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Birth cohort screening for hepatitis C is cost effective, could save thousands of lives each year
Date:11/4/2011

screening with standard treatment for patients identified with hepatitis C genotype 2 or 3, and standard treatment plus a direct acting antiviral drug (DAA) for patients identified with genotype 1 disease (the most prevalent genotype in the U.S.).

The researchers found that compared to the current strategy of risk-based screening, birth cohort screening followed by standard treatment reduced deaths by 82,300 at a cost of $15,700 per quality adjusted life-year (QALY) gained. Incorporating DAA treatment to standard therapy when indicated would prevent approximately 121,000 deaths compared to risk-based screening at a cost of $35,000 per QALY gained.

"The important things to remember about birth cohort screening are that, first, the strategy would identify over 800,000 people with hepatitis C if it were fully implemented, and second, the strategy is at least as cost-effective as many routinely administered preventive practices such as breast cancer screening or colorectal screening," said David Rein, PhD, Principal Research Scientist, Public Health Research Department, NORC at the University of Chicago, and lead author of the study.


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Contact: Angela Collom
acollom@acponline.org
215-351-2653
American College of Physicians
Source:Eurekalert

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