Navigation Links
Biosensor chip enables high-sensitivity protein analysis for disease diagnosis
Date:4/22/2010

In the battle against cancer and other diseases, precise analysis of specific proteins can point the way toward targeted treatments. Scientists at theTechnische Universitaet Muenchen (TUM), together with Fujitsu Laboratories of Japan, have developed a novel biosensor chip that not only recognizes proteins that are characteristic for specific diseases, but also can show if these proteins are changed through the influence of disease or drugs.

The human immune system recognizes pathogens by specific proteins on their surfaces. This detection principle manifests itself again and again in biology, and it is already used in medical tests. Such tests typically require relatively large amounts of sample material, however, and many problems can't be investigated in this way. For some tests, the target protein must be chemically modified by reagents. That requires both time and well trained lab technicians. Now scientists at TUM's Walter Schottky Institute have developed a biosensor one hundred times more sensitive than currently available tests in recognizing proteins that are characteristic for the clinical picture of specific diseases.

The biosensor chip holds synthetic DNA molecules, which are negatively charged, in an aqueous salt solution. These long molecules are tethered at one end to a gold surface. The free end is labeled with a fluorescent marker, so it can be optically observed; and at the very tip the scientists can place a "capture probe," a molecule that fits together with the target protein like the key to a lock. Alternating electric potentials set the DNA molecules in motion, swinging back and forth between "standing" and "lying" states with regular changes in a tightly confined but intense field. If the protein of interest is present in sample material placed on the biosensor chip, it will bind to the "key" molecule. And because this makes the DNA strands considerably heavier, their swinging motion will be noticeably slower. Preci
'/>"/>

Contact: Andreas Battenberg
battenberg@zv.tum.de
49-892-891-0510
Technische Universitaet Muenchen
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. TrackWise(R) Electronic Regulatory Reporting Solution Enables Companies to Meet Current and Future Mandates
2. New Fun Xercise Bike Enables You to Work Out and Play
3. New Breast MRI Technology Enables Enhanced Breast Cancer Detection
4. Acuo Technologies Announces a New Offering That Enables Sharing of Imaging Studies Securely and Affordably
5. Service-oriented ecosystem enables low cost devices to form interactive web of objects
6. Web Content Management Enables Government Transparency, Participation, and Collaboration Online
7. Promega - TOP srl Agreement Enables Live Animal Imaging for Cancer Studies
8. Versiera Enables Cloud and Enterprise Network Visualization
9. CradlePoint Connectivity Enables HealthCare Professionals to Enhance In-Home Patient Care
10. Scientists ID a protein that splices and dices genes
11. 3 brain diseases linked by toxic form of same neural protein
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Biosensor chip enables high-sensitivity protein analysis for disease diagnosis
(Date:12/25/2014)... 2014 Product liability lawsuits filed in ... ( http://www.consumerinjurylawyers.com/DePuy/ ) continue to move forward in federal ... issued in the U.S. District Court, Northern District of ... open conference on January 7, 2015, at the Paul ... West Palm Beach, Florida. The Conference is scheduled to ...
(Date:12/25/2014)... (PRWEB) December 26, 2014 Recently, iFitDress.com, the ... for women, has announced its new selection of black ... are on sale now; they are available at discounted prices, ... says, “The promotion will last for three weeks only. You ... market. Those who are interested in our new items can ...
(Date:12/25/2014)... (PRWEB) December 25, 2014 The short film ... was created in honor of a true 9/11 hero, Welles ... film festivals including the 24 hours of Nuremberg International Short ... Bangladesh. , Actress, screenwriter and director Luciana Lagana ... this film together with her husband, Gregory Graham ...
(Date:12/25/2014)... BambooFlooringChina.com sells many bamboo products and the business ... company announces big discounts on its bamboo mats ... BambooFlooringChina.com is the world’s leader in bamboo flooring. According ... Jan. 20, 2015. , The bamboo mats are made ... thread. All the bamboo strips for the mats are ...
(Date:12/25/2014)... 25, 2014 When head lice hits a ... a frenzy to get rid of it while keeping it ... Coral Gables now have the solution right in their neighborhood: ... location, Lice Troopers provides full spectrum head lice screening and ... area, including Sunset, Key Biscayne, Brickell, Coconut Grove, Kendall, Pinecrest ...
Breaking Medicine News(10 mins):Health News:Federal Court Overseeing DePuy ASR Hip Lawsuit Set to Convene Conference in January, Bernstein Liebhard LLP Reports 2Health News:Federal Court Overseeing DePuy ASR Hip Lawsuit Set to Convene Conference in January, Bernstein Liebhard LLP Reports 3Health News:iFitDress.com: Black One-Shoulder Cocktail Dresses for 2015 2Health News:The True 9/11 Hero Story “Color of Honor” Premieres in Germany and Bangladesh: Luciana Lagana Plays the Mother of the Lead and Co-Produces with Blaise Dolcemaschio. 2Health News:The True 9/11 Hero Story “Color of Honor” Premieres in Germany and Bangladesh: Luciana Lagana Plays the Mother of the Lead and Co-Produces with Blaise Dolcemaschio. 3Health News:Various Styles of Bamboo Mats in Many Colors from BambooFlooringChina.com 2Health News:Coral Gables Florida Gets Ready to Be Lice-Free with Lice Troopers 2
... MONDAY, Oct. 31 (HealthDay News) -- Certain factors unique to ... contagious norovirus among teams and their staff, a new report ... (often referred to as stomach flu) and causes 21 million ... The report, published in the Oct. 31 online edition of ...
... Just two extra hours of focused training significantly increased ... polyps , known as adenomas, in the colon, according ... These findings suggest that new methods to educate endoscopists, ... colorectal cancer detection rates and potentially reduce cancer ...
... new study describes a 2010 outbreak involving several ... norovirus outbreak in a professional sports association. Published ... online ( http://www.oxfordjournals.org/our_journals/cid/prpaper.pdf ), the study highlights unique ... players and staff on and off the court. ...
... birth control are vastly different from those used by ... hormones and with different means of delivery (not just ... to women,s pleasure remain. An Indiana University ... affect things such as arousal, lubrication and orgasm, found ...
... PHILADELPHIA, PA (October 30 2011)In a technical tour de ... and cross-indexed the actions of 178 candidate drugs capable ... 300 enzymes, including enzymes critical for cancer and other ... been made available online to the research community. This ...
... addicts to repeatedly choose drugs, alcohol, cigarettes, overeating, ... Neuroscientists at the University of California, Berkeley, ... where calculations are made that can result in ... have found how neural activity in the brain,s ...
Cached Medicine News:Health News:Stomach Bug Easily Passed Among Pro Sports Teams: Report 2Health News:Mayo Clinic: Short training course significantly improves detection of precancerous polyps 2Health News:Mayo Clinic: Short training course significantly improves detection of precancerous polyps 3Health News:NBA players not immune to serious illness from norovirus 2Health News:Not your mother's birth control, same troubles 2Health News:First-of-its-kind study creates new tool for targeted cancer drug development 2Health News:First-of-its-kind study creates new tool for targeted cancer drug development 3Health News:UC Berkeley findings offer new clues into the addicted brain 2Health News:UC Berkeley findings offer new clues into the addicted brain 3
(Date:12/24/2014)... , Dec. 24, 2014  Actavis plc ... the Company has received a complete response letter ... for its New Drug Application (NDA) for the ... the treatment of hypertension.   Photo - ... are disappointed in the receipt of a complete ...
(Date:12/24/2014)... Dec. 24, 2014 Soligenix, Inc. (OTCQB: ... company developing products that address unmet medical needs ... announced today that on December 24, 2014 it ... The Company raised approximately $2.3 million in ... use the net proceeds from the offering to ...
(Date:12/24/2014)... FARMINGTON, Conn. , Dec. 24, 2014 /PRNewswire/ ... biopharmaceutical company developing targeted, receptor-specific peptide therapeutics for ... need and commercial potential, today announced that it ... shares of its common stock and Series C ... stock.  Funds under the management of QVT Financial ...
Breaking Medicine Technology:Actavis Confirms Complete Response Letter for Nebivolol/Valsartan Fixed-Dose Combination for Hypertension 2Actavis Confirms Complete Response Letter for Nebivolol/Valsartan Fixed-Dose Combination for Hypertension 3Actavis Confirms Complete Response Letter for Nebivolol/Valsartan Fixed-Dose Combination for Hypertension 4Soligenix Announces Closing of Public Offering of Units 2Soligenix Announces Closing of Public Offering of Units 3Palatin Completes $20 Million Equity and $10 Million Debt Financings 2Palatin Completes $20 Million Equity and $10 Million Debt Financings 3Palatin Completes $20 Million Equity and $10 Million Debt Financings 4
... N.Y., May 2, 2011 Henry Schein, Inc., (NASDAQ: ... and services to office-based practitioners, announced today that ... Schein, and Steven Paladino, the Company,s Executive Vice President and ... Annual Health Care Conference on May 4, 2011. The conference ...
... 2011 Caliper Life Sciences, Inc. (NASDAQ: ... first quarter of 2011.  First quarter revenue increased to ... same period of 2010.  This increase was principally driven ... and license revenues.  Cambridge Research & Instrumentation, Inc. ("CRi"), ...
Cached Medicine Technology:Henry Schein to Present at Deutsche Bank 36th Annual Health Care Conference 2Caliper Life Sciences Reports First Quarter 2011 Results 2Caliper Life Sciences Reports First Quarter 2011 Results 3Caliper Life Sciences Reports First Quarter 2011 Results 4Caliper Life Sciences Reports First Quarter 2011 Results 5Caliper Life Sciences Reports First Quarter 2011 Results 6Caliper Life Sciences Reports First Quarter 2011 Results 7Caliper Life Sciences Reports First Quarter 2011 Results 8Caliper Life Sciences Reports First Quarter 2011 Results 9Caliper Life Sciences Reports First Quarter 2011 Results 10
... The OcuLight family of infrared laser photocoagulators ... models. These diode lasers serve as a ... and applications, require no regular maintenance or ... their compact design. The OcuLight SLx is ...
... Using the latest in solid-state technology, ... green light at 532 nm. Patented ... delivery device options maximize versatility, compact ... and advanced design minimizes any routine ...
... Danker Laboratories manufacturers a ... orthokeratology lenses (also known ... "Corneal Reshaping" Lenses) according ... and demanding standards of ...
... The Euclid Systems Orthokeratology (oprifocon A) ... contact lenses used for orthokeratology, a ... The patient wears these lenses overnight ... During the day, nearsightedness is temporarily ...
Medicine Products: