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Biomarkers detected for Chikungunya fever
Date:3/4/2009

e development of future therapeutic applications.

This research is being conducted through a follow-up on more than 100 cases of CHIKF, to further refine the understanding of CHIKF clinical manifestation over a prolonged period of time.

Prof. Leo added, "We are hopeful that our research endeavor can further our understanding of Chikungunya and enable us to apply the knowledge gained to better manage the disease".

With outbreaks in the Pacific region in recent years, CHIKF has emerged as a potentially serious international health threat. However, little is known about the disease progression and the immune response in patients. In late 2007, SIgN initiated clinical immunology research on Chikungunya led by Dr. Lisa Ng to study the immunological process of CHIKF.

During the 2008 outbreak of CHIKF in Singapore, the CDC team led by Associate Professor Leo Yee Sin, Clinical Director of the CDC, TTSH, responded swiftly to contain it and set up outbreak research through the support of National Healthcare Group Domain-Specific Review Boards. CDC's swift action enabled prospective sample collection at a very early stage of the outbreak, which allowed the research team to study early cytokine response.


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Contact: Cathy Yarbrough
sciencematter@yahoo.com
858-243-1814
Agency for Science, Technology and Research (A*STAR), Singapore
Source:Eurekalert

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