Navigation Links
Bitter Taste Receptors Found in Lungs May Aid Asthma Patients
Date:10/25/2010

SUNDAY, Oct. 24 (HealthDay News) -- Bitter taste receptors are located in the lungs as well as on the tongue, a finding that might lead to improved treatments for asthma and other obstructive lung diseases, according to researchers at the University of Maryland School of Medicine in Baltimore.

"The detection of functioning taste receptors on smooth muscle of the bronchus in the lungs was so unexpected that we were at first quite skeptical ourselves," said the study's senior author, Dr. Stephen B. Liggett, professor of medicine and physiology and director of the university's cardiopulmonary genomics program, in a university news release.

The receptors in the lungs -- which the team found by accident in an unrelated study -- are the same as those on the tongue. But the tongue's receptors are clustered in taste buds that send signals to the brain, while the receptors in the lungs are not grouped in buds and don't send signals to the brain, explained the research team. However, they still respond to bitter tastes.

The researchers tested different bitter compounds on human and mouse airways, individual airway smooth muscle cells, and on mice with asthma. They found that these compounds all opened lung airways more profoundly than current drugs.

The study appears online Oct. 24 in the journal Nature Medicine.

"New drugs to treat asthma, emphysema or chronic bronchitis are needed. This could replace or enhance what is now in use, and represents a completely new approach," said Liggett.

But, he added, simply eating bitter-tasting foods or compounds won't help people with asthma.

"Based on our research, we think that the best drugs would be chemical modifications of bitter compounds, which would be aerosolized and then inhaled into the lungs with an inhaler," he said.

The research, which is preliminary, was supported by grants from the U.S. National Heart, Lung, and Blood Institute of the Nat
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Bitrex Bitter Safety Additive Exhibiting at the Safe Kids Fair 2010; Making a Bitter Face to Learn about Poisoning Prevention
2. Bitter Melon Extract May Slow, Stop Breast Cancer
3. Bitter melon extract decreased breast cancer cell growth
4. Bitter melon extract attacks breast cancer cells
5. Salmon baby food? Babies need omega-3s and a taste for fish, scientist says
6. European Urology: Editorial about REDUCE trial underlines value of dutasteride
7. The Science Behind Musical Taste
8. Carrousel Yacht: Miami Private Yacht Charters With Style, Taste and Value
9. Bodys Response to Foods Smell, Taste Could Be Diabetes Risk Factor
10. Oral Cancer Foundation founder named Survivor Circle Award winner
11. New method is found for accurate diagnosis of gall bladder cancer, 1 of the most deadly
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Bitter Taste Receptors Found in Lungs May Aid Asthma Patients
(Date:4/23/2014)... April 24, 2014 Pregnant immigrants from Sub-Saharan ... increased monitoring during pregnancy, according to new research ... today in the British Journal of Obstetrics ... and eclampsia rates among immigrants and native-born women ... (Ontario), Denmark, Sweden, Spain (Catalonia and Valencia) and ...
(Date:4/23/2014)... The American Society for Radiation Oncology (ASTRO) has ... Radiation Therapy for Endometrial Cancer: An ASTRO Evidence-Based ... therapy in the treatment of endometrial cancer. The ... 2014 issue of Practical Radiation Oncology ... The full-length guideline is available as an open-access ...
(Date:4/23/2014)... the gastro-intestinal tract has long been considered to be ... Sahlgrenska Academy have used refined microscopic techniques that indicate ... of the gastro-intestinal tract is only as large as ... The digestive tract, which passes from the mouth through ... length of about 5 meters in a normal adult, ...
(Date:4/23/2014)... of probiotics, antioxidants and other nutritional compounds, more and ... is getting in on the action. But legitimate skepticism ... industry is responding with clinical research to shore up ... Chemical & Engineering News (C&EN), the weekly news ... Bomgardner, a senior editor at C&EN, writes that about ...
(Date:4/23/2014)... Parents and physicians concerned about an increase in adolescents, ... breathe a sigh of relief. According to a new ... worth of data from states with and without medical ... increased use among adolescents. The study is published online ... Adolescent Health . , "Any time a state ...
Breaking Medicine News(10 mins):Health News:Pregnancy complications may be more common in immigrants from certain regions 2Health News:ASTRO issues guideline on the role of postoperative radiation therapy for endometrial cancer 2Health News:ASTRO issues guideline on the role of postoperative radiation therapy for endometrial cancer 3Health News:The surface area of the digestive tract 'only' as large as a studio apartment 2Health News:RI Hospital physician: Legalizing medical marijuana doesn't increase use among adolescents 2
... nitrogen-containing bisphosphonate (N-BP) cancer drugs, used to relieve bone ... has been almost entirely unknown. Researchers writing in BioMed ... used ,barcoded, yeast mutants to identify new biological processes ... opportunities for the development of new anticancer drugs. ...
... LOS ANGELES, Sept. 9 In commemoration of the first ... Red Cross of Greater Los Angeles will host three 2-hour volunteer orientations ... volunteers will receive a tour of the chapter,s new state of the ... Cross, response to the recent California wildfires. , , ...
... WASHINGTON, Sept. 9 Congressman Chaka Fattah (D-PA), a strong ... conclusion of President Obama,s address tonight to Congress and the nation: ... The time to act is now. We have been talking and ... of this 111th Congress. The American people have already voted: In ...
... , INDIANAPOLIS, Sept. 9 WellPoint, Inc. (NYSE: ... Medicare Advantage and 2010 Medicare Part D health benefit plans effective Oct. ... Medicare Part D health benefit plans on Nov. 15, 2009 for the ... Medicare and Medicaid Services (CMS) has determined that WellPoint has corrected deficiencies ...
... , DENVER, Sept. 9 DaVita Inc. (NYSE: ... for those diagnosed with chronic kidney disease (CKD), supports dialysis patients, ... standards and social circumstances. , , (Logo: http://www.newscom.com/cgi-bin/prnh/20020729/DAVITALOGO ... your everyday student at Hollywood High School in Los Angeles, CA ...
... infection known as Trichomonas vaginalis is associated ... study published online September 9 in the Journal ... Stark, ScD, of the department of epidemiology at the ... conducted a case-control study nested within the Physicians, Health ...
Cached Medicine News:Health News:Red Cross Participates in September 11th National Day of Service and Remembrance 2Health News:Statement on WellPoint's Re-Entry into Medicare Market 2Health News:DaVita's Patient-Centric Modalities Offer Students with Kidney Disease More Choices 2Health News:JNCI news brief: STD confirmed to be associated with increased risk of prostate cancer 2
(Date:1/15/2014)...  Celsion Corporation (the "Company") (NASDAQ: CLSN ) ... investors to purchase an aggregate of approximately $15 million ... direct offering, led by a dedicated health care fund. ... with these investors pursuant to which the Company agreed ...
(Date:1/15/2014)... WORTH, Texas , Jan. 15, 2014  Humberto C. ... Dermatology Achievement Award" from the Journal of Drugs ... Aesthetic & Clinical Conference (ODAC). The event is January 17-20, ... Florida . The ODAC ...
(Date:1/15/2014)... GARDENS, Fla. , Jan. 15, 2014  In an unprecedented effort ... and TB in ambulances and other transport vehicles, an advanced and ... by rescue personnel for the first time. In ... contact with these deadly pathogens, West Palm Beach ...
Breaking Medicine Technology:Celsion Corporation Announces $15 Million At-The-Market Registered Direct Offering 2Celsion Corporation Announces $15 Million At-The-Market Registered Direct Offering 3Galderma's global leader honored with a "Lifetime in Dermatology Achievement Award" by Journal of Drugs in Dermatology 2Galderma's global leader honored with a "Lifetime in Dermatology Achievement Award" by Journal of Drugs in Dermatology 3Galderma's global leader honored with a "Lifetime in Dermatology Achievement Award" by Journal of Drugs in Dermatology 4Superbugs No Longer Ride In Rescue Vehicles 2
... Sept. 26, 2011 Luminex Corporation (NASDAQ: ... xMAP Europe 2011, its annual European multiplexing technology symposium, ... The event will feature scientific sessions, workshops, discussion groups, ... around the world who are performing groundbreaking work in ...
... Sept. 26, 2011 Safely storing prescription medications ... other prescription holders. Now, an innovative new device ... dangerous medications—in a small, convenient and more portable ... Developed by CAP-N-LOCK, LLC., The ...
Cached Medicine Technology:Luminex Corporation Hosts Ninth Annual Planet xMAP Europe in Vienna 2Luminex Corporation Hosts Ninth Annual Planet xMAP Europe in Vienna 3Luminex Corporation Hosts Ninth Annual Planet xMAP Europe in Vienna 4New Combination Locking Cap Designed to Protect Children and Teens From Prescription Medications 2
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: