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Bionovo to Present Recent Findings of BN108, its Anticancer Agent, at the 31st Annual San Antonio Breast Cancer Symposium
Date:12/12/2008

EMERYVILLE, Calif., Dec. 12 /PRNewswire-FirstCall/ -- Bionovo, Inc. (Nasdaq: BNVI) will present findings on the mechanism of action of its anti-cancer agent BN108 at the 31st Annual San Antonio Breast Cancer Symposium being held at the Henry B. Gonzalez Convention Center, San Antonio TX, December 10-14, 2008.

Bionovo's poster presentation will describe the pathway for cancer cell apoptosis (cell death) induced by BN108. As explained by Dr. Emma Shtivelman, Director of Cancer Research at Bionovo, BN108 induces death in cancer cells but not in normal cells. BN108 induces apoptosis through induction of stress in the endoplasmic reticulum. Laboratory studies show that BN108 inhibits major oncogenic pathways, and therefore, can be used for many different cancers.

"BN108 mechanism of action and unique selective properties are a result of some of the distinct biological differences between cancer cells and normal cells. We believe BN108 will result in better selectivity to various cancers with no collateral damage to normal tissues. BN108 is designed to be an oral drug candidate that will provide a chronic treatment option with a low toxicity profile," said Dr. Isaac Cohen, Chairman and CEO of Bionovo,

Bionovo, Inc.

Bionovo is a pharmaceutical company focused on the discovery and development of safe and effective treatments for women's health and cancer, markets with significant unmet needs and billions in potential annual revenue. The company applies its expertise in the biology of menopause and cancer to design new drugs derived from botanical sources which have novel mechanisms of action. Based on the results of early and mid-stage clinical trials, Bionovo believes they have discovered new classes of drug candidates within their rich pipeline with the potential to be leaders in their markets. Bio
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SOURCE Bionovo, Inc.
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