Navigation Links
Biomarkers can reveal IBS
Date:5/7/2012

Irritable bowel syndrome (IBS) is hard to diagnose as well as treat, but researchers at the Sahlgrenska Academy, at the University of Gothenburg, Sweden, have discovered a way of confirming the disorder using stool samples.

Irritable bowel syndrome (IBS) causes chronic or recurring problems with pain and discomfort in the abdomen together with changes in bowel habits. The syndrome is common and is believed to be linked to dysfunction of the stomach and intestines, but our understanding of IBS is incomplete, making it difficult to diagnose and treat.

Identified specific proteins

Researchers at the Sahlgrenska Academy have now identified specific proteins that can be used to identify patients with IBS: "The proteins we've been investigating, granins, are found in various forms with different functions in the nervous, immune and digestive systems," explains researcher Lena hman. "Our studies show that IBS patients have higher levels of some granins and lower levels of others in their faeces."

Hope for new treatments

Further studies are needed, but if granins can be used to diagnose IBS, it is hoped that this will contribute to the development of new treatments. The study, which compared 82 IBS patients with 29 healthy subjects, was published in the American Journal of Gastroenterology.

About the study:

Granins (chromogranin A) have previously been shown to serve as biomarkers for other inflammatory diseases in the gut, such as ulcerous colitis and Crohn's disease. The present study looked at the variants secretogranin II and chromogranin B and found that IBS patients have high levels of the former and low levels of the latter.


'/>"/>
Contact: Lena hman
lena.ohman@microbio.gu.se
46-031-786-6214
University of Gothenburg
Source:Eurekalert  

Page: 1

Related medicine news :

1. Researchers find biomarkers in saliva for detection of early-stage pancreatic cancer
2. Personalizing cancer: Creating biomarkers from tumor DNA
3. Reliable biomarkers needed for early detection of liver cancer
4. More Reliable Biomarkers Needed for Early Detection of Liver Cancer
5. UAB researchers find 4 biomarkers important in colerectal cancer treatment prognosis
6. BATTLE links potential biomarkers to drugs for lung cancer
7. UAB researchers find 4 biomarkers important in colorectal cancer treatment prognosis
8. Hydrophobic proteins: Potential biomarkers for colorectal cancer
9. Biomarkers Could Spot Alzheimers Disease Early, Studies Suggest
10. Biomarkers May Aid in Early Diagnosis of Alzheimers
11. Mayo researchers find biomarkers for personalizing radiation cancer treatment
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Biomarkers can reveal IBS
(Date:7/21/2017)... ... July 21, 2017 , ... The Margarian Law Firm has ... contents of its ginger ale for allegedly containing no ginger. Dr. Pepper produces the ... Group, Inc., plaintiff Gegham Margaryan alleges Canada Dry Ginger Ale claims on its bottle ...
(Date:7/21/2017)... ... July 21, 2017 , ... ... students improve their chances of acceptance to a residency in a United States ... earned degrees outside the U.S. , According to data released by the ECFMG®, ...
(Date:7/21/2017)... ... 21, 2017 , ... West Dermatology is pleased to announce the newest addition ... 2017, Ms. Vu will join West Dermatology’s large network of medical and cosmetic dermatology ... cancer , and more. She graduated from the University of Florida College of Medicine ...
(Date:7/21/2017)... , ... July 21, 2017 , ... ... why concussion rates are on the rise, say researchers presenting their work at ... Toronto, Ontario, Canada. , “The combination of evaluating the patterns of change in ...
(Date:7/20/2017)... ... July 20, 2017 , ... ... bone marrow cancer that progresses rapidly without treatment. Newly diagnosed patients face intense ... chance of reoccurrence and relapse. With such a challenging diagnosis that requires ...
Breaking Medicine News(10 mins):
(Date:7/5/2017)... MINNEAPOLIS , July 5, 2017 Pace Analytical, a company of ... announcing today that they have acquired ESC Lab Sciences, further solidifying their position ... the United States . ... Steve Vanderboom- President and CEO of Pace Analytical ... of ESC Lab Sciences out of Mt Juliet, TN , ...
(Date:7/1/2017)... -- Zimmer Biomet Holdings, Inc. (NYSE and SIX: ZBH) today ... be broadcast live over the Internet on Thursday, July 27, ... the quarterly results will be made available at 7:30 a.m. ... The live audio webcast can be accessed via Zimmer Biomet,s ... archived for replay following the conference call. ...
(Date:6/30/2017)... Medical (AVACEN) announced the publication of new research in the peer-reviewed ... AVACEN Treatment Method to significantly reduce the widespread pain ... ... ... 200 to 400 million people worldwide according to The National Fibromyalgia ...
Breaking Medicine Technology: