Navigation Links
'Biomarkers' Could Spot Alzheimer's Disease Early, Studies Suggest
Date:8/9/2010

t of those with mild cognitive impairment (MCI) and 36 percent of those who had no cognitive impairments.

A signature consisting of low amyloid levels and high phosphorylated tau levels identified patients with MCI who progressed to Alzheimer's with 100 percent accuracy, the team said.

The fact that the signature was also found in individuals with no sign of cognitive impairment underlines the likelihood that Alzheimer's disease has started long before it is symptomatic, stated the authors.

Another research group, this one set to report its finding in the December print issue of the Archives of Neurology verified that blood levels of the beta-amyloid protein predict progression toward Alzheimer's -- another step towards identifying valid biomarkers for the disease.

Patients who started out with high levels of the protein that later tapered off, saw their cognitive health decline more rapidly, even if they did not end up with full-blown Alzheimer's.

"High baseline levels of amyloid beta in combination with declining levels over time was sort of a high-risk profile for the development of Alzheimer's disease," explained study first author Stephanie Cosentino, an assistant professor of neuropsychology at Columbia University's Taub Institute in New York City.

The findings support the "amyloid cascade" theory of Alzheimer's, "which points to the accumulate of amyloid in brain as primary trigger for Alzheimer's disease," Cosentino said.

"This paper, which replicated an [earlier] study on these three risk genes indicates that ultimately, genetic biomarkers may play a very strong role in the whole spectrum of biomarkers [involved in Alzheimer's]," stated Carrillo, who was not involved with either study.

But, Cosentino cautioned, "amyloid beta is not ready to be used as a disease biomarker. Not everyone who has high levels of plasma amyloid beta will demonstrate Alzheimer's disease or cognitive decline. Other factors ne
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. Hydrophobic proteins: Potential biomarkers for colorectal cancer
2. UAB researchers find 4 biomarkers important in colorectal cancer treatment prognosis
3. BATTLE links potential biomarkers to drugs for lung cancer
4. UAB researchers find 4 biomarkers important in colerectal cancer treatment prognosis
5. More Reliable Biomarkers Needed for Early Detection of Liver Cancer
6. Reliable biomarkers needed for early detection of liver cancer
7. Personalizing cancer: Creating biomarkers from tumor DNA
8. Researchers find biomarkers in saliva for detection of early-stage pancreatic cancer
9. Your Pets Food Dish Could Serve Up Salmonella
10. Study finds proximity could be key to success of healing prayer
11. New imaging technique could help physicians ease the aftermath of breast cancer
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
'Biomarkers' Could Spot Alzheimer's Disease Early, Studies Suggest
(Date:9/30/2014)... September 30, 2014 Catalent Pharma ... advanced delivery technologies and development solutions for drugs, ... full agenda for the 25th Annual CPhI Worldwide ... October 6th to 9th. , Catalent is showcasing ... expansions during the show, including its facilities in ...
(Date:9/30/2014)... Coast Dental and Orthodontics is ... practice, located at 1010 Shaw Avenue in Clovis, CA. ... services , and specialty dental care including orthodontics, endodontics, ... and convenient dental care, our Clovis dentists also strive ... Coast Dental at 559-777-6113 to schedule an appointment. , ...
(Date:9/30/2014)... September 30, 2014 With accolades like the ... Lash Masters II, Hilaree Brand of My Brand Lashes is ... craft and, more importantly, the ability to teach. She leads ... credentials and a great reputation. , With a background in ... a Master of Aesthetics and as an Instructor. She has ...
(Date:9/30/2014)... NY, September 30, 2014Levothyroxine (L-T4), long the standard ... most patients, but some individuals do not regain ... thyroid physiology may help to explain these differences. ... Association on thyroid hormone replacement reviewed the latest ... to determine whether a change to the current ...
(Date:9/30/2014)... Pittsburgh School of Dental Medicine have been awarded a ... Dental and Craniofacial Research, part of the National Institutes ... roots of cleft lip and cleft palate and to ... the Philippines and Pennsylvania. , Orofacial clefts (OFCs), ... that can form when a baby,s mouth doesn,t develop ...
Breaking Medicine News(10 mins):Health News:Catalent Showcases Advanced Technologies and Supply Capabilities at CPhI Worldwide Conference and Exhibition 2Health News:Catalent Showcases Advanced Technologies and Supply Capabilities at CPhI Worldwide Conference and Exhibition 3Health News:Coast Dental Clovis Celebrates Grand Opening 2Health News:Coast Dental Clovis Celebrates Grand Opening 3Health News:My Brand Lashes and Lash Affair By J. Paris Merge to Offer Premium Lash and Brow Products and Certifications 2Health News:My Brand Lashes and Lash Affair By J. Paris Merge to Offer Premium Lash and Brow Products and Certifications 3Health News:New hypothyroidism treatment guidelines from American Thyroid Association 2Health News:Pitt team searches for genetic roots of cleft lip, palate 2
... latest advancement in aspirin delivery ... ... has,rolled out Fasprin(R), a patented, 81 milligram aspirin tablet that,dissolves rapidly ... solution for the millions of Americans who maintain a,daily aspirin routine ...
... Formulas No Better than Generic Store-Brand Infant,Formulas, Says Mayo Clinic ... ... GORDONSVILLE, Va., Nov. 13 The Mayo Clinic, a ... every type of complex illness, now offers an online resource ...
... Awareness and Funds to Fight Homelessness in Los ... LOS ANGELES, Nov. 13 United Way of Greater ... to fight homelessness on,Saturday morning, November 17, 2007, by ... Exposition Park near downtown Los Angeles.,HomeWalk will engage participants ...
... Groundbreaking Meeting Brings Together Cancer Funding Organizations, Advocates, Government ... ... Pharmaceutical Industry, NEW YORK, Nov. 13 Leadership ... and advocacy groups met,on November 1-2 along with experts ...
... of America (GSA) has chosen W. Andrew Achenbaum of ... the Donald P. Kent Award. This distinguished honor is ... the highest standards for professional leadership in gerontology through ... society. , The award presentation will take place ...
... chosen Nancy L. Pedersen of Sweden,s Karolinska Institutet to ... to Gerontology. This prize is given annually to an ... new synthesis and perspective or have yielded original and ... literature. , The award presentation will take place at ...
Cached Medicine News:Health News:New, No-Swallow Fasprin(R) Reduces Problems Associated with Daily Aspirin Regimen 2Health News:Mayo Clinic Supports Store-Brand Infant Formulas 2Health News:United Way of Greater Los Angeles and Fannie Mae Foundation Announce 3000 Marchers for HomeWalk 2007 2Health News:United Way of Greater Los Angeles and Fannie Mae Foundation Announce 3000 Marchers for HomeWalk 2007 3Health News:First-Ever Collaborative Summit on Breast Cancer Research Targets New Partnerships and Collaborative Solutions 2Health News:First-Ever Collaborative Summit on Breast Cancer Research Targets New Partnerships and Collaborative Solutions 3Health News:First-Ever Collaborative Summit on Breast Cancer Research Targets New Partnerships and Collaborative Solutions 4
(Date:9/30/2014)... , Sept. 30, 2014 A study using ... offered a new look at the composition of carotid ... physicians understand and treat the disease, a leading cause ... Baptist Health Lexington between September 2010 and May 2012, ... Journal of the American College of Cardiology (JACC) ...
(Date:9/30/2014)... 30, 2014  HealthLoop® released an app version of ... iOS 8 and allows people to share medical device ... native iOS technologies to enhance the HealthLoop experience for ... with their doctors between visits. "This ... they collect is exciting," says HealthLoop founder Dr. ...
(Date:9/30/2014)...  Georgia-Pacific Professional is a leading provider of ... wide range of away from home applications. Building ... healthcare, including hospitals, long-term care facilities, surgical centers ... healthcare products and solutions to the dental community. ... infection control in the dental office," said ...
Breaking Medicine Technology:New Imaging Tool May Allow Tailoring of Stroke Prevention to Each Patient 2HealthLoop Integrates with Apple's HealthKit Enabling Patients to Share Health Data with Their Doctors Right from their iPhone 2Georgia-Pacific Professional Brings Its Success in Medical Solutions to the Dental Community 2Georgia-Pacific Professional Brings Its Success in Medical Solutions to the Dental Community 3
... (Nasdaq: THOR ), a world leader in device-based ... hearts, today announced that it will report its operating results ... 2010 on Thursday, October 28. The company will ... operating activities open to all interested parties at 1:30 p.m., ...
... 22 Bacterin International Holdings, Inc. (OTC Bulletin ... is scheduled to present at the upcoming Singular Research 5th ... 2010 at 3:20p.m.(PT) at the Luxe Hotel Sunset Boulevard, Los ... Bacterin, and John Gandolfo, Bacterin,s chief financial officer, will review ...
Cached Medicine Technology:Thoratec Schedules Third Quarter Conference Call, Webcast 2Bacterin International to Present at Singular Research 5th Annual Best of the Uncovereds Conference 2
Used for the retrieval of stones, stents, or other objects in the urinary tract under direct vision. Retrieval Forceps are designed for use through rigid or flexible endoscopes. Supplied sterile in p...
... technology allows the grasper ... a shorter length and ... the stone. The Unidex ... one-handed operation. Supplied sterile ...
Bugbee Fulgurating...
Fulgurating Electrode, 2 F...
Medicine Products: