Navigation Links
Bitter Taste Receptors Found in Lungs May Aid Asthma Patients
Date:10/25/2010

SUNDAY, Oct. 24 (HealthDay News) -- Bitter taste receptors are located in the lungs as well as on the tongue, a finding that might lead to improved treatments for asthma and other obstructive lung diseases, according to researchers at the University of Maryland School of Medicine in Baltimore.

"The detection of functioning taste receptors on smooth muscle of the bronchus in the lungs was so unexpected that we were at first quite skeptical ourselves," said the study's senior author, Dr. Stephen B. Liggett, professor of medicine and physiology and director of the university's cardiopulmonary genomics program, in a university news release.

The receptors in the lungs -- which the team found by accident in an unrelated study -- are the same as those on the tongue. But the tongue's receptors are clustered in taste buds that send signals to the brain, while the receptors in the lungs are not grouped in buds and don't send signals to the brain, explained the research team. However, they still respond to bitter tastes.

The researchers tested different bitter compounds on human and mouse airways, individual airway smooth muscle cells, and on mice with asthma. They found that these compounds all opened lung airways more profoundly than current drugs.

The study appears online Oct. 24 in the journal Nature Medicine.

"New drugs to treat asthma, emphysema or chronic bronchitis are needed. This could replace or enhance what is now in use, and represents a completely new approach," said Liggett.

But, he added, simply eating bitter-tasting foods or compounds won't help people with asthma.

"Based on our research, we think that the best drugs would be chemical modifications of bitter compounds, which would be aerosolized and then inhaled into the lungs with an inhaler," he said.

The research, which is preliminary, was supported by grants from the U.S. National Heart, Lung, and Blood Institute of the Nat
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Bitrex Bitter Safety Additive Exhibiting at the Safe Kids Fair 2010; Making a Bitter Face to Learn about Poisoning Prevention
2. Bitter Melon Extract May Slow, Stop Breast Cancer
3. Bitter melon extract decreased breast cancer cell growth
4. Bitter melon extract attacks breast cancer cells
5. Salmon baby food? Babies need omega-3s and a taste for fish, scientist says
6. European Urology: Editorial about REDUCE trial underlines value of dutasteride
7. The Science Behind Musical Taste
8. Carrousel Yacht: Miami Private Yacht Charters With Style, Taste and Value
9. Bodys Response to Foods Smell, Taste Could Be Diabetes Risk Factor
10. Oral Cancer Foundation founder named Survivor Circle Award winner
11. New method is found for accurate diagnosis of gall bladder cancer, 1 of the most deadly
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Bitter Taste Receptors Found in Lungs May Aid Asthma Patients
(Date:7/25/2014)... Port Washington, NY (PRWEB) July 25, 2014 ... to protecting the rights of consumers comments on a ... the widow of a smoker $23.6 billion in punitive ... which manufactures Kool brand cigarettes. The case is Cynthia ... in 2008 in the Florida First Circuit Court, Escambia ...
(Date:7/25/2014)... July 25, 2014 Hastings and ... discount attorney’s fees with regard to personal injury claims, ... a wide range of legal services for those that ... of another individual or corporation. Free initial consultation services ... validity of a potential personal injury claim . ...
(Date:7/25/2014)... July 25, 2014 (HealthDay News) -- Babies seem to ... By the time women are 34 weeks pregnant, ... their mother,s voice reciting a familiar nursery rhyme, the ... source of sensory stimulation in the developing fetus," Charlene ... of Florida,s College of Nursing, said in a university ...
(Date:7/25/2014)... of Anesthesiologists (ASA) today announced the launch of ... a national initiative designed to improve the patient ... than 40 leading health care organizations from across ... will convene for the first time at the ... Schaumburg, Ill. , The PSH collaborative participants will ...
(Date:7/25/2014)... (PRWEB) July 25, 2014 CarePoint Health ... Dr. Edward Boylan, has joined our network, CarePoint Health ... community. Hundreds of highly skilled and experienced physicians comprise ... doctors and practices in Hudson County, representing a wide ... commitment to provide the highest quality care to patients ...
Breaking Medicine News(10 mins):Health News:A Florida Jury Awards Widow More Than $23 Billion in Punitive Damages in a Lawsuit Brought Against Tobacco Maker, R.J. Reynolds, Parker Waichman LLP Comments 2Health News:A Florida Jury Awards Widow More Than $23 Billion in Punitive Damages in a Lawsuit Brought Against Tobacco Maker, R.J. Reynolds, Parker Waichman LLP Comments 3Health News:Hastings and Hastings Announces Complimentary Consultation Services 2Health News:Hastings and Hastings Announces Complimentary Consultation Services 3Health News:Rhymes Reveal Evidence of Learning in the Womb 2Health News:ASA launches national Perioperative Surgical Home learning collaborative 2Health News:ASA launches national Perioperative Surgical Home learning collaborative 3Health News:Dr. Boylan Joins CarePoint Health Medical Group 2
... Distance to care not a factor, study finds, urging greater ... News) -- Living farther away from transplant centers doesn,t explain ... apt than whites to be placed on the kidney transplant ... team that analyzed data on end-stage renal (kidney) disease patients ...
... start-ups, without forcing doctors into ... ... Corporation,today announced the pre-release of Praxis Electronic Medical Records,Version 4, featuring ... tap into the knowledge of other clinicians,enabling rapid start- ups for ...
... Nov. 9 Innovation Management Group,Inc. (IMG) announced ... 1.50, a,low cost, full screen magnification software. Most ... individuals who have extreme visual,impairments or are legally ... hundred to,several thousand dollars. The Magnifier is the ...
... at Military Bases and for Download -, PHOENIX, ... members, their families and veterans will be available,beginning Nov. ... Fighting, America Supports You, TriWest Healthcare Alliance and,many other ... "For the Troops" at 4 p.m. on,Nov. 16 at ...
... Genome Sciences,Inc. (Nasdaq: HGSI ) announced today that ... be webcast and may be accessed at, http://www.hgsi.com ... of Human Genome Sciences, senior management team will present,an ... at 4:30 pm Eastern,Time. Investors interested in listening ...
... genes associated with the Alzheimer,s ... FRESNO, Calif., Nov. 9 Consuming grapes may ... presented,this week at the Society for Neuroscience conference in ... in grapes, which,includes resveratrol, quercetin, catechins and other phytonutrients, ...
Cached Medicine News:Health News:Blacks in Poor Areas Less Likely to Be On Kidney Transplant Lists 2Health News:Infor-Med, Inc. Announces New Praxis EMR Version 4 with The Praxis Knowledge Exchanger(R) 2Health News:IMG Announces an Affordable Full Screen Software Magnifier for Home and Business Users 2Health News:TriWest, Grammy-Nominated Artist and Partners Release 'For the Troops' CD in Appreciation of Military Members 2Health News:TriWest, Grammy-Nominated Artist and Partners Release 'For the Troops' CD in Appreciation of Military Members 3Health News:Eating Grapes May Protect Against Alzheimer's Disease 2
(Date:7/25/2014)... 25, 2014 Leading events organizer UBM ... for the seventh year to São Paulo, Brazil ... August 2014. The event will co-locate with Food Ingredients South ... comprehensive meeting point for the pharmaceutical industry.      ... for pharmaceutical sales are now exploring the South ...
(Date:7/25/2014)... -- Arena Pharmaceuticals, Inc. (NASDAQ: ARNA ) today ... second quarter 2014 financial results before the NASDAQ Global ... same day, Arena will host a conference call and ... Time). The conference call may be ... for international callers. Please specify to the operator that ...
(Date:7/24/2014)... Calif. , July 24, 2014   AcelRx ... pharmaceutical company focused on the development and commercialization of ... pain, today confirmed the PDUFA date for Zalviso remains ... that a rumor circulated online stating the Food and ... 24, 2014 there has been no notification to the ...
Breaking Medicine Technology:CPhI South America 2014 Launches with Generics Showing Huge Growth 2CPhI South America 2014 Launches with Generics Showing Huge Growth 3CPhI South America 2014 Launches with Generics Showing Huge Growth 4Arena Pharmaceuticals to Host Corporate Update and Financial Results Conference Call and Webcast on Friday, August 1 2Arena Pharmaceuticals to Host Corporate Update and Financial Results Conference Call and Webcast on Friday, August 1 3AcelRx Pharmaceuticals Confirms July 27, 2014 PDUFA Date for Zalviso 2
... The Clariflex® Intraocular Lens is indicated ... years of age or older in whom ... IOL is a third-generation IOL design made ... is designed both to reduce internal reflections ...
... Chamber Lenses: The Bausch & Lomb PMMA Posterior ... for primary implantation for the visual correction of ... older where a cataractous lens has been removed ... to be placed in the ciliary sulcus or ...
... All USIOL lenses are manufactured ... and processes. Perspex CQ UV ... the multi-piece and single piece ... available in both nonphaco and ...
... sterile nonpyrogenic, transparent viscoelastic solution of highly ... mg/ml of high molecular weight (greater than ... physiological saline. In the limit of zero ... (105 Pa s) at 25 C and ...
Medicine Products: