Navigation Links
Birth order linked to increased risk of diabetes, metabolic disorders
Date:2/11/2013

Chevy Chase, MD Long a source of sibling rivalry, birth order may raise the risk of first-born children developing diabetes or high blood pressure, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).

First-born children have greater difficulty absorbing sugars into the body and have higher daytime blood pressure than children who have older siblings, according to the study conducted at the University of Auckland's Liggins Institute in New Zealand. The study was the first to document a 21 percent drop in insulin sensitivity among first-born children.

"Although birth order alone is not a predictor of metabolic or cardiovascular disease, being the first-born child in a family can contribute to a person's overall risk," said Wayne Cutfield, MBChB, DCH, FRACP, of the University of Auckland.

With family size shrinking in many countries, a larger proportion of the population is made up of first-born children who could develop conditions like type 2 diabetes, coronary artery disease, stroke and hypertension. The research findings may have significant public health implications for nations like China, where the one-child policy has led to a greater segment of the population being composed of first-born children.

The study measured fasting lipid and hormonal profiles, height, weight and body composition in 85 healthy children between the ages of 4 and 11. The 32 first-born children who participated in the study had a 21 percent reduction in insulin sensitivity and a 4 mmHg increase in blood pressure.

The good news for oldest and only children? The study found they tended to be taller and slimmer than their later-born counterparts, even after the height and body mass index of their parents was taken into account.

The metabolic differences in younger siblings might be caused by physical changes in the mother's uterus during her first pregnancy. As a result of the changes, nutrient flow to the fetus tends to increase during subsequent pregnancies.

For this study, researchers focused on children because puberty and adult lifestyle can affect insulin sensitivity.

"Our results indicate first-born children have these risk factors, but more research is needed to determine how that translates into adult cases of diabetes, hypertension and other conditions," Cutfield said.

Other researchers working on the study include: A. Ayyavoo, T. Savage, J. Derraik and P. Hofman of the University of Auckland.

The article, "First-born Children Have Reduced Insulin Sensitivity And Higher Daytime Blood Pressure Compared To Later-born Children," appears in the March 2013 issue of JCEM.


'/>"/>

Contact: Jenni Glenn Gingery
jgingery@endo-society.org
301-941-0240
The Endocrine Society
Source:Eurekalert

Related medicine news :

1. Depo-Provera Birth Control Might Raise Breast Cancer Risk
2. Wellesley study shows income inequality a key factor in high US teen births
3. Planning Pregnancy May Cut Birth Defects
4. U.S. Teen Births Hit Record Low
5. Certain Birth Control Pills May Carry Higher Blood Clot Risk: FDA
6. New global report says US lags behind 130 other nations in preterm birth rate
7. Pneumonia and preterm birth complications are the leading causes of childhood death
8. Babies susceptibility to colds linked to immune response at birth
9. Birth Control Pills, HRT Tied to Digestive Ills
10. Fewer Stillbirths Among Pregnant Women Vaccinated Against Flu
11. Immigrant women giving birth in Spain suffer great stress, a study warns
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... ... June 27, 2016 , ... Quality metrics are proliferating in cancer care, ... remain in the eye of the beholder, according to experts who offered insights and ... Journal of Managed Care. For the full issue, click here . , For ...
(Date:6/26/2016)... Lake Orion, Clarkston, Michigan (PRWEB) , ... June ... ... direction with respect to fertility once they have been diagnosed with endometriosis. These ... tolerable intercourse but they also require a comprehensive approach that can help for ...
(Date:6/25/2016)... ... ... First Choice Emergency Room , the largest network of independent freestanding ... of its new Mesquite-Samuell Farm facility. , “We are pleased to announce Dr. ... James M. Muzzarelli, Executive Medical Director of First Choice Emergency Room. , Dr. ...
(Date:6/24/2016)... ... ... A recent article published June 14 on E Online details ... to state that individuals are now more comfortable seeking to undergo not only the ... and cheek reduction. The Los Angeles area medical group, Beverly Hills Physicians (BHP) notes ...
(Date:6/24/2016)... ... June 24, 2016 , ... Global law firm Greenberg Traurig, P.A. announced that ... chosen by their peers for this recognition are considered among the top 2 percent ... special honors as members of this year’s Legal Elite Hall of Fame: Miami ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016  In a startling report released ... failing their residents by lacking a comprehensive, proven plan to eliminate ... a definitive ranking of how states are tackling the worst drug ... only four states – Kentucky , ... Vermont . Of the 28 failing states, three – ...
(Date:6/23/2016)... June 23, 2016 Capricor ... ), a biotechnology company focused on the discovery, ... that patient enrollment in its ongoing randomized HOPE-Duchenne ... exceeded 50% of its 24-patient target. Capricor expects ... third quarter of 2016, and to report top ...
(Date:6/23/2016)... , June 23, 2016 , ... on Thursday, July 7, 2016 , , , , LOCATION: ... , , , , EXPERT PANELISTS:  , , , ... Senior Industry Analyst, Christi Bird; Senior Industry Analyst, Divyaa Ravishankar and ... The global pharmaceutical industry is witnessing an exceptional era. ...
Breaking Medicine Technology: