that smoking increased the risk of bladder cancer nearly threefold.

To get a better idea of the current risk, Freedman and his colleagues reviewed data from the National Institutes of Health-AARP Diet and Health Study, which was conducted between 1995 and 2006. The study included 281,394 men and 186,134 women between the ages of 50 and 71. The volunteers lived in one of eight states: California, Florida, Georgia, Louisiana, M
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