Navigation Links
Bisphenol A is affecting us at much lower doses than previously thought
Date:11/7/2013

Bisphenol A (BPA) is a known endocrine disruptor that hijacks the normal responses of hormones. Yet, traditional toxicology studies indicate that only very high doses of this chemical affect exposed animalsdoses as high as 50 mg/kg/day. For the past decade, scientists have used modern scientific techniques to probe the effects of BPA on numerous endpoints that are not examined in those traditional toxicology studies. Examining these non-traditional endpoints reveal a very different story. Because of increased understanding of the mechanisms by which hormones and chemicals that mimic hormones work, it has recently become clear that endocrine disruptors need to be studied at much lower doses.

As a consequence of this new understanding, a group of scientists that study endocrine disruption worked together to update and refine a 2007 review of the low dose effects of BPA. The group not only added hundreds of more recent studies, but they also used an integrative biological approach to scrutinize low dose effects of BPA at multiple levels of biological organization: on cells, animals and human populations.

The findings are striking. When looking at the "low dose" literature as a whole, reproducible effects were seen in animals after exposure to incredibly low doses of BPA. In fact, effective doses were ten to forty times lower than the doses identified in traditional toxicology studies. Several dozen "low dose" studies show effects of BPA at doses that humans are thought to encounter in their everyday lives.

These scientists detail in their article the effects of BPA exposure both in vitro and in vivo, and how it contributes to a large range of health problems in humans, such as polycystic ovarian syndrome, immune response to allergens, behavioral problems and decreased fertility. The effects on wildlife are also widespread.

With the knowledge that such tiny amounts of BPA can have such far-reaching implications for humans and wildlife, stricter regulations of this chemical and other endocrine disruptors should be fast on its heels.


'/>"/>

Contact: Andrew Thompson
andrew@landesbioscience.com
Landes Bioscience
Source:Eurekalert

Related medicine news :

1. Harmful effects of bisphenol A proved experimentally
2. HPV strains affecting African-American women differ from vaccines
3. According to the United Health Foundation, The Burden of Diabetes in Missouri is on the Rise, Affecting Over Ten Percent of Residents
4. Southwestern Ear, Nose & Throat Associates Offers Guidelines On Hearing Loss, Lack of Sleep Affecting Back-to-School Health
5. American Medical Association Defines Obesity as a Disease Affecting 90 Million Americans
6. Buckfire & Buckfire Motorcycle Attorney Meets with Legislators on Issues Affecting Injured Motorcyclists
7. Bipolar Disorder Drugs May Tweak Genes Affecting Brain
8. More Drug Trials Needed for Conditions Affecting Kids: Review
9. Asthma Cases Continue to Rise in U.S., Affecting Millions
10. A New Article Releases 11 “Must Know” Home Remedies to Lower High Blood Pressure – V kool
11. J&J to Pay $2.2B to Settle Allegations Over Its Marketing of Risperdal; Parker Waichman LLP Applauds Efforts of Whistleblowers in Helping Compel Resolution
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/28/2017)... ... March 28, 2017 , ... Thank you to all who attended Capio ... , This event was exclusive to providers and offered an opportunity to collaborate and ... at the Manchester Grand Hyatt where attendees gathered for a lively discussion on trends ...
(Date:3/28/2017)... , ... March 28, 2017 , ... “A Prophets Bones”: a thrilling adventure that reveals ... Quinn. , “There were things that his parents and teachers had asked of him that ... that he was going to defy the Almighty Creator. There were some who would have ...
(Date:3/27/2017)... ... March 27, 2017 , ... New patients who have sleep ... apnea treatment, with or without a referral. Sleep apnea is often left untreated because ... sleepiness, morning headaches and chronic snoring. , Dr. Braasch seeks to raise awareness ...
(Date:3/27/2017)... Claire, WI (PRWEB) , ... March 27, 2017 ... ... accepting new patients for custom smile makeovers without requiring a referral. ... including orthodontics, gum disease treatment, cosmetic dentistry and dental implants. Whether patients have ...
(Date:3/27/2017)... ... 2017 , ... Drs. Justin Kolnick, Kara Diamond, Randall Barton, Keith Hope and ... key role this treatment plays in protecting oral health, along with the benefits of ... who need a root canal in White Plains, NY or their second location in ...
Breaking Medicine News(10 mins):
(Date:3/27/2017)... CHICAGO , March 27, 2017  A ... Educators (AADE) found that Medicare,s Competitive Bidding Program (CBP) ... diabetes testing supplies. The lack of choice forces beneficiaries ... can have dire health consequences. AADE,s ... reports by AADE and others pointing out the inherent ...
(Date:3/27/2017)... 2017 FinancialBuzz.com News Commentary  ... Based on New Frontier Data,s sales ... cannabis is legal will generate $655 million in taxes on retail ... specific taxes, such as Washington State,s 37% ... from state sales taxes that are applied on all retail sales. ...
(Date:3/27/2017)... , March 27, 2017 BioLineRx Ltd. ... immunology, announced today that AGI-134, an immunotherapy for the treatment ... Agalimmune Ltd., will be featured at the upcoming American ... Washington, DC to be held on April ... ...
Breaking Medicine Technology: