Navigation Links
Biological markers of prostate cancer shed light on cancer burden faced by African-American men
Date:11/29/2007

ATLANTA -- Researchers based at Tulane University report the discovery of biological markers of prostate cancer which are involved in the growth of tumor cells, shedding light on the genetic basis for the prostate cancer burden faced by African-American men. The research is being presented today at the American Association for Cancer Research conference on The Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved, being held November 27-30.

In prostate tumors samples taken from African-American and Caucasian men, the researchers found that two proteins are overproduced in 90 percent of tumor cells from the African-Americans studied. These structural proteins, called hnRNP-H1 and SAFB-2, in part comprise the nuclear matrix, the mesh of molecules that serves as the supporting skeleton of the cells nucleus.

We have employed a unique functional genomics approach to unravel the molecular mechanisms underlying the disproportionate incidence and mortality among African-American men, said Asim B. Abdel-Mageed, D.V.M, Ph.D., associate professor and director of the Molecular Oncology Research program in the Department of Urology at Tulane University School of Medicine.

Currently, prostate specific antigen (PSA) and digital rectal examinations are the two most common methods of detecting prostate cancer. African Americans are typically diagnosed with prostate cancer more frequently and later when the cancer is at an advanced stage and more aggressive than any other ethnic group in the United States. According to Abdel-Mageed, earlier detection of prostate cancer might decrease this health disparity. The target genes may have potential clinical utility as biomarkers or prognostic indicators of disease progression in African-American men independent of a PSA screen, Abdel-Mageed said.

With funding from the National Cancer Institute and American Cancer Society, the researchers compared prosta
'/>"/>

Contact: Greg Lester
greg.lester@aacr.org
267-646-0554
American Association for Cancer Research
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Thomson Scientific Announces BONDplus for Biological Researchers
2. Neurobiological Technologies Reports Going Concern Qualification
3. Neurobiological Technologies, Inc. Announces Receipt of Determination Letter from NASDAQ
4. Study questions assumptions about human sensitivity to biological motion
5. Neurobiological Technologies Reports $2.1 Million Quarterly Payment for Sales of Memantine
6. Neurobiological Technologies Announces Compliance With Nasdaq Listing Standards
7. Dr. Warren Wasiewski Appointed Chief Medical Officer of Neurobiological Technologies, Inc.
8. UCLA researchers identify markers that may predict diabetes in still-healthy people
9. Penn School of Medicine receives $2.3 million to study biomarkers of cigarette smoke exposure
10. Study makes progress in zoning in on biomarkers for better colon cancer treatment
11. Study shows blood markers can help choose best dose for antiangiogenic drugs
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/1/2015)... ... September 01, 2015 , ... Stress comes ... created from everyday life changes can lead to very serious, life-altering events. Fortunately ... coping with stress. Herbal supplement manufacturer MediHerb has coupled therapeutic doses ...
(Date:9/1/2015)... ... 01, 2015 , ... From Aug. 17-21, Calvary Hospital hosted the 18th consecutive ... Camp Compass® has taken place at Kingsborough Community College in Brooklyn in each of ... work for Calvary, and two junior counselors who were campers themselves just a few ...
(Date:9/1/2015)... ... September 01, 2015 , ... Horizon Blue Cross Blue Shield of ... for Latinas in the LATINA Style 50 Report that recognizes companies that provide the ... For 2015, Horizon BCBSNJ climbs from number 24 to 21 of the 50 Best ...
(Date:9/1/2015)... , ... September 01, 2015 ... ... better therapeutic options to efficiently cure and prevent different malignancies. Some options ... have different pathophysiological properties due to which distinctive approach is necessary for ...
(Date:9/1/2015)... ... September 01, 2015 , ... ... Blue Cross and Blue Shield of Minnesota (Blue Cross) has announced Doctor On ... Based in San Francisco, Doctor On Demand provides immediate access to Board Certified ...
Breaking Medicine News(10 mins):Health News:MediHerb Launches New Herbal Supplement to Help with the Challenges of Everyday Life 2Health News:MediHerb Launches New Herbal Supplement to Help with the Challenges of Everyday Life 3Health News:Calvary Hospital Hosts 18th Annual Bereavement Camp 2Health News:Calvary Hospital Hosts 18th Annual Bereavement Camp 3Health News:Horizon Blue Cross Blue Shield of New Jersey Named One of the 50 Best Companies for Latinas by Latina Style Magazine 2Health News:Horizon Blue Cross Blue Shield of New Jersey Named One of the 50 Best Companies for Latinas by Latina Style Magazine 3Health News:CD Antigen Cancer Market and Pipeline Landscape Examined in Comprehensive Kuick Research Report Published at MarketPublishers.com 2Health News:CD Antigen Cancer Market and Pipeline Landscape Examined in Comprehensive Kuick Research Report Published at MarketPublishers.com 3Health News:Blue Cross and Blue Shield of Minnesota names Doctor On Demand as preferred telehealth destination 2Health News:Blue Cross and Blue Shield of Minnesota names Doctor On Demand as preferred telehealth destination 3
... polymer, fitted with molecular pincers of carefully tailored structure, ... can be used for fabrication of sensitive and selective ... the near future also in gases. Moreover, the polymer ... for therapeutic purposes. The collaboration of researchers of ...
... tripled in the United States between 1999 and 2006, ... heroin overdoses combined. Hospitalizations and emergency room visits related ... name Oxycontin) and hydrocodone (Vicodin) also increased dramatically in ... the August issue of Health Affairs describes ...
... Goodwin HealthDay Reporter , WEDNESDAY, Aug. 3 ... certain markers in the blood called "autoantibodies" is showing ... blood test correctly detected Alzheimer,s disease in people already ... accuracy, according to the researchers. The test could also ...
... Society of America (GSA) the nation,s largest interdisciplinary organization ... Ferraro, PhD, of Purdue University as the 2011 recipient of ... given to individuals who have not only fostered excellence in ... of their mentoring, and whose inspiration is sought by students ...
... A Mayo Clinic orthopedic surgeon suspects that the nagging ... knees may be different from what men encounter, and ... study to explore the question. The Society for Women,s ... (ISIS) Network on Musculoskeletal Health has awarded a group ...
... Scientists at Cold Spring Harbor Laboratory (CSHL) and five other ... to identify a new potential treatment for acute myeloid leukemia ... 3, the scientists have pinpointed a protein called Brd4 as ... that is currently incurable in 70% of patients. Using a ...
Cached Medicine News:Health News:Polymer's hunt for nicotine 2Health News:Polymer's hunt for nicotine 3Health News:Group Health establishes major initiative to prevent opioid abuse and overdose 2Health News:Group Health establishes major initiative to prevent opioid abuse and overdose 3Health News:Another Blood Test for Alzheimer's Shows Promise 2Health News:Another Blood Test for Alzheimer's Shows Promise 3Health News:Another Blood Test for Alzheimer's Shows Promise 4Health News:Ferraro to receive GSA's 2011 Distinguished Mentorship in Gerontology Award 2Health News:Mayo Clinic examines why knee osteoarthritis afflicts more women than men 2Health News:Unconventional hunt for new cancer targets leads to a powerful drug candidate for leukemia 2Health News:Unconventional hunt for new cancer targets leads to a powerful drug candidate for leukemia 3Health News:Unconventional hunt for new cancer targets leads to a powerful drug candidate for leukemia 4
(Date:9/1/2015)... TAIPEI , Sept. 1, 2015 ... (GNTbm) held a press conference in Taipei ... developments in its new Vaucarrin™ platform, a targeted drug ... vehicle. This event was part of a ... Gold NanoTech Inc. (GNT), showcasing GNT,s latest ...
(Date:9/1/2015)... Sept. 1, 2015 Sargas Pharmaceutical Adherence ... and Drug Adherence m Health applications along with ... process of non face-to-face monitoring of twenty minutes ... release of our apps, doctors are now well ... with our ONCHIT certified Physician, Pharmacy and Patient ...
(Date:9/1/2015)... -- Agena Bioscience TM today announced the establishment of ... and financial hub from which many biotech and life science ... mainland China . "The Chinese ... with almost sixty MassARRAY ® Systems installed to date. ... us to expand our reach and foster a high degree ...
Breaking Medicine Technology:GNTbm Updates Developments in the Vaucarrin(TM) annogold Drug Delivery Platform 2GNTbm Updates Developments in the Vaucarrin(TM) annogold Drug Delivery Platform 3GNTbm Updates Developments in the Vaucarrin(TM) annogold Drug Delivery Platform 4GNTbm Updates Developments in the Vaucarrin(TM) annogold Drug Delivery Platform 5SPAC International's Drug Adherence and Chronic Care Management App Now available at Apple App and Google Play stores 2Agena Bioscience Opens Office in Shanghai, China 2
... 12 Research presented at the American College of ... that an intervention to reduce over-dispensing and waste of ... can result in substantial cost savings. , Medco Health ... of a study that examined the effectiveness and safety ...
... 12 /PRNewswire / -- New research findings ... (SIO) Sixth International Conference in New York show ... complementary and alternative medicine (CAM) using traditional research ... Children,s Hospitals and Clinics of Minnesota (Children,s), presented ...
Cached Medicine Technology:New Research Shows Over-use of Asthma Rescue Inhalers Substantially Reduced Through Pharmacist-initiated Physician Intervention 2New Research Shows Over-use of Asthma Rescue Inhalers Substantially Reduced Through Pharmacist-initiated Physician Intervention 3New Research Shows Promise in Using Traditional Research Methods to Assess Efficacy of Complementary Therapies 2
Straight shafts with 0.12 mm teeth and tying platform. Serrated handle with polished finish....
Angled 45 degree shafts with 1 x 2 teeth and 5 mm tying platform. Serrated handle with dull finish....
Heavy curved shafts with 2 x 2 teeth and crisscross serrated 6 mm tying platform. Serrated handle with polished finish....
Straight shafts with 1 x 2 teeth and 6 mm tying platform. Wide serrated handle with polished finish....
Medicine Products: