Navigation Links
Bitter Taste Receptors Found in Lungs May Aid Asthma Patients
Date:10/25/2010

SUNDAY, Oct. 24 (HealthDay News) -- Bitter taste receptors are located in the lungs as well as on the tongue, a finding that might lead to improved treatments for asthma and other obstructive lung diseases, according to researchers at the University of Maryland School of Medicine in Baltimore.

"The detection of functioning taste receptors on smooth muscle of the bronchus in the lungs was so unexpected that we were at first quite skeptical ourselves," said the study's senior author, Dr. Stephen B. Liggett, professor of medicine and physiology and director of the university's cardiopulmonary genomics program, in a university news release.

The receptors in the lungs -- which the team found by accident in an unrelated study -- are the same as those on the tongue. But the tongue's receptors are clustered in taste buds that send signals to the brain, while the receptors in the lungs are not grouped in buds and don't send signals to the brain, explained the research team. However, they still respond to bitter tastes.

The researchers tested different bitter compounds on human and mouse airways, individual airway smooth muscle cells, and on mice with asthma. They found that these compounds all opened lung airways more profoundly than current drugs.

The study appears online Oct. 24 in the journal Nature Medicine.

"New drugs to treat asthma, emphysema or chronic bronchitis are needed. This could replace or enhance what is now in use, and represents a completely new approach," said Liggett.

But, he added, simply eating bitter-tasting foods or compounds won't help people with asthma.

"Based on our research, we think that the best drugs would be chemical modifications of bitter compounds, which would be aerosolized and then inhaled into the lungs with an inhaler," he said.

The research, which is preliminary, was supported by grants from the U.S. National Heart, Lung, and Blood Institute of the National Institutes of Health.

More information

The U.S. National Heart, Lung, and Blood Institute has more about asthma.

-- Robert Preidt

SOURCE: University of Maryland Medical Center, news release, Oct. 24, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Bitrex Bitter Safety Additive Exhibiting at the Safe Kids Fair 2010; Making a Bitter Face to Learn about Poisoning Prevention
2. Bitter Melon Extract May Slow, Stop Breast Cancer
3. Bitter melon extract decreased breast cancer cell growth
4. Bitter melon extract attacks breast cancer cells
5. Salmon baby food? Babies need omega-3s and a taste for fish, scientist says
6. European Urology: Editorial about REDUCE trial underlines value of dutasteride
7. The Science Behind Musical Taste
8. Carrousel Yacht: Miami Private Yacht Charters With Style, Taste and Value
9. Bodys Response to Foods Smell, Taste Could Be Diabetes Risk Factor
10. Oral Cancer Foundation founder named Survivor Circle Award winner
11. New method is found for accurate diagnosis of gall bladder cancer, 1 of the most deadly
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Bitter Taste Receptors Found in Lungs May Aid Asthma Patients
(Date:6/27/2016)... Overland Park, KS (PRWEB) , ... June 27, 2016 , ... ... leader in retailers of Eyeglasses . , Millions of individuals in the United ... life, eyeglasses have become a way to both correct vision and make a fashion ...
(Date:6/26/2016)... , ... June 26, 2016 , ... PawPaws brand ... new product that was developed to enhance the health of felines. The formula is ... The two main herbs in the PawPaws Cat Kidney Support Supplement Soft ...
(Date:6/25/2016)... ... , ... Austin residents seeking Mohs surgery services, can now turn to Dr. ... Russell Peckham for medical and surgical dermatology. , Dr. Dorsey brings specialization to include ... in Mohs Micrographic Surgery completed by Dr. Dorsey was under the direction of Glenn ...
(Date:6/25/2016)... , ... June 25, 2016 , ... As a lifelong ... Cum Laude and his M.D from the David Geffen School of Medicine at UCLA. ... to Los Angeles to complete his fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... A recent ... that most people are unfamiliar with. The article goes on to state that individuals ... also many of these less common operations such as calf and cheek reduction. The ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... June 23, 2016 Research and ... Excipients Market by Type (Organic Chemical (Sugar, Petrochemical, Glycerin), ... Topical, Coating, Parenteral) - Global Forecast to 2021" ... The global pharmaceutical excipients market is projected ... CAGR of 6.1% in the forecast period 2016 to ...
(Date:6/23/2016)... 23, 2016 Roche (SIX: RO, ROG; OTCQX: ... its Elecsys BRAHMS PCT (procalcitonin) assay as a dedicated ... shock. With this clearance, Roche is the first IVD ... solution for sepsis risk assessment and management. ... and PCT levels in blood can aid clinicians in ...
(Date:6/23/2016)... ANGELES , June 23, 2016 ... CAPR ), a biotechnology company focused ... therapeutics, today announced that patient enrollment in its ... in Duchenne) has exceeded 50% of its 24-patient ... enrollment in the third quarter of 2016, and ...
Breaking Medicine Technology: