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Bioniche Presents E. coli O157:H7 Vaccine Data to International Congress of Medical Microbiology in Serbia
Date:6/17/2008

BELLEVILLE, ON, June 17 /PRNewswire-FirstCall/ - Bioniche Life Sciences Inc. (TSX: BNC), a research-based, technology-driven Canadian biopharmaceutical company, presented data regarding its E. coli O157:H7 cattle vaccine at the 6th Congress of Medical Microbiology - Mikromed 2008 in Belgrade, Serbia last weekend. The presentation was made by Dr. Dragan Rogan, Vice-President, Bioniche Animal Health Research & Development.

The Bioniche vaccine is the world's first vaccine that may be used as an on-farm intervention to reduce the amount of E. coli O157:H7 shed by cattle. Bioniche and its collaborators have been moving the vaccine towards commercial availability for eight years and it has been extensively tested at the University Nebraska-Lincoln, with efficacy results now being published in peer-reviewed scientific journals, most recently, the Journal of Food Protection, in November, 2007.

In his presentation, Dr. Rogan summarized numerous studies that have been completed with the Bioniche vaccine over the last five years involving more than 30,000 cattle. It has been identified that approximately 60% of cattle have more than 20% prevalence of E. coli O157:H7 in the summer months, while only 10% have this level of prevalence in winter. The results of studies conducted with the Bioniche E. coli O157:H7 vaccine indicate that winter shedding levels can be approximated by vaccinating summer-fed cattle. "This establishes proof-of-concept for vaccination as a useful pre-harvest intervention against E. coli O157:H7," said Dr. Rogan. "Vaccination of an entire feedlot will have a dramatic effect on E. coli cycling in the feedlot and, over time, has the potential to decrease the environmental load and subsequent re-infection with each successive cycle."

Food recalls due to E. coli O157:H7 contamination continue to be a concern in beef, produce and prepared food. On-farm interventions to reduce the shedding of E. coli O157:H7 by cattle, such as vaccina
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SOURCE Bioniche Life Sciences Inc.
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3. Bioniche Food Safety Vaccine Receives Global Top Honours in Industry Excellence Awards
4. Bioniche Receives Comment from USDA on a Field Trial for E. coli O157:H7 Cattle Vaccine
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