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Biopure Announces 2007 Fourth Quarter and Year-End Financial Results
Date:1/28/2008

previous surgical studies of Hemopure. They also address the safety and efficacy of both Hemopure and Hemoglobin-based oxygen carriers (HBOCs) in general.

Chief Financial Officer

The company has engaged David A. Butler on a consulting basis as interim CFO. Mr. Butler most recently served as Vice President, Finance and Administration at the Millard Group, Inc., a services and consulting company. Francis H. Murphy, formerly CFO, has retired but continues to serve as a consultant to the company.

Nasdaq

On December 14, 2007 Biopure received notice from the Nasdaq Stock Market that the closing bid price of its common stock had fallen and remained below $1.00 for 30 consecutive business days. Consequently, the company is out of compliance with Nasdaq's $1.00 minimum bid price requirement for continued listing set forth in Marketplace Rule 4310(c)(4). This notification has no effect on the listing of the Common Stock at this time.

Biopure Corporation

Biopure Corporation develops, manufactures and markets pharmaceuticals, called oxygen therapeutics, that are intravenously administered to deliver oxygen to the body's tissues. Hemopure(R) [hemoglobin glutamer - 250 (bovine)], or HBOC-201, is approved for sale in South Africa for the treatment of surgical patients who are acutely anemic. Biopure has applied in the United Kingdom for regulatory approval of a proposed orthopedic surgical anemia indication. The company is developing Hemopure for other indications and is supporting the U.S. Navy's government-funded efforts to develop a potential out-of-hospital trauma indication. Biopure's veterinary product Oxyglobin(R) [hemoglobin glutamer - 200 bovine)], or HBOC-301, the only oxygen therapeutic approved for marketing by both the U.S. Food and Drug Administration and the European Commission, is indicated for the treatment of anemia in dogs. Biopure has sold approximately 190,000 units of Oxyglobin.

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