Navigation Links
Bladder Cancer Risk Even Higher for Smokers Than Thought

By Serena Gordon
HealthDay Reporter

TUESDAY, Aug. 16 (HealthDay News) -- Almost half of all bladder cancers can be attributed to smoking cigarettes, and the risk of bladder cancer has increased significantly for smokers in the past three decades, a new study finds.

Smokers now face a four times higher risk of developing bladder cancer than someone who has never smoked. Thirty years ago, that risk was about three times that of never-smokers.

Even smokers who've quit the habit still face an increased risk -- 2.2 times higher -- than people who've never smoked, though the risk lessens with time.

"The best way to prevent bladder cancer is for people not to smoke," said study author Neal D. Freedman, an investigator at the National Cancer Institute. "Our study emphasizes the importance of preventing smoking initiation, or for smoking cessation for those who already smoke."

Results of the study will be published in the Aug. 17 issue of the Journal of the American Medical Association.

More than 350,000 people are diagnosed with bladder cancer each year, according to the study. More than 70,000 of those cases occur in the United States, according to the study. And, although the incidence rates for bladder cancer appear to be remaining stable, the researchers noted that findings from several studies suggested that rates for smokers seemed to be rising.

Tobacco smoking is the most significant risk factor for the development of bladder cancer, and previous estimates were that smoking increased the risk of bladder cancer nearly threefold.

To get a better idea of the current risk, Freedman and his colleagues reviewed data from the National Institutes of Health-AARP Diet and Health Study, which was conducted between 1995 and 2006. The study included 281,394 men and 186,134 women between the ages of 50 and 71. The volunteers lived in one of eight states: California, Florida, Georgia, Louisiana, Michigan, New Jersey, North Carolina and Pennsylvania.

Almost 4,000 men and 627 women were diagnosed with bladder cancer during the study.

The researchers found that current smokers now had four times the risk of developing bladder cancer compared to people who never smoked.

Overall, smoking was attributed to the development of about half of all bladder cancers.

And, the risk of bladder cancer tends to rise with the number of cigarettes smoked, according to Freedman. Even people who smoke one to 10 cigarettes a day have a significantly higher risk of bladder cancer than people who don't smoke, according to the study.

He also noted that while the risk of bladder cancer remains elevated for former smokers, it does go down the longer someone stays off cigarettes.

Freedman said the authors don't know exactly why the risk of bladder cancer has increased for smokers, but they suspect changes in the composition of cigarette smoke. Cigarettes contain less tar and nicotine now, but cigarette smoke is likely have more cancer-causing chemicals such as beta-napthylamine, which is known to cause bladder cancer, suggest the authors.

"Cigarettes may be even more toxic now than they were years ago," said Dr. Len Lichtenfeld, deputy chief medical officer for the American Cancer Society.

"People who consider themselves casual smokers may think they're not getting as many of the bad effects of smoking, but in this study, the impact of smoking increases the risk of bladder cancer dramatically," he pointed out.

Lichtenfeld advised that anyone who smokes should stop, though he acknowledged that doing so isn't easy. "Cigarettes are a very powerful addiction that's difficult to quit."

But, both experts agreed that for preventing bladder and other cancers, as well as for heart health, quitting smoking -- or never starting to smoke -- is one of the best things you can do.

More information

Learn more about bladder cancer from the National Cancer Institute.

SOURCES: Neal D. Freedman, Ph.D., M.P.H., investigator, National Cancer Institute, Rockville, Md.; Len Lichtenfeld, M.D., deputy chief medical officer, American Cancer Society, Atlanta, Ga.; Aug. 17, 2011, Journal of the American Medical Association

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Costly tests may not help detect bladder cancer recurrence, M. D. Anderson study finds
2. San Francisco Firefighters: Increased Risk for Bladder Cancer – Testing Underway
3. Meat Lovers Face Greater Risk of Bladder Cancer
4. Unmet expectations and smoking prove key factors in quitting bladder medication
5. Clue to switch of bladder cancer from locally contained to invasive found by Jefferson scientists
6. Study finds 2 sling surgeries equally effective for bladder control in women
7. Vitamins Fail to Protect Men Against Bladder Cancer
8. Radiation does not improve survival for rare, invasive bladder cancer
9. Removing Gallbladder Sooner Cuts Costs, Readmissions
10. NOSCAR announces first NOTES transoral and transvaginal gallbladder removals performed as part of US multicenter human trial
11. Certain meat components may increase bladder cancer risk
Post Your Comments:
Related Image:
Bladder Cancer Risk Even Higher for Smokers Than Thought
(Date:11/25/2015)... ... November 25, 2015 , ... "When I underwent ... bras were incredibly uncomfortable," said an inventor from Bronx, N.Y. "In order to ... the patent-pending RECOVERY BRA for added comfort and support. The bra is easier ...
(Date:11/25/2015)... ... November 25, 2015 , ... Bcureful—a non-profit organization devoted to ... raising public awareness of the disorder while helping to bring expert medical care ... to bolster progress at the Tuberous Sclerosis Complex Center at Ann & Robert ...
(Date:11/24/2015)... Florida (PRWEB) , ... November 25, 2015 , ... ... planning and monitoring. Their Care Plan software creates an agreement between the ... patient care plan, including financial, scheduling, monitoring, notification, and projections. Click ...
(Date:11/24/2015)... ... November 24, 2015 , ... Young patients with a ... Dr. Angela Wolfman and Dr. Kedar S. Lele, who are pediatric dentists in ... and fillings, the WaterLase iPlus 2.0™ system causes minimal discomfort and bleeding to the ...
(Date:11/24/2015)... ... November 25, 2015 , ... ... solutions for drugs, biologics, consumer health and global clinical supply services, today announced ... upcoming Clinical Trial Supply East Asia Conference, to be held at the InterContinental ...
Breaking Medicine News(10 mins):
(Date:11/24/2015)... Nov. 24, 2015  Thanks to a donor with ... Mary,s Medical Center,s Sister Diane Grassilli Center for Women,s ... in San Francisco . ... stepped forward with a gift of $617,320 that allowed ... Mammography with Tomosynthesis and Whole Breast Ultrasound. Tomosynthesis, three-dimensional ...
(Date:11/24/2015)... 24, 2015  Array BioPharma Inc. (Nasdaq: ... Officer, Ron Squarer , will present at ... York.  The public is welcome to participate in ... BioPharma website.Event:Piper Jaffray Annual Healthcare ConferencePresenter:  , Ron ... 2015Time:1:30 p.m. Eastern Time Webcast: , ...
(Date:11/24/2015)... and VANCOUVER, Nov. 24, 2015 /PRNewswire/ - ESSA ... EPIX ) announced today that the first patient ... of EPI-506 as a treatment for metastatic castration-resistant prostate ... and Canada.  --> the ... In the Phase 1/2 clinical trial, ESSA intends ...
Breaking Medicine Technology: