Navigation Links
Biologists discover 'control center' for sperm production
Date:2/2/2011

Biologists at the University of Leicester have published results of a new study into the intricacies of sex in flowering plants.

They have found that a gene in plants, called DUO1, acts as a master switch to ensure twin fertile sperm cells are made in each pollen grain.

The research identifies for the first time that DUO1 switches on a battery of genes that together govern sperm cell production and their ability to produce seeds..

The findings have implications for plant fertility, seed production and could be used to help produce improved crops to help meet food shortages. This work also formed part of one of the author's PhD thesis (Dr Michael Borg, University of Leicester).

The new study is reported in the journal The Plant Cell and was funded by the Biotechnology and Biological Sciences Research Council (BBSRC).

Professor David Twell and colleagues in the Department of Biology at the University of Leicester previously reported the discovery of a master regulator protein called DUO1 that has a critical role in allowing precursor reproductive cells to divide once to form twin sperm cells. The discovery of a battery of genes governed by DUO1 has shed light on the mechanisms by which plants control sperm cell formation and fertility.

Professor Twell said: "Unlike animals, flowering plants require not one, but two sperm cells for successful reproduction. These two sperm cells are housed within pollen grains, which act as a vehicle to deliver the sperm cells to the female sex cells within a flower.

"One sperm cell will join with the egg cell to produce the future plant or embryo, whilst the other will join with a second cell deep within the flower (the central cell) to produce a nutrient-rich tissue called the endosperm. Together these two structures make up the seeds and grains that form the staple food of humans and livestock across the globe.

"A mystery in this 'double fertilisation' event was how each pollen grain could produce the pair of sperm cells needed to make seeds. We now report that the regulatory gene DUO1 switches on a battery of genes that together govern sperm cell production and their ability to fuse with the egg and central cells. So in effect DUO1 acts as a master switch to ensure twin fertile sperm cells are made. "

Their new study expands on their previous work on pollen development and has identified a battery of new genes that collectively ensure male fertility in flowering plants.

The study of genes active within plant sperm is technically challenging because their sperm cells are not only tiny, but they are encased within tough pollen grains and as such are difficult to isolate. "We overcame this problem by genetically forcing plants to make DUO1 in plant roots, a place it is not normally found because DUO1 is normally restricted to sperm cells. By studying these genetically modified plants, we were able to survey the target genes switched on by DUO1."

The researchers also report on the mechanism by which DUO1 switches on its target genes. Being a regulatory protein, DUO1 was shown to bind to short DNA sequences near the genes that it targets, which in turn allows DUO1 to control a wide variety of processes needed for sperm cell production.

"This work provides insight into the genetic mechanisms by which fertile gamete production is achieved in flowering plants. Such knowledge will also be helpful in devising strategies for the targeted manipulation of sperm cells, enabling plant breeders to control crossing behaviour in crop plants." This work also provides new molecular tools for the manipulation of plant fertility and hybrid seed production as well the means to control gene flow in transgenic crops where the male contribution may need to be eliminated.

Professor Twell added that the study is timely given the challenges of breeding improved crops to meet the demands of food shortage and food price inflation the world is currently facing.


'/>"/>

Contact: David Twell
twe@le.ac.uk
44-116-252-2281
University of Leicester
Source:Eurekalert  

Related medicine news :

1. Physicists help biologists to understand protein folding
2. U. Iowa biologists publish findings on cell interactions
3. Caltech biologists discover microRNAs that control function of blood stem cells
4. Biologists, educators recognize excellence in evolution education
5. National Academy of Sciences honors microbiologists for major scientific contributions
6. Researchers discover new way to kill pediatric brain tumors
7. Scientists Discover How HIV Is Transmitted Between Men
8. First Gene Variants Linked to Stuttering Discovered
9. Researchers Who Discovered First Genes for Stuttering will Present Findings to the National Stuttering Association
10. Scientists Discover Molecular Pathway for Organ Tissue Regeneration and Repair
11. IU research team discovers TB disease mechanism and molecule to block it
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Biologists discover 'control center' for sperm production
(Date:6/27/2016)... ... June 27, 2016 , ... "FCPX editors can now reveal their media with ... X," said Christina Austin - CEO of Pixel Film Studios. , ProSlice Color ... users can now reveal the media of their split screens with growing colorful ...
(Date:6/27/2016)... ... June 27, 2016 , ... ... patient payment industry today announced its strategic partnership with Connance, a healthcare ... , The two companies’ proven, proprietary technology combine to provide health systems, ...
(Date:6/27/2016)... Park, KS (PRWEB) , ... June 27, 2016 , ... ... in retailers of Eyeglasses . , Millions of individuals in the United States ... eyeglasses have become a way to both correct vision and make a fashion statement. ...
(Date:6/26/2016)... Battle Creek, Michigan (PRWEB) , ... June 26, 2016 , ... ... abuse, joined as sponsor of the 2016 Cereal Festival and World’s Longest Breakfast Table ... held in honor of the city’s history as home to some of the world’s ...
(Date:6/26/2016)... ... ... PawPaws brand pet supplements owned by Whole Health Supply is ... of felines. The formula is all-natural and is made from Chinese herbs that have ... Kidney Support Supplement Soft Chews are Astragalus Root Extract and Rehmannia Root Extract ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , June 24, 2016 ... appointment of Dr. Edward Futcher to ... Director, effective June 23, 2016.Dr. Futcher was also ... and Governance Committees.  As a non-executive member of ... expertise and strategic counsel to VolitionRx in connection ...
(Date:6/23/2016)... June 23, 2016 Research and ... Excipients Market by Type (Organic Chemical (Sugar, Petrochemical, Glycerin), ... Topical, Coating, Parenteral) - Global Forecast to 2021" ... The global pharmaceutical excipients market is projected ... CAGR of 6.1% in the forecast period 2016 to ...
(Date:6/23/2016)... 23, 2016 Research and Markets has ... 52" report to their offering. ... creates a favourable commercial environment for MedImmune to enter. The ... that will serve to drive considerable growth for effective anti-influenza ... to cap sales considerably, but development is still in its ...
Breaking Medicine Technology: