Navigation Links
Bitter Taste Receptors Found in Lungs May Aid Asthma Patients
Date:10/25/2010

SUNDAY, Oct. 24 (HealthDay News) -- Bitter taste receptors are located in the lungs as well as on the tongue, a finding that might lead to improved treatments for asthma and other obstructive lung diseases, according to researchers at the University of Maryland School of Medicine in Baltimore.

"The detection of functioning taste receptors on smooth muscle of the bronchus in the lungs was so unexpected that we were at first quite skeptical ourselves," said the study's senior author, Dr. Stephen B. Liggett, professor of medicine and physiology and director of the university's cardiopulmonary genomics program, in a university news release.

The receptors in the lungs -- which the team found by accident in an unrelated study -- are the same as those on the tongue. But the tongue's receptors are clustered in taste buds that send signals to the brain, while the receptors in the lungs are not grouped in buds and don't send signals to the brain, explained the research team. However, they still respond to bitter tastes.

The researchers tested different bitter compounds on human and mouse airways, individual airway smooth muscle cells, and on mice with asthma. They found that these compounds all opened lung airways more profoundly than current drugs.

The study appears online Oct. 24 in the journal Nature Medicine.

"New drugs to treat asthma, emphysema or chronic bronchitis are needed. This could replace or enhance what is now in use, and represents a completely new approach," said Liggett.

But, he added, simply eating bitter-tasting foods or compounds won't help people with asthma.

"Based on our research, we think that the best drugs would be chemical modifications of bitter compounds, which would be aerosolized and then inhaled into the lungs with an inhaler," he said.

The research, which is preliminary, was supported by grants from the U.S. National Heart, Lung, and Blood Institute of the National Institutes of Health.

More information

The U.S. National Heart, Lung, and Blood Institute has more about asthma.

-- Robert Preidt

SOURCE: University of Maryland Medical Center, news release, Oct. 24, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Bitrex Bitter Safety Additive Exhibiting at the Safe Kids Fair 2010; Making a Bitter Face to Learn about Poisoning Prevention
2. Bitter Melon Extract May Slow, Stop Breast Cancer
3. Bitter melon extract decreased breast cancer cell growth
4. Bitter melon extract attacks breast cancer cells
5. Salmon baby food? Babies need omega-3s and a taste for fish, scientist says
6. European Urology: Editorial about REDUCE trial underlines value of dutasteride
7. The Science Behind Musical Taste
8. Carrousel Yacht: Miami Private Yacht Charters With Style, Taste and Value
9. Bodys Response to Foods Smell, Taste Could Be Diabetes Risk Factor
10. Oral Cancer Foundation founder named Survivor Circle Award winner
11. New method is found for accurate diagnosis of gall bladder cancer, 1 of the most deadly
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Bitter Taste Receptors Found in Lungs May Aid Asthma Patients
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... Apple ... care services, staged a mock evacuation of the facility as part of a disaster ... Fire Department, Echo Hose EMS and Shelton City Emergency Manager, as well as the ...
(Date:10/13/2017)... , ... October 13, 2017 , ... Global Healthcare Management’s ... Alexandria Park in Milford, NJ. This free event, sponsored by Global Healthcare Management’s ... The fun run is geared towards children of all ages; it is a ...
(Date:10/13/2017)... ... October 13, 2017 , ... “The Journey: From the ... danger possible to save lost souls in the Philippines. “The Journey: From the Mountains ... a dedicated teacher of the Bible. She has taught all ages and currently teaches ...
(Date:10/12/2017)... ... October 12, 2017 , ... Planet Fitness, one of the largest and ... plans to open a flagship location in Covington, LA at 401 N. U.S. Highway ... store next to Office Depot in the Holiday Square shopping center. Its location allows ...
(Date:10/12/2017)... ... 2017 , ... Asante, a nationally recognized health system in ... existing home health joint venture through an agreement, effective October 1, 2017, to ... home health company with Asante, delivering clinically integrated care, for the past eight ...
Breaking Medicine News(10 mins):
(Date:10/10/2017)... -- NDS received FDA 510(k) clearance in May 2017 for its highly ... designed for endoscopy environments. An innovative secondary monitor solution, ZeroWire ... support the improvement of patient outcomes, procedural efficiency, and the lowering ... ... ...
(Date:10/4/2017)... 4, 2017  South Korean-based healthcare product Development Company ... "cprCUBE" on Kickstarter. The device will educate the user ... with better efficiency compared to the dated and pricey ... on efficacy of the compression for a more informed ... goal to raise $5,000. ...
(Date:10/2/2017)... 2017  Eli Lilly and Company (NYSE: ... third quarter of 2017 on Tuesday, October 24, 2017. ... day with the investment community and media to further ... call will begin at 9 a.m. Eastern time. Investors, ... webcast of the conference call through a link that ...
Breaking Medicine Technology: