Navigation Links
Bitplane Webinar Highlights Recent Developments in Alzheimer’s Disease Therapy
Date:6/3/2015

Yorba Linda, CA (PRWEB) June 03, 2015

Alzheimer’s disease (AD) is the most common form of dementia with nearly 44 million people affected worldwide. Characteristic neuropathological hallmarks of the disease are ß-amyloid plaques which result from abnormal protein aggregation and deposition of ß-amyloid peptide (Aß). Aß is produced by cleavage of the amyloid precursor protein. The amyloid-cascade-hypothesis postulates, based on strong genetic evidence, that Aß accumulation is the central event in the etiology of Alzheimer’s disease.

Bitplane, an Oxford Instruments company, is sponsoring a new, free educational webinar, “The dynamics of ß-amyloid plaque genesis – an in vivo study in transgenic mice of Alzheimer’s disease,” which will present recent developments in Alzheimer’s disease therapy, particularly in the field of ß-amyloid plaque genesis and growth. There will also be a presentation of new methods of testing efficacy of Alzheimer’s therapies in preclinical studies.

The speakers will be Steffen Burgold and Finn Peters from the German Center for Neurodegenerative Diseases. They will discuss the use of long-term in vivo two-photon imaging to investigate the dynamics of ß-amyloid plaque genesis and growth in transgenic mouse models of Alzheimer’s disease. The results from the study in mice showed sigmoid-shaped growth kinetics similar to those found in humans with a familiar record of Alzheimer’s disease by applying a ß-amyloid radioactive tracer in combination with positron emission tomography imaging. The hope is that this work will help in the testing of therapeutic strategies for Alzheimer’s disease in animal models and translating them to the human situation.

Steffen Burgold is a postdoctoral researcher with a strong focus on imaging technology and its applications at the department for translational brain research of the German Center for Neurodegenerative diseases (DZNE) in Munich, Germany. During his PhD studies Dr. Burgold established a workflow to study the growth kinetics and genesis of ß-amyloid plaques in the laboratory of Prof. Dr. Jochen Herms by applying long-term in vivo two-photon microscopy in combination with advanced image analysis procedures. This work is currently applied in preclinical studies to investigate the efficacy of therapeutic strategies to treat Alzheimer’s disease.

Finn Peters is a German Biochemist with a strong focus on neuroscience and neurodegenerative diseases. Mr. Peters applies chronic in vivo two-photon microscopy to investigate the pathological mechanisms underlying Alzheimer´s disease. For this purpose he uses Imaris-assisted three-dimensional reconstruction of amyloid-beta plaques by surface rendering and develops Matlab-assisted routines for the semi-automatic quantification. This work facilitates the precision and evaluation time to assess the in vivo potency of novel drug candidates for the potential treatment of Alzheimer´s disease.

A live question-and-answer session will follow the presentation.

The complementary webinar, hosted by LabRoots, will be presented on June 11, 2015, at 7 am PT.

For full details and free registration, click here.

About Bitplane:
Bitplane is the world’s leading Interactive Microscopy Image analysis software company. Bitplane was founded in 1992 and serves customers in 29 countries with direct representation and through partner organizations. Worldwide there are over 2000 research sites with more than 10,000 active users using Imaris routinely, resulting in a large number of peer-reviewed scientific publications primarily in the field of Neurosciences, Cell Biology, Immunology and Developmental Biology. Through constant innovation and a clear focus on 3D and 4D image visualisation, analysis and interpretation, Bitplane actively shapes the way scientists process microscopy images. In 2009, Bitplane joined Andor Technology, a world leader in scientific imaging, spectroscopy solutions and microscopy systems.

About LabRoots:
LabRoots is the leading professional networking website designed to connect all science verticals. Founded in March 2008, LabRoots’ vision was to connect the scientific world leveraging a myriad of unique features and tools, discovering meaningful collaborations across geographic boundaries and fields of expertise. LabRoots is the owner and producer of BioConference Live – which has grown into the world’s largest series of virtual events within the Life Sciences and Clinical Diagnostics community.

Read the full story at http://www.prweb.com/releases/2015/06/prweb12766561.htm.


'/>"/>
Source: PRWeb
Copyright©2015 Vocus, Inc.
All rights reserved

Related medicine news :

1. Complimentary Webinar: Volvo, MAPFRE and Award Winning Start-Up discuss new Frontier of In-Car Services
2. PeopleKeys to Air a Follow-up to Their Popular DISC Trainer’s Toolbox Webinar, Featuring All-New Content and Strategies
3. FDAnews Announces — Medical Device Cybersecurity Quality Assurance: Requirements, Best Practices and Innovative Approaches Webinar, June 23, 2015
4. FDAnews Announces — Success Strategies for Biosimilars Approval: A Roadmap to the 351(k) Application Process Webinar, June 23, 2015
5. Career Step and HRS Hosting June 4 ICD10monitor Webinar on the Importance of Auditing and Physician Training for ICD-10 Success
6. Eppendorf Webinar Shows How Consumables Can Impact Outcomes in Life Science Research
7. Beckman Coulter Webinar Discusses Quantitative Determination of Reaction Stoichiometry, Interaction Energies, and Solute Masses for Sedimentation Analysis
8. Health Advocate Webinar Features Innovative Chronic Disease Management Solution
9. TABS Group to Present Results from 8th Annual Vitamin and Sports Nutrition Study during May 20th Webinar
10. Boeing’s Direct-to-Employee Benefits Model to be Featured in Upcoming AIS Webinar
11. FDAnews Announces — HCT/P Donor Compliance Risks: Best Practices for Testing, Screening and Determining Eligibility Webinar, May 28, 2015
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/19/2019)... ... 19, 2019 , ... Conducting Advanced Root Cause Analysis CAPA ... FDAnews and Learning Plus**, Mar. 26-27, 2019 – Princeton, NJ, http://www.fdanews.com/capapc ... Feb. 26. , The greatest threat to compliance is ... overconfidence. , ...
(Date:2/19/2019)... Texarkana, TX (PRWEB) , ... February 19, 2019 ... ... has announced that he is welcoming new patients with or without a referral ... a dual board-certified periodontist and prosthodontist, Dr. Kovacs routinely places All-on-4® dental ...
(Date:2/19/2019)... , ... February 19, 2019 , ... ... , “Nova Filtration is based in The Villages FL proudly serving over 3,500 ... new franchised Territory in the greater Jacksonville area selling and installing our popular ...
(Date:2/19/2019)... LOUIS (PRWEB) , ... February 19, 2019 , ... ... health system needs to improve care outcomes and patient experiences. Through the ... strategic journeys and audiences in key areas: , 1. Access Manager enhances ...
(Date:2/19/2019)... , ... February 19, 2019 , ... ... cancer survivor and well-respected advocate for patient engagement, will deliver the luncheon ... deBronkart brings critical awareness of participatory medicine and empowering partnerships between patients and ...
Breaking Medicine News(10 mins):
(Date:2/19/2019)... ... February 19, 2019 , ... The American Academy of Thermology ... training and clinical application of medical infrared imaging, has announced details for its 2019 ... Emory University Conference Center in Atlanta, GA. , This is the first year ...
(Date:2/17/2019)... ... ... Wendy B. Libby, Ph.D., today announced her decision to retire as president of ... became Stetson’s ninth president in July 2009 and its first female president since the ... of an institution as fine as Stetson University,” Libby said in announcing her decision ...
(Date:2/16/2019)... ... February 15, 2019 , ... ... treatment and LAPIP™ protocol for ailing dental implants to the Northridge and surrounding ... a growing population of dentists looking to provide their patients with top-tier care ...
Breaking Medicine Technology: