Navigation Links
Biomarkers can reveal IBS
Date:5/7/2012

Irritable bowel syndrome (IBS) is hard to diagnose as well as treat, but researchers at the Sahlgrenska Academy, at the University of Gothenburg, Sweden, have discovered a way of confirming the disorder using stool samples.

Irritable bowel syndrome (IBS) causes chronic or recurring problems with pain and discomfort in the abdomen together with changes in bowel habits. The syndrome is common and is believed to be linked to dysfunction of the stomach and intestines, but our understanding of IBS is incomplete, making it difficult to diagnose and treat.

Identified specific proteins

Researchers at the Sahlgrenska Academy have now identified specific proteins that can be used to identify patients with IBS: "The proteins we've been investigating, granins, are found in various forms with different functions in the nervous, immune and digestive systems," explains researcher Lena hman. "Our studies show that IBS patients have higher levels of some granins and lower levels of others in their faeces."

Hope for new treatments

Further studies are needed, but if granins can be used to diagnose IBS, it is hoped that this will contribute to the development of new treatments. The study, which compared 82 IBS patients with 29 healthy subjects, was published in the American Journal of Gastroenterology.

About the study:

Granins (chromogranin A) have previously been shown to serve as biomarkers for other inflammatory diseases in the gut, such as ulcerous colitis and Crohn's disease. The present study looked at the variants secretogranin II and chromogranin B and found that IBS patients have high levels of the former and low levels of the latter.


'/>"/>
Contact: Lena hman
lena.ohman@microbio.gu.se
46-031-786-6214
University of Gothenburg
Source:Eurekalert  

Page: 1

Related medicine news :

1. Researchers find biomarkers in saliva for detection of early-stage pancreatic cancer
2. Personalizing cancer: Creating biomarkers from tumor DNA
3. Reliable biomarkers needed for early detection of liver cancer
4. More Reliable Biomarkers Needed for Early Detection of Liver Cancer
5. UAB researchers find 4 biomarkers important in colerectal cancer treatment prognosis
6. BATTLE links potential biomarkers to drugs for lung cancer
7. UAB researchers find 4 biomarkers important in colorectal cancer treatment prognosis
8. Hydrophobic proteins: Potential biomarkers for colorectal cancer
9. Biomarkers Could Spot Alzheimers Disease Early, Studies Suggest
10. Biomarkers May Aid in Early Diagnosis of Alzheimers
11. Mayo researchers find biomarkers for personalizing radiation cancer treatment
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Biomarkers can reveal IBS
(Date:2/18/2017)... Dallas, Texas (PRWEB) , ... February 17, 2017 , ... ... Arden Moore’s “Oh Behave” Show on the Pet Life Radio network. The episode, ... explores a number of topics including: what factors led to Park Cities Pet Sitter’s ...
(Date:2/17/2017)... CA (PRWEB) , ... February 17, 2017 , ... ... focus on foundational and sustainable systems change designed to further positively impact the ... “The Board of Trustees has long considered it our duty to seriously consider ...
(Date:2/17/2017)... ... February 17, 2017 , ... Corrective ... Warning Letter, **An FDAnews Webinar**, Feb. 23, 2017 — 1:30 p.m. – 3:00 ... corrective action (CA) and preventive action (PA)? , The methods share techniques and ...
(Date:2/17/2017)... ... February 17, 2017 , ... Pharmica Consulting attended CHI's ... facets of clinical trial planning and management. Pharmica discussed the importance of effective ... addition, attendees stopping by Pharmica’s booth were able to demo its cloud-based ...
(Date:2/17/2017)... ... 2017 , ... The Mason Pasquin Agency, a Virginia-based firm ... in and around the Hampton Roads metropolitan region, is joining the local nonprofit ... violence. , There are multiple categories of domestic violence – physical abuse is ...
Breaking Medicine News(10 mins):
(Date:2/16/2017)... DaVita Inc. (NYSE: DVA ) today ... 2016. Net income attributable to DaVita Inc. ... $158 million, or $0.80 per share and $880 million, or ... attributable to DaVita Inc. for the quarter and year ended ... $192 million, or $0.98 per share, and $789 million, or ...
(Date:2/16/2017)... -- Newly published research from the CVS Health (NYSE: ... private retailer can play in restricting access to tobacco ... in the American Journal of Public Health , ... all CVS Pharmacy stores reduced the number of cigarette ... impact on those who bought cigarettes exclusively at CVS ...
(Date:2/16/2017)... 16, 2017  Prescription pain medications provided by "physicians ... necessary for long-term opioid use to take hold," according ... edition of The New England Journal of ... more patients in acute pain than in almost any ... FACEP, president of the American College of Emergency Physicians. ...
Breaking Medicine Technology: