Navigation Links
Biomarkers can reveal IBS
Date:5/7/2012

Irritable bowel syndrome (IBS) is hard to diagnose as well as treat, but researchers at the Sahlgrenska Academy, at the University of Gothenburg, Sweden, have discovered a way of confirming the disorder using stool samples.

Irritable bowel syndrome (IBS) causes chronic or recurring problems with pain and discomfort in the abdomen together with changes in bowel habits. The syndrome is common and is believed to be linked to dysfunction of the stomach and intestines, but our understanding of IBS is incomplete, making it difficult to diagnose and treat.

Identified specific proteins

Researchers at the Sahlgrenska Academy have now identified specific proteins that can be used to identify patients with IBS: "The proteins we've been investigating, granins, are found in various forms with different functions in the nervous, immune and digestive systems," explains researcher Lena hman. "Our studies show that IBS patients have higher levels of some granins and lower levels of others in their faeces."

Hope for new treatments

Further studies are needed, but if granins can be used to diagnose IBS, it is hoped that this will contribute to the development of new treatments. The study, which compared 82 IBS patients with 29 healthy subjects, was published in the American Journal of Gastroenterology.

About the study:

Granins (chromogranin A) have previously been shown to serve as biomarkers for other inflammatory diseases in the gut, such as ulcerous colitis and Crohn's disease. The present study looked at the variants secretogranin II and chromogranin B and found that IBS patients have high levels of the former and low levels of the latter.


'/>"/>
Contact: Lena hman
lena.ohman@microbio.gu.se
46-031-786-6214
University of Gothenburg
Source:Eurekalert  

Page: 1

Related medicine news :

1. Researchers find biomarkers in saliva for detection of early-stage pancreatic cancer
2. Personalizing cancer: Creating biomarkers from tumor DNA
3. Reliable biomarkers needed for early detection of liver cancer
4. More Reliable Biomarkers Needed for Early Detection of Liver Cancer
5. UAB researchers find 4 biomarkers important in colerectal cancer treatment prognosis
6. BATTLE links potential biomarkers to drugs for lung cancer
7. UAB researchers find 4 biomarkers important in colorectal cancer treatment prognosis
8. Hydrophobic proteins: Potential biomarkers for colorectal cancer
9. Biomarkers Could Spot Alzheimers Disease Early, Studies Suggest
10. Biomarkers May Aid in Early Diagnosis of Alzheimers
11. Mayo researchers find biomarkers for personalizing radiation cancer treatment
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Biomarkers can reveal IBS
(Date:6/24/2016)... ... ... National recruitment firm Slone Partners is pleased to announce the ... as Vice President of North American Capital Sales at HTG Molecular . ... team in the commercialization of the HTG EdgeSeq system and associated reagents in North ...
(Date:6/24/2016)... ... June 24, 2016 , ... Today, MTI-GlobalStem, a ... cells and other difficult to transfect cells, announces its launch of the PluriQ™ ... Gene Editing System is a complete system for culturing and transfecting human ...
(Date:6/24/2016)... ... June 24, 2016 , ... Finally, a bruise cream that really works. ... be incorporated into the post-surgical treatment plans of a variety of other procedures including, ... is very effective for bruising and causes a rapid resolution of bruising and inflammatory ...
(Date:6/24/2016)... ... 2016 , ... Southern Illinois University School of Dental Medicine ... State Dental Society (ISDS) Foundation’s Mission of Mercy (MOM). They will host a ... , They expect to treat approximately 2,000 patients from Illinois, Missouri, ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... SpiritQuest Sedona ... heart of West Sedona, surrounded by famous vortex sites: Cathedral Rock, Airport Mesa, and ... partner properties – the Lodge at Sedona as well as the Sedona Rouge, both ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 2016 Research and Markets ... Electronics 2015-2025: Applications, Technologies, Forecasts" report to ... In-Mold Electronics, Smart Skin, Structural Health Monitoring, Composite ... Structural electronics involves electronic and/or electrical components and ... dumb structures such as vehicle bodies or conformally ...
(Date:6/24/2016)... SAN CLEMENTE, Calif. , June 24, 2016 /PRNewswire/ ... pulmonary function testing company, is now able to perform sophisticated lung ... ndd Medical Technologies , Inc. Patients are ... labs.  Thanks to ndd,s EasyOne PRO ® , ARL patients like ... any needed testing done in the comfort of her own home. ...
(Date:6/24/2016)... Mass. , June 24, 2016   Pulmatrix, ... pharmaceutical company developing innovative inhaled drugs, announced today that ... Russell Investments reconstituted its comprehensive set of ... "This is an important milestone for Pulmatrix," ... will increase shareholder awareness of our progress in developing ...
Breaking Medicine Technology: