Navigation Links
Bioengineered Skin Grafts Control Blood Pressure in Mice
Date:1/16/2010

up to use in larger animals. That question still has to be answered."

Other questions are the duration of the effect (because as Vogel noted, "these were fairly short-term studies"), and how many other conditions the technique might be used to treat.

"One other condition we are talking about is anemia," Vogel said. "That has been actively thought of in our laboratory. But that is far in the future. It would require much tighter regulation than we now can achieve."

And while this was "a first step in a small animal model," a point has been proven, he added.

"It shows we can engineer a skin graft, can graft it successfully, and that the product that the skin cells make gets access to the bloodstream, which is not trivial. It gets there in sufficient levels to have a biological effect," Vogel said.

Dorothy Supp, an associate investigator at Shriner's Hospital for Children in Cincinnati and adjunct research professor in the University of Cincinnati's department of surgery, who has her own research project using modified skin cells, called the new study "very exciting."

"My work involves generating modifications in skin cells to improve healing," Supp said. Like Vogel, she uses a retrovirus to modify the cells. "What we would like to do is increase the expression of beneficial genes and decrease the expression of harmful ones," she said.

Skin graft therapy is nearing medical application after 20 years of effort, Supp explained. "The skin is a model system for gene therapy, and the fact that you can put a small graft on an animal and get a systemic response is very exciting," she said.

More information

The U.S. National Library of Medicine has more on skin grafts.



SOURCES: Jonathan Vogel, M.D., senior investigator, dermatology branch, U.S. National Canc
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved

Page: 1 2 3

Related medicine news :

1. Reconstructing mandibular defects with bioengineered tooth and bone
2. Bioengineered proteins: Trial confirms new way to tackle cancer
3. Natural aorta grafts have few side effects for infection-prone patients
4. RTI Biologics Sees Expanded Surgeon User Base of Fresh OC Allografts
5. Drug Combo Keeps Kidney Artery-Vein Grafts Viable
6. Reportlinker Adds World Bone Grafts Market Report
7. Bodys own veins provide superior material for aortic grafts
8. Chromatin remodeling complex connected to DNA damage control
9. More than two-thirds of sexually active NYC youth use condoms, but other forms of birth control lag
10. New Asthma Guidelines Stress Disease Control
11. UI nursing researcher to study post-operative pain control
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/30/2014)... comes to heart disease, a new study finds women are ... symptoms that spell trouble. "The main danger is that ... or advanced stage of heart disease, there are simply fewer ... and research fellow at the Harvard School of Public Health, ... Foundation of Canada. In the study, researchers talked to ...
(Date:10/30/2014)... Amy Norton HealthDay Reporter ... a common plastics, chemical during pregnancy may have effects on ... Researchers found that baby boys born to moms with greater ... shorter anogenital distance -- the space between the genitals and ... considered a marker of exposure to androgens ("male" hormones) during ...
(Date:10/30/2014)... Many U.S. colleges have indoor tanning salons on ... risk for skin cancer, researchers report. Tanning ... so colleges should adopt tanning-free policies, to help ... health efforts are needed to raise university administration ... indoor tanning poses to young adults in order ...
(Date:10/30/2014)... opinions about the Affordable Care Act are sharply divided ... voters are strongly in favor of the Affordable Care ... Democrats want the next Congress to move ahead with ... current law, while 44 percent want to expand the ... want the law repealed, and 27 percent want it ...
(Date:10/30/2014)... respects the fact that a patient,s body is ... Over a third of cancer patients experience psychosocial ... conditions. And, increasingly, care providers are exploring phone- ... mental health challenges. A University of Colorado Cancer ... Psycho-Oncology asks an important question: after decades ...
Breaking Medicine News(10 mins):Health News:Women Often Ignore Signs of Heart Trouble 2Health News:Plastics' Chemical May Affect Baby Boys' Genital Development 2Health News:Plastics' Chemical May Affect Baby Boys' Genital Development 3Health News:Many U.S. Colleges Have Indoor Tanning Salons On, Near Campus: Study 2Health News:Voters' Views on Obamacare Split Along Party Lines 2Health News:Decades of research: Effectiveness of phone counseling for cancer patients still unknown 2
... day to analysis and expert thought, they may be able ... of the precise type of brain tumour they face. Now ... technique that can give a preliminary analysis of the precise ... the brain and nervous system and they account for 20% ...
... Rosemont, Ill. - June 17, 2008- Current protein recommendations ... newer research indicates that many adults may benefit from ... presented in a supplement in the May issue of ... describing the conclusions of a Protein Summit ...
... on invasion and migration in colorectal cancer cell line. This ... performed by a team led by Professor Ji-Kun Li from ... article to be published on April 21, 2008 in the ... of the main causes of cancer-related death in the world. ...
... 17 XTENT, Inc.,(Nasdaq: XTNT ) today announced ... the current issue of EuroIntervention was recognized by the,journal,s ... submitted to the,journal this past winter. Lutz Buellesfeld, M.D., ... of the study,s investigators, received,an award in conjunction with ...
... Ala., June 17 Emageon Inc.,(Nasdaq: EMAG ... for hospitals, healthcare networks and imaging facilities announced,today ... present at the,Jefferies 2nd Annual Healthcare Conference on ... 24th at 8:30 AM ET. The presentation will ...
... 17 Nutrition 21, Inc.,(Nasdaq: NXXI ), ... consumers manage blood sugar levels, improve cardiovascular health,enhance ... Skin,Rejuvenation(TM) a new Iceland Health-branded product. Skin Rejuvenation ... capsule form,designed to reduce, at the cellular level, ...
Cached Medicine News:Health News:Wavelets crunch through doctors' day long struggle to diagnose brain tumors 2Health News:Is it time to revisit the current protein recommendations? 2Health News:Is it time to revisit the current protein recommendations? 3Health News:XTENT Announces CUSTOM I Data Receives Recognition from EuroIntervention 2Health News:XTENT Announces CUSTOM I Data Receives Recognition from EuroIntervention 3Health News:Nutrition 21 Introduces New Product: Iceland Health Skin Rejuvenation(TM) 2Health News:Nutrition 21 Introduces New Product: Iceland Health Skin Rejuvenation(TM) 3
(Date:10/30/2014)... , Oct. 30, 2014 Boston Scientific ... participate in the 2014 Credit Suisse Annual Healthcare Conference ... , AZ.  Dan Brennan , executive vice ... about the company beginning at approximately 8:00 a.m. PT ... A live webcast of the presentation and question and ...
(Date:10/30/2014)... -- CVS Health (NYSE: CVS ) announced today ... regional health systems to enhance access to high-quality, affordable health ... Health System in Alabama ; Community Health ... Pennsylvania , Northwest Medical Center, including Oro Valley ... in Tennessee ; and Premier Health in ...
(Date:10/30/2014)... , Oct. 30, 2014   BioLife Solutions ... developer, manufacturer and marketer of proprietary clinical grade ... and precision thermal shipping products for cells ... quarter 2014 financial results will be released on Thursday, ... a conference call and live webcast at 1:30 p.m. ...
Breaking Medicine Technology:Boston Scientific To Participate In 2014 Credit Suisse Annual Healthcare Conference 2CVS Health Announces New Clinical Affiliations with Leading Regional Health Systems 2CVS Health Announces New Clinical Affiliations with Leading Regional Health Systems 3CVS Health Announces New Clinical Affiliations with Leading Regional Health Systems 4BioLife Solutions to Report Financial Results for Third Quarter 2014 and Provide Business Update on November 6, 2014 2
... Aug. 22, 2011 Reportlinker.com announces ... is available in its catalogue: ... Strategic Assessments of Leading Suppliers ... This report provides diagnostic imaging ...
... Santosh Nanda, Microbiologist/ Primary Reviewer, CBER, FDA ... have announced their official participation at the Viral ... the 17th October to 19th October 2011 in NH ... has expanded its focus from solely viral safety to ...
Cached Medicine Technology:Global X-Ray Equipment Market: Strategic Assessments of Leading Suppliers 2Global X-Ray Equipment Market: Strategic Assessments of Leading Suppliers 3Global X-Ray Equipment Market: Strategic Assessments of Leading Suppliers 4Global X-Ray Equipment Market: Strategic Assessments of Leading Suppliers 5Food and Drug Administration (FDA) Joins Pharma IQ's Viral Safety 2011 Conference 2
... The E-Holder™ Platform is designed with a ... 96 and E-Gel® 48 gel cassettes stay ... allows reproducible placement and loading from one ... make adjustments to the robot loading software. ...
... seamless eliminating the possibility of leakage around glued ... temperature resistant gel trays meaning you do no ... added user friendliness, the Primo tanks come with ... The Primo Gel Systems are designed to be ...
Designed for rapid, routine electrophoresis for nucleic acids. The Mini unit is designed with a choice of two casting systems: standard casting trays that require sealing tape; or aluminum-gated cast...
... gel system is designed for very fast and clear ... System allows the user to cast, run, and perform ... with : 1 x electrophoresis tank and cover, 1 ... 83 mm tray), 2 x MT-T02 (50 x 60 ...
Medicine Products: