Navigation Links
Biomarkers in blood show potential as early detection method of pancreatic cancer
Date:1/21/2014

Researchers have identified diagnostic microRNA panels in whole blood that had the ability to distinguish, to some degree, patients with and without pancreatic cancer, according to a study in the January 22/29 issue of JAMA. The authors caution that the findings are preliminary, and that further research is necessary to understand whether these microRNAs have clinical implications as a screening test for early detection of pancreatic cancer.

MicroRNAs regulate gene expression and play important roles in the development of tumors and tumor metastasis. MicroRNA panels are a combination of several microRNAs.

Pancreatic cancer is the fourth most common cause of cancer death in the Western world and prognosis is poor, according to background information in the article. Early diagnosis of pancreatic cancer is difficult partly because it is difficult to get useful biopsies of tissue from patients suspected of having pancreatic cancer, so markers of the disease that could help with early diagnosis are needed to improve prognosis. Several specific microRNA profiles (patterns of microRNAs) have been linked to pancreatic cancer tissue. A diagnostic noninvasive blood test for pancreatic cancer would be very valuable, the authors write.

Nicolai A. Schultz, M.D., Ph.D., of Herlev Hospital, Copenhagen University Hospital, Copenhagen, Denmark, and colleagues examined differences in microRNA in whole blood between patients with pancreatic cancer (n = 409) and healthy participants (n = 312) and patients with chronic pancreatitis (n = 25) to identify diagnostic panels of microRNAs for use in the diagnosis of pancreatic cancer. Serum cancer antigen 19-9 (CA19-9; an antigen that is elevated in approximately 80 percent of patients with pancreatic cancer) was also measured for comparison.

The researchers identified 2 novel panels with the potential for diagnosing pancreatic cancer.

The authors write that the test could result in
'/>"/>

Contact: Julia S. Johansen
julia.johansen@post3.tele.dk
The JAMA Network Journals
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Molecular Biomarkers for Cancer Detection and Management
2. MUHC researchers identify biomarkers that could leadto early diagnosis of colorectal cancer
3. Mount Sinai Researchers Identify Mechanisms and Potential Biomarkers of Tumor Cell Dormancy
4. Global Biomarkers Market - Industry Analysis, Size, Share, Growth, Trends and Forecast, 2013 - 2019
5. Macrophage-derived mediators may have potential as biomarkers for urinary stone risk
6. Biomarkers Market Worth $25.79 Billion by 2016 – New Report by MarketsandMarkets
7. Researchers to identify genetic biomarkers for aggressive breast cancer
8. Researchers develop specific tests to identify cancer biomarkers in dermatomyositis
9. Global Oncology Biomarkers Market to Reach US $9.5 Billion by 2014 at a CAGR of 18.1% - New Report by MarketsandMarkets
10. New concussion data: 2 biomarkers better than 1
11. Researchers narrow the search for biomarkers of drug resistance in head and neck cancer patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/6/2015)... As the exclusive hospital of the Tampa Bay Buccaneers, Florida ... Raymond James Stadium for all the “Bucs Babies” celebrating their ... into the “Bucs Babies” program last year. , “It ... particularly those born at the Florida Hospitals here in our ... really enjoyed my time participating in the festivities, interacting with ...
(Date:5/6/2015)... 2015 On April 27, 2015, Elle ... Surgery ,” compiled quotes about cosmetic surgery from 16 ... singer Iggy Azalea, and Gwyneth Paltrow. For the most ... plastic surgery themselves; only a couple of ... expectations of youth and beauty. (see: goo.gl/wSomih) , “The ...
(Date:5/6/2015)... May 06, 2015 Chesapeake Regional ... state of Virginia to acquire Intuitive Surgical, Inc.’s ... The system upgrade includes enhanced surgical technique capabilities, ... procedures across a wide spectrum of specialties. Its ... pain and quicker recovery times. , “As the ...
(Date:5/6/2015)... PA (PRWEB) May 06, 2015 TMG ... solutions to the Medicare Advantage, Medicare Part D and ... the Continuity and Resilience Team category at the BCI ... Continuity Institute to recognize the outstanding contribution of business ... the North America Region, including the USA and Canada. ...
(Date:5/6/2015)... Boulder, CO (PRWEB) May 06, 2015 ... Boulder, Colo., specializes in yoga and Pilates classes, ... services, videos and products, starting with its new ... In the effort of becoming leaner, stronger, more ... Pilates Ring offer a fresh venue to healthy ...
Breaking Medicine News(10 mins):Health News:Florida Hospital and the Tampa Bay Buccaneers Celebrate “Bucs Babies” Who are Turning One this Month with a Party on the Pirate Ship 2Health News:Florida Hospital and the Tampa Bay Buccaneers Celebrate “Bucs Babies” Who are Turning One this Month with a Party on the Pirate Ship 3Health News:Plastic Surgery: Sixteen Celebrities Offer their Opinion about Going Under the Knife 2Health News:Chesapeake Regional Medical Center Obtains First da Vinci® XI Robotic Surgical System in Virginia 2Health News:Chesapeake Regional Medical Center Obtains First da Vinci® XI Robotic Surgical System in Virginia 3Health News:TMG Health Recognized by the Business Continuity Institute 2Health News:TMG Health Recognized by the Business Continuity Institute 3Health News:Inversion Studios’ New Pilates Ring Is Circle of Magic for Body, Mind and Spirit 2Health News:Inversion Studios’ New Pilates Ring Is Circle of Magic for Body, Mind and Spirit 3
... twice before buying their next pair of high-heels or pumps, ... Hebrew SeniorLife in a new study of older adults and ... women wear, specifically high-heels, pumps and sandals, may cause future ... who reported hind-foot pain regularly wore these types of shoes ...
... individuals from the field of pharmaceutical research are expected to ... - 12, 2009 at the Los Angeles Convention Center in ... have the opportunity to present new research, methods and technologies ... only is the meeting the premiere international event for the ...
... ... healthcare professionals, today announced that it has acquired the assets of Medical Concepts Staffing ... , ... (PRWEB) September 28, 2009 -- Temps Inc., ( www.tempsinc.net ) a national provider of ...
... cons of cancer screen not understood, research shows, , MONDAY, ... told the pros and cons of PSA tests, two new ... they can,t predict which cancers are aggressive and which are ... leads to overtreatment, which can have immediate consequences, such as ...
... cells to ignore premature signals to stop producing important proteins. ... Journal of Experimental Medicine , the findings could lead to ... dystrophy, that are sparked by missing proteins. "When DNA ... than the end of a protein-producing signal, they act like ...
... of Common Human Disease has been chosen as one ... of Health (NIH) grant for Centers of Excellence to ... million over five years. "We,re grateful for ... how epigenetic control affects disease," says the center,s director, ...
Cached Medicine News:Health News:Institute for Aging Research study links high-heels to heel and ankle pain 2Health News:Temps Inc. Acquires Medical Concepts Staffing Business From Analysts International Corporation 2Health News:Men Not Being Told Enough About PSA Tests 2Health News:Men Not Being Told Enough About PSA Tests 3Health News:Men Not Being Told Enough About PSA Tests 4Health News:UCLA study identifies 2 chemicals that could lead to new drugs for genetic disorders 2
(Date:5/6/2015)... Johnson & Johnson (NYSE: JNJ ) ... party to review requests made to the Janssen Pharmaceutical ... compassionate use of its investigational medicines. This new approach ... single Janssen investigational medicine and, if successful, will become ... Johnson & Johnson. In keeping with the ...
(Date:5/6/2015)... 6, 2015  Zimmer Holdings, Inc. (NYSE and SIX: ZMH), ... will be presenting at the Bank of America Merrill Lynch ... Las Vegas, Nevada on Wednesday, May ... live webcast of the presentation can be accessed via Zimmer,s ... be archived for replay following the conference. About ...
(Date:5/6/2015)... NEW YORK , May 6, 2015  The ... ("GEVA" or the "Company") by Alexion Pharmaceuticals, Inc. ("Alexion") ... action, shareholder rights law firm, for possible breaches of ... Board of Directors of GEVA for agreeing to sell ... Company announced a definitive agreement for Alexion to acquire ...
Breaking Medicine Technology:Johnson & Johnson Announces NYU School of Medicine Partnership To Evaluate Compassionate Use of Investigational Medicines 2Johnson & Johnson Announces NYU School of Medicine Partnership To Evaluate Compassionate Use of Investigational Medicines 3Johnson & Johnson Announces NYU School of Medicine Partnership To Evaluate Compassionate Use of Investigational Medicines 4Johnson & Johnson Announces NYU School of Medicine Partnership To Evaluate Compassionate Use of Investigational Medicines 5WeissLaw LLP Investigates the Synageva Biopharma Corp. Acquisition 2
... Neuralstem, Inc. (NYSE Amex: CUR ) announced ... trial to test its neuroregenerative small molecule drug, NSI-189, in ... the drug in healthy volunteers for safety and tolerability. Phase ... will test the safety and tolerability of NSI-189 in depressed ...
... Since its initial inception, Echosens has ... and strengthen its product range with the recent introduction ... Equipped with a new and more ergonomic tactile interface, ... latest FibroScan ® provides a reliable, accurate and ...
Cached Medicine Technology:Neuralstem Completes Phase Ia in Neuroregenerative Small Molecule Drug, NSI-189, Major Depressive Disorder Trial 2Neuralstem Completes Phase Ia in Neuroregenerative Small Molecule Drug, NSI-189, Major Depressive Disorder Trial 3Echosens: Launch of the FibroScan®502 Touch 2
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: