Navigation Links
Black Americans With Lupus Have Better Response to Flu Vaccine
Date:5/19/2011

THURSDAY, May 19 (HealthDay News) -- Black Americans with lupus have a higher antibody response to flu vaccination than whites with lupus, a new study says.

This may be good news for black Americans with the disease, since patients who had a weak response to the flu vaccine were more likely to experience moderate to severe disease flares following vaccination, compared to patients who had a greater response.

As many as 322,000 adults in the United States have systemic lupus erythematosus (SLE), an autoimmune disorder in which the immune system produces antibodies that attack the body's own tissues and organs. Immunosuppressive therapy and immune system problems make lupus patients more susceptible to infection, according to the researchers.

Because of this increased risk, vaccination against common infectious diseases such as the flu are recommended for lupus patients.

In this study, U.S. researchers analyzed blood samples and disease activity of 72 lupus patients and 72 healthy patients before they received a flu vaccination and two, six and 12 weeks after vaccination. Based on their antibody response to flu vaccination, the patients were categorized as either high or low responders.

Black patients were three times more likely to be high responders than whites. The researchers also found that patients taking the immunosuppressant drug prednisone (10 mg/day or more) were more likely to be low responders (67 percent) than high responders (47 percent).

A low response was also more likely among patients with a history of hemolytic anemia.

The study appears online May 19 in the journal Arthritis & Rheumatism.

"Studies investigating biomarkers that could predict which lupus patients are likely to experience a flare following vaccination are already under way," wrote lead researcher Dr. Judith James, chair of the arthritis and clinical immunology program at the Oklahoma Medical Research Foundation and professor of medicine at the University of Oklahoma Health Sciences Center, and colleagues, in a journal news release.

"This information, along with serologic tests of patients expected to mount a weak response, would help clinicians identify those SLE patients who may need an alternate vaccination schedule or would need to be closely monitored after receiving the influenza vaccine," she added.

Infectious diseases cause 23 percent of all hospitalizations and 20 percent to 50 percent of all deaths among lupus patients.

The Lupus Foundation of America has designated May as Lupus Awareness Month.

More information

The U.S. National Institute of Arthritis and Musculoskeletal and Skin Diseases has more about lupus.

-- Robert Preidt

SOURCE: Arthritis & Rheumatism, news release, May 19, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. PolicyLink CEO Angela Glover Blackwell Released the Following Statement on First Lady Michelle Obamas Childhood Obesity Initiative
2. Blacks in Nursing Homes Vaccinated Less Than Whites
3. U.S. Census Bureau Black History Month Feature for Feb. 14
4. Information Gap Could Delay Lung Cancer Therapy in Blacks
5. Genetic Mutation Linked to Prostate Cancer in Blacks
6. Black Women at Higher Risk of Birth-Related Heart Problem
7. Shortage of Black Doctors Rooted in Social, Economic Ills
8. Blacks less likely to know they have heart condition or to use treatment for it, says Mayo Clinic
9. U.S. Surgeon General Regina Benjamin to Address National Association of Black Journalists Conference on Health Disparities
10. Pyzdek Institute Releases Online Lean Six Sigma Black Belt Training
11. Blacks Less Likely to Abuse Alcohol
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Black Americans With Lupus Have Better Response to Flu Vaccine
(Date:6/26/2016)... , ... June 26, 2016 , ... ... once they have been diagnosed with endometriosis. These women need a treatment plan ... require a comprehensive approach that can help for preservation of fertility and ultimately ...
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... Austin residents ... the American College of Mohs Surgery and to Dr. Russell Peckham for medical and ... highly effective treatment for skin cancer. The selective fellowship in Mohs Micrographic Surgery completed ...
(Date:6/25/2016)... California (PRWEB) , ... June 25, 2016 , ... "With ... fit their specific project," said Christina Austin - CEO of Pixel Film Studios. ... customizable and all within Final Cut Pro X . Simply select a ProHand ...
(Date:6/25/2016)... Long Beach, CA (PRWEB) , ... June 25, 2016 , ... ... from UCLA with Magna Cum Laude and his M.D from the David Geffen School ... San Diego and returned to Los Angeles to complete his fellowship in hematology/oncology at ...
(Date:6/25/2016)... ... June 25, 2016 , ... On Friday, June 10, Van Mitchell, ... at Work award to iHire in recognition of their exemplary accomplishments in worksite health ... annual Maryland Workplace Health & Wellness Symposium at the BWI Marriott in Linthicum Heights. ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , Belgium , June ... MKT: VNRX), today announced the appointment of Dr. ... of Directors as a Non-Executive Director, effective June ... Company,s Audit, Compensation and Nominations and Governance Committees.  ... Dr. Futcher will provide independent expertise and strategic ...
(Date:6/23/2016)... June 23, 2016 Research and ... Excipients Market by Type (Organic Chemical (Sugar, Petrochemical, Glycerin), ... Topical, Coating, Parenteral) - Global Forecast to 2021" ... The global pharmaceutical excipients market is projected ... CAGR of 6.1% in the forecast period 2016 to ...
(Date:6/23/2016)... , June 23, 2016 Research ... Pharma News Issue 52" report to their offering. ... in influenza treatment creates a favourable commercial environment for MedImmune ... growing patient base that will serve to drive considerable growth ... vaccine would serve to cap sales considerably, but development is ...
Breaking Medicine Technology: