Navigation Links
Biologists Discover How Dengue Virus Matures
Date:3/27/2008

Finding may aid efforts to treat other infections

THURSDAY, March 27 (HealthDay News) -- The way dengue virus matures and becomes infectious has been determined by biologists at Purdue University in Indiana.

The dengue virus, which is spread by mosquitoes, infects more than 50 million people a year and kills about 24,000, primarily in tropical regions. The virus is prevalent in Southeast Asia, Central America and South America.

The Purdue team identified important changes that occur as the virus is assembled and moves from the inner to the outer portions of a host cell before the virus is secreted and can infect other cells.

Virus particles are exposed to progressively less acidic conditions as they move along this "secretory pathway." The changing acidity plays a critical role in the maturation of the Dengue virus.

"This is possibly the most detailed understanding of how any virus matures," research co-author Michael Rossmann, a professor of biological sciences, said in a prepared statement.

He noted that there's been extensive research into pathways used by viruses to enter new host cells, but the way that viruses move out of host cells to infect other cells isn't well understood.

These findings, published in the March 28 issue of Science, pertain to all other flaviviruses, which include other dangerous insect-borne disease such as West Nile, yellow fever, and St. Louis encephalitis, the researchers said.

This research may help in efforts to find ways to treat or prevent viral infections.

More information

The U.S. Centers for Disease Control and Prevention has more about dengue fever.



-- Robert Preidt



SOURCE: Purdue University, news release, March 27, 2008
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved

Page: 1 2

Related medicine news :

1. First biomarker discovered that predicts prostate cancer outcome
2. Mayo Clinic researchers discover new diagnostic test for detecting infection in prosthetic joints
3. New prion protein discovered by Canadian scientists may offer insight into mad cow disease
4. Discovery of sugar sensor in intestine could benefit diabetes
5. Discovery suggests location of genes for breast density, a strong risk factor for breast cancer
6. Discover The Mutter Museum After Dark
7. Stem cell research produces a key discovery for Fragile X Syndrome
8. Welch Foundation gives $1.6 million for drug discovery research
9. Researchers discover correlation between GERD and obesity in females
10. New discovery leaves blood-doping athletes scratching their heads
11. Chemical Diversity Initiates International Prostrate Cancer Discovery Partnership
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/1/2015)... April 01, 2015 The Pennsylvania Court ... lawsuits ( http://www.risperdallawsuit2014.com/ ) has scheduled a meeting ... the Philadelphia Court of Common Pleas, the meeting will ... Hall. Court records indicate that the proceeding will address ... of Risperdal users who experienced gynecomastia (male breast growth) ...
(Date:4/1/2015)... Eagan, Minn. (PRWEB) April 01, 2015 ... Shield of Minnesota and its family of companies (Blue ... Cross closed out the year with net income of ... slight operational losses. The organization reported a net operating ... billion, for a negative operating margin of one-tenth of ...
(Date:4/1/2015)... 2015 Parents of teenaged and adolescent ... where the latest post discusses Teen Violence Related to ... Teen Dating Violence Awareness Month, the substance abuse treatment ... to help parents identify if there may be problems ... involve drugs or alcohol. , “People learn how to ...
(Date:4/1/2015)... 01, 2015 South Florida’s newest concept ... of Authority (PCOA) approval from the State of Florida. ... ongoing development of a retirement community that will offer ... and spiritual development. , America’s aging population is experiencing ... housing needs of seniors, according to a recent report ...
(Date:4/1/2015)... April 01, 2015 eMindful , ... expansion of its executive team with the addition of ... officer. , In his new role, Suissa ... user interface across the business and consumer portals. He ... building the company’s online community. His hiring was ...
Breaking Medicine News(10 mins):Health News:Pennsylvania Court Overseeing Hundreds of Risperdal Lawsuits Schedules April Meeting 2Health News:Pennsylvania Court Overseeing Hundreds of Risperdal Lawsuits Schedules April Meeting 3Health News:Blue Cross and Blue Shield of Minnesota Reports 2014 Results 2Health News:Blue Cross and Blue Shield of Minnesota Reports 2014 Results 3Health News:Best Drug Rehabilitation Issues Toolkit for Teen Violence Related to Substance Abuse 2Health News:Casa Sant’Angelo Receives Approval for New Retirement Living 2Health News:Addressing The Growing Demand for Interactive, Internet Mindfulness Programs, eMindful Expands Leadership Team With Top Digital Marketing Executive 2Health News:Addressing The Growing Demand for Interactive, Internet Mindfulness Programs, eMindful Expands Leadership Team With Top Digital Marketing Executive 3
... were cut by half to an average national rate of ... cases of lung cancer by 2030 and save $656 million ... platform developed for the Canadian Partnership Against Cancer and presented ... hosted by the International Association for the Study of Lung ...
... diseases (NCD), such as cardiovascular disease, diabetes, arthritis, chronic ... problem of the 21st century and affect all age ... and for many countries is an under-appreciated cause of ... Genome Medicine an international group of scientists ...
... 5 (HealthDay News) -- Healthy living significantly reduces a woman,s ... Researchers analyzed data from about 82,000 women who participated ... those 26 years, there were 321 cases of sudden cardiac ... died was 72. Four low-risk lifestyle factors were significantly ...
... HealthDay Reporter , TUESDAY, July 5 (HealthDay News) ... for easing low back pain in the short term, a ... mostly middle-aged, female and white, all of whom had chronic ... of either relaxation massage or structural massage were better able ...
... reduce colorectal cancer risk, according to a new study ... American Gastroenterological Association (AGA) Institute. Folate is a water-soluble ... found that all forms and sources of folate were ... Stevens, PhD, of the American Cancer Society and lead ...
... HealthDay Reporter , MONDAY, July 4 (HealthDay News) ... heart attacks and strokes by as much as 72 percent ... researchers say. The new study comes just over a ... small but significant risk of heart attack and stroke among ...
Cached Medicine News:Health News:Canada's Cancer Risk Management model is an important new health tool for policymakers 2Health News:Massage Beats Meds for Lower Back Pain, Study Says 2Health News:High folate intake may reduce risk of colorectal cancer 2Health News:Stop-Smoking Drug Chantix Ups Risk of Heart Problems: Study 2Health News:Stop-Smoking Drug Chantix Ups Risk of Heart Problems: Study 3Health News:Stop-Smoking Drug Chantix Ups Risk of Heart Problems: Study 4
(Date:4/1/2015)... and ASPEN, Colo. , April ... with the Chris Klug Foundation (CKF), is pleased to sponsor ... being accepted for the award, which will recognize two ... life, whether it is a career accomplishment, participation in ... life with family and loved ones. ...
(Date:4/1/2015)... , April 1, 2015 According ... (Neuro & Spine Surgery, Plastic and Reconstructive Surgery, Oncology, ... (Hospitals, Outpatient Facilities) - Global Forecast to 2020", published ... reach $806.6 Million by 2020 from $402.2 Million in ... 2020.. Browse   7 6 ...
(Date:4/1/2015)... INDIANAPOLIS , April 1, 2015 Eli Lilly ... results for the first quarter of 2015 on Thursday, April ... that day with the investment community and media to further ... will begin at 9:00 a.m. EDT. Investors, media, and the ... call through a link that will be posted on Lilly,s ...
Breaking Medicine Technology:Astellas Teams Up with The Chris Klug Foundation on the Bounce Back Award to Recognize Extraordinary Transplant Recipients 2Astellas Teams Up with The Chris Klug Foundation on the Bounce Back Award to Recognize Extraordinary Transplant Recipients 3Surgical Microscopes Market Worth $806.6 Million by 2020 2Surgical Microscopes Market Worth $806.6 Million by 2020 3Surgical Microscopes Market Worth $806.6 Million by 2020 4Lilly Confirms Date and Conference Call for First-Quarter 2015 Financial Results Announcement 2
... the launch of its new depot service for Agilent ... to BioSurplus for repair and preventative maintenance by trained ... major cost savings to customers outside of biotech hubs ... An introductory 15% discount on preventative maintenance services ...
... 8, 2012  Insmed Incorporated (Nasdaq: INSM ), a ... March 31, 2012. Key Recent Highlights: ... hold on ARIKACE® (liposomal amikacin for inhalation) in Cystic Fibrosis ... Initiated dosing in CL inical E valuation of ...
Cached Medicine Technology:BioSurplus Announces Launch of Depot Service for Agilent and AKTA HPLCs 2Insmed Announces First Quarter 2012 Financial Results 2Insmed Announces First Quarter 2012 Financial Results 3Insmed Announces First Quarter 2012 Financial Results 4Insmed Announces First Quarter 2012 Financial Results 5Insmed Announces First Quarter 2012 Financial Results 6Insmed Announces First Quarter 2012 Financial Results 7
The major innovation in posterior stabilized (PS) knee design. Improve patellofemoral kinematics. Reduce wear rate potential. Increase resistance to posterior tibial dislocation. Achieve at least 120...
... knee replacement is an exciting development in ... provides patients with a minimally invasive solution ... knee often results in severe pain, loss ... and even depression. Orthopedic surgeons have worked ...
... tricompartmental total knee prosthesis stems from many ... design and manufacturing technologies have been used ... as well as a favorable pressure distribution ... keep wear to a minimum. The inherent ...
Cemented hip system...
Medicine Products: