'Biological clock' could be a key to better health, l... (sleep to jet lag or working the swing sh...)

'Biological clock' could be a key to better health, longer life

Date:3/1/2010

sleep to jet lag or working the swing shift. The study used some normal fruit flies and other mutant flies in which the "period" gene was absent.

The work was done under the leadership of Jadwiga Giebultowicz, an OSU professor of zoology, in collaboration with Dr. Doris Kretzschmar from the Oregon Health and Sciences University. The research was supported by the National Institutes of Health and the Oregon Partnership for Alzheimer's Research.

In control studies, the mutant flies with no functional "period" gene lived just about as long as normal flies, unless they were stressed. In experiments, researchers caused a mild metabolic stress an elevated level of reactive oxygen species for 24 hours to the flies at various times, which corresponded to their youth, middle age and old age. There was no significant change in the young flies. But in middle-age and older flies, significant damage began to occur.

Mutant flies lost some of their motor ability to climb, and morphologic examinations of their brains showed higher levels of neuronal degeneration, similar to neurodegenerative diseases such as Alzheimer's disease in humans. When exposed to a single stressful event in "middle age," the mutant flies had a 12 percent shorter lifespan than normal flies exposed to the same stress. And when exposed to a single stress in old age, their lifespan was 20 percent shorter.

The study concluded that expression of the "period" gene naturally declines with age. If the same is true for humans, that could help explain why people may lose some of their ability to handle oxidative and other stresses at a time of their life when they need it most.

The scientists theorized that the "period" gene is regulating pathways involved in removal of oxidative damage, and those without this function experienced the symptoms of aging more quickly. This could ultimately have impacts on everything from neurological damage to heart disease and cancer.

Contact: Natraj Krishnan
krishnan@science.oregonstate.edu
541-737-5513
Oregon State University
Source:Eurekalert

0

GOOD

Page: 1 2 3
Related medicine news :

1. Study carried out into biological risks of eating reptiles
2. Biological catch-22 prevents induction of antibodies that block HIV
3. Launch of ImmortalHumans.com as a Result of Humankind's Drive to Cure Aging and Become Biologically Immortal Within this Century
4. New and Updated Online Tutorials for PID, BiologicalNetworks, and Cytoscape
5. Studies in animals suggest 2009 H1N1 virus may have biological advantage over seasonal influenza
6. Special Stem Cells Build Biological Bypass
7. Stem Cells Used for Biological Pacemaker
8. Cancer Gap Between Whites, Blacks May Be Biological in Part
9. UGA researchers achieve breakthrough in effort to develop tiny biological fuel cells
10. Video: New Biological Therapy Ilaris(R) Approved in US to Treat Children and Adults with CAPS, a Serious Life-Long Auto-Inflammatory Disease
11. Neurobiological Technologies Reports Third Quarter Fiscal 2009 Financial Results

Post Your Comments:

(Date:5/21/2013)... The producers of Net Worth Business TV ... Ontario, Canada. The area is famous for its natural beauty ... It is located an hour from Toronto and is easily ... the Kawartha Hills, home to several towns, villages and hamlets ... area. Residents and visitors to this region will be able ...

(Date:5/21/2013)... (PRWEB) May 21, 2013 Five million ... For those who do, Tiffany Liashek, owner of ... advice. “Take a long look at credentials and experience. ... is huge,” she says. “A trainer can pay $69.50 ... scares me.” , Good trainers invest in themselves, A ...

(Date:5/21/2013)... Delmar, NY (PRWEB) May 21, 2013 ... announce the release of his first two barbering DVDs. ... viewers are enrolled barber school , cosmetology school ... the opportunity to learn from an experienced teacher and ... in classic barbering from the 1920’s – 1960’s time ...

(Date:5/21/2013)... 2013 Dallas-based TopMD™ Skin Care today ... testing the efficacy of their flagship product, CLn® ... study results appear in the May/June 2013 issue of ... Novel Sodium Hypochlorite Cleanser Shows Clinical Response and Excellent ... findings seen after consistent use of the product by ...

(Date:5/21/2013)... (PRWEB) May 21, 2013 Everspark Interactive, ... firms, has been growing rapidly over the past year ... was hired to spearhead interactive marketing efforts for Kids ... , Everspark started as a local effort, specializing ... guiding search traffic to a company's website. The company ...

Breaking Medicine News(10 mins):Health News:Net Worth Business TV Announces May Air Dates for Peterborough, Ontario 2 Health News:Sarasota Fitness Tips: Choosing a Safe Trainer and Gym 2 Health News:Sarasota Fitness Tips: Choosing a Safe Trainer and Gym 3 Health News:First Series of Barbering DVDs Launched by Third Generation Master Barber Greg Zorian; DVDs Teach the Art of Men's Haircutting, Clipper Cutting, Fades and More 2 Health News:First Series of Barbering DVDs Launched by Third Generation Master Barber Greg Zorian; DVDs Teach the Art of Men's Haircutting, Clipper Cutting, Fades and More 3 Health News:First Series of Barbering DVDs Launched by Third Generation Master Barber Greg Zorian; DVDs Teach the Art of Men's Haircutting, Clipper Cutting, Fades and More 4 Health News:First Series of Barbering DVDs Launched by Third Generation Master Barber Greg Zorian; DVDs Teach the Art of Men's Haircutting, Clipper Cutting, Fades and More 5 Health News:First Series of Barbering DVDs Launched by Third Generation Master Barber Greg Zorian; DVDs Teach the Art of Men's Haircutting, Clipper Cutting, Fades and More 6 Health News:Peer-Reviewed Article Shows CLn® BodyWash an Effective Solution for Children with Eczema 2 Health News:Peer-Reviewed Article Shows CLn® BodyWash an Effective Solution for Children with Eczema 3 Health News:Everspark Named Interactive Marketing Company for Kids II 2

[0] Net Worth Business TV Announces May Air Dates for Peterborough, Ontario [0] Sarasota Fitness Tips: Choosing a Safe Trainer and Gym [0] First Series of Barbering DVDs Launched by Third Generation Master Barber Greg Zorian; DVDs Teach the Art of Men's Haircutting, Clipper Cutting, Fades and More [0] Peer-Reviewed Article Shows CLn® BodyWash an Effective Solution for Children with Eczema [0] Everspark Named Interactive Marketing Company for Kids II

... CITY, Calif., Sept. 30 Genomic Health, Inc. ... Health,s Chief Operating Officer and Chief Financial Officer, will present ... City, on Tuesday, October 6 at 9:30 a.m. ET. ... the presentation, visit the Investor Relations section of Genomic Health,s ...

... October is National Breast Cancer Awareness Month and Topcor is ... , Available October 5th, "Clipa for a Cure" is a ... Topcor will donate 10% of the retail price of every ... American Cancer Society, breast cancer is the second leading cause ...

... ... that they now help physicians find jobs on Twitter by using the popular social ... providers. , ... CO (PRWEB) September 29, 2009 -- Onyx M.D., a Denver, Colorado-based physician recruiting company, ...

... ... live. Everyone, including doctors, administrators, nurses, et al, are encouraged to go online to ... ... first multi-disciplinary, online healthcare community. It is designed for everyone in the medical field ...

... The American Federation of Government Employees expresses grave concern at the ... would be rising by an average of 8.8% in 2010. ... for 60% of the enrollees in FEHBP, those covered by Blue ... by 15% for self coverage and 12% for family coverage. ...

... PARSIPPANY, N.J., Sept. 30 Thousands of bacteria lurk ... hygiene routines to help protect themselves from serious illness, ... College Center for Hygiene and Health in Home and ... products.(1) Despite growing concerns about influenza A (H1N1) on ...

Cached Medicine News:Health News:'Clipa for a Cure': New Pink Instant Handbag Hanger Benefits Breast Cancer Research 2 Health News:Onyx M.D. Now Tweet Jobs for Physician Job Opportunities by Specialty 2 Health News:Onyx M.D. Now Tweet Jobs for Physician Job Opportunities by Specialty 3 Health News:Online Healthcare Community, TogetherMD, is Live 2 Health News:Study Shows College Students Are Not Following CDC Recommendations to Help Protect Themselves from H1N1 and Other Threatening Germs 2 Health News:Study Shows College Students Are Not Following CDC Recommendations to Help Protect Themselves from H1N1 and Other Threatening Germs 3 Health News:Study Shows College Students Are Not Following CDC Recommendations to Help Protect Themselves from H1N1 and Other Threatening Germs 4 Health News:Study Shows College Students Are Not Following CDC Recommendations to Help Protect Themselves from H1N1 and Other Threatening Germs 5

Genomic Health to Present at the JMP Securities Healthcare Focus Conference 'Clipa for a Cure': New Pink Instant Handbag Hanger Benefits Breast Cancer Research Onyx M.D. Now Tweet Jobs for Physician Job Opportunities by Specialty Online Healthcare Community, TogetherMD, is Live AFGE Expresses Concern Over FEHBP Premium Increases Study Shows College Students Are Not Following CDC Recommendations to Help Protect Themselves from H1N1 and Other Threatening Germs

(Date:5/21/2013)... 2013 The North Shore-LIJ Health System is expanding ... compliance at North Shore University Hospital in ... rooms at Forest Hills (NY) ... The new pilot program strengthens patient safety by providing ... the first time in the US that remote video ...

(Date:5/21/2013)... , May 21, 2013 ... report is available in its catalogue: ... and Technologies for Optical Coherence Tomography (OCT) ... STUDY OBJECTIVES ... study is to offer synopsis of the ...

(Date:5/21/2013)... , May 21, 2013 Healthcare organizations expanding into ... Russia , India ... there are no shortcuts. This is proving particularly challenging, ... States. Companies must change the dialogue around BRIC, as ... local needs, and building regional partnerships to build a ...

[0] North Shore-LIJ Extends Use of 3rd Party Remote Video Auditing into ORs [0] Global Markets and Technologies for Optical Coherence Tomography (OCT)[0] Frost & Sullivan: BRIC is Not Delivering Promises of High Growth in Healthcare Markets

... ,, NEW YORK , May 12 Reportlinker.com announces that a new market ... , Antifungal Drugs: Technologies and ... http://www.reportlinker.com/p0196570/Antifungal-Drugs-Technologies-and-Global-Markets.html , ... , , , ...

... 11 Stereotaxis, Inc. (Nasdaq: STXS ) today announces the ... Navigation platform that facilitates remote manipulation of diagnostic devices used during electrophysiology ... at the HRS meeting this week, and will be commercially available when ... , , ...

Reportlinker Adds Antifungal Drugs: Technologies and Global Markets Stereotaxis Announces Vdrive(TM), a New Technology for Remote Navigation of Diagnostic Devices

Inquire...

...

VACUETTE Trace Element tubes - Ridged (safety screw cap) are designed to test trace elements such as Cu, Zn, Pb, etc....

Inquire...

Medicine Products:

MONOJECT Royal Blue Stopper (No Additive)MONOJECT Royal Blue Stopper (Powdered Additive)VACUETTE Trace Element tubes - Ridged (safety screw cap)MONOJECT Red Stopper (Silicone Coated Tube)