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Bioniche Presents Pre-Clinical Research at Two International Conferences
Date:5/23/2008

rs in Modern Vaccines Conference

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Bioniche Life Sciences Inc. was invited to present at the Immunopotentiators in Modern Vaccines Conference in Montego Bay, Jamaica, this week. The presentation, entitled, "Mycobacteria-derived immunopotentiating molecules and their application in vaccine development", was made by Dr. Nigel C. Phillips, Chief Scientific Officer of Bioniche Life Sciences Inc.

Dr. Phillips discussed the development pathway from MCC to the Company's synthetic oligonucleotides, and reviewed their immune stimulatory and immune adjuvant activity. "The data presented clearly demonstrate that the Company's proprietary, synthetic, non-CpG containing oligonucleotides have immune stimulant activity (cytokine induction and activation of antigen presenting cells)," said Dr. Phillips. "This is in addition to the previously reported direct anticancer activity. They appear to have considerable potential as vaccine adjuvants, as demonstrated in proof-of-principle animal studies using human hepatitis B surface antigen. Mechanistic studies indicate that they have a unique mode of action in their ability to stimulate immune responses."

About the Oligonucleotide Technology Platform

In 2000, Bioniche announced the discovery of a new class of molecules with potential anticancer activity, referred to by the Company under the trademark, "Oligomodulator(TM)". This new class of molecules with potential clinical anticancer activity and immune modulating properties is composed of short non-antisense DNA oligonucleotides that appear to possess a range of novel pharmacological activities.

About MCC

MCC is a sterile mycobacterial cell wall-DNA complex composition that has a dual mode of action: immune stimulation and direct anticancer activity. It is formulated as Urocidin(TM) for the treatment of bladder cancer, where it is administered by trans-urethral catheter direct
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SOURCE Bioniche Life Sciences Inc.
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