Navigation Links
Biodegradable stent proves non-inferior to drug-eluting stent
Date:5/21/2013

21 May 2013, Paris, France: The Orsiro stent, which is a novel stent platform eluting sirolimus from a biodegradable polymer, demonstrated non-inferiority to the Xience Prime everolimus-eluting stent for the primary angiographic endpoint of in-stent late lumen loss at nine months in the results of an imaging substudy reported at EuroPCR 2013 today.

The BIOFLOW-II substudy used intravascular ultrasound (IVUS) and optical coherence tomography (OCT) to quantitatively assess neointimal hyperplasia and stent apposition at nine months after treating patients with symptomatic coronary artery disease due to de novo stenotic lesions. Patients were randomly assigned to receive either the Orsiro (Biotronik) or the Xience Prime stent (Abbott Vascular). Images from baseline and the nine-month follow-up were analysed by independent and blinded core laboratories.

Results showed no difference in the angiographic endpoint of in-stent late lumen loss between the two stents at nine months (0.10+0.32mm with the Orsiro stent vs. 0.11 + 0.29mm with the Xience Prime stent, p non-inferiority=<0.0001). Rates of target lesion failure were also similar at nine months (4.8% vs. 5.3%, p=0.47).

The IVUS substudy showed somewhat less neointimal hyperplasia over nine months with the Orsiro stent (0.16) than the Xience stent (0.43, p=0.043) with 100% stent apposition. 
Similarly, neointimal area as assessed by OCT at nine months was somewhat less with the Orsiro stent (0.74+0.38mm2 ) than with the Xience stent (1.00+0.44mm2, p=0.024). The proportion of well-apposed struts was similar with the two stents and the proportion of covered struts was slightly higher with the Orsiro stent (98.3% vs. 97.5%, p=0.042).

Reporting the results, Stephan Windecker, Professor and Chief of Cardiology, Swiss Cardiovascular Center and Clinical Trials Unit Bern, Bern University Hospital, Switzerland, said, "The Orsiro sirolimus-eluting stent with a biodegradable polymer was
'/>"/>

Contact: Isabelle Uzielli
iuzielli@europcr.com
33-612-233-492
European Society of Cardiology
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Experiencing existential dread? Tylenol may do the trick
2. Scientists identify gene that is consistently altered in obese individuals
3. Metal stents are effective treatment for blocked bile ducts
4. Brain stent offers alternative to shunt for fixing potentially blinding vein narrowing
5. Scores that evaluate newborn intensive care units are inconsistent
6. Students in Educational First Steps Assisted Centers Show Persistent Benefits Far Beyond Early Childhood According to University of Texas at Dallas Study
7. Personal epigenetic signatures found consistent in prostate cancer patients metastases
8. Patient expectations of acute bronchitis not consistent with the best evidence
9. RSNA: New Study Finds Brain Angioplasty and Stents Safe and Effective for Stroke Patients
10. Study Supports Use of Brain Stents for Certain Stroke Patients
11. Brain angioplasty and stents found safe and effective for stroke patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/1/2014)... Permanent atrial fibrillation (AF) doubles the risk of stroke ... than 6 000 patients presented at ESC Congress today ... that a simple clinical assessment of the type of ... , Ischaemic stroke is the second cause of death ... and many more disabled patients each year. Annual direct ...
(Date:9/1/2014)... York (PRWEB) September 01, 2014 ... retrieve, organize and analyze biological and genetic data. ... the activity of developing software tools to generate ... to be confused with biological computation. While bioinformatics ... understanding of biology can its related concepts, biological ...
(Date:9/1/2014)... Top10BestSEOHosting.com has recently compared many web ... carefully, Top10BestSEOHosting.com is here to announce that JustHost, ... suppliers in 2014. , JustHost ( http://www.justhost.com/track/seohosts ) ... shared hosting plan. The company’s approach to hosting ... affordable, accessible and powerful enough for anyone to ...
(Date:9/1/2014)... San Diego, CA (PRWEB) September 01, 2014 ... website daily regarding all the latest information from the ... , The US FDA announced on August 28, ... are recalled (Class I) as the device ... FDA, the DePuy Synthes Craniomaxillofacial (CMF) Distraction System is ...
(Date:9/1/2014)... Mahwah, NJ (PRWEB) September 01, 2014 ... disorder (NEAD) is a psychological disorder that can have ... look very much like epileptic seizures however, they are ... rather by emotional triggers. It is estimated that ... than those affected by multiple sclerosis. , ...
Breaking Medicine News(10 mins):Health News:Permanent AF doubles risk of stroke compared to paroxysmal AF 2Health News:Bioinformatics Market: A fusion of Computers and Biological Data 2Health News:Bioinformatics Market: A fusion of Computers and Biological Data 3Health News:Bioinformatics Market: A fusion of Computers and Biological Data 4Health News:Why Top10BestSEOHosting.com Calls Them Great Web Hosting Suppliers 2Health News:DePuy Synthes Craniomaxillofacial Distraction System Recalled (Class I): AttorneyOne Monitors and Keeps Consumers Informed 2Health News:DePuy Synthes Craniomaxillofacial Distraction System Recalled (Class I): AttorneyOne Monitors and Keeps Consumers Informed 3Health News:The Northeast Regional Epilepsy Group (NEREG) Offers First Conference on Psychogenic Non-epileptic Seizures (PNES) on September 20, 2014 in New Jersey 2
... and people without health insurance especially vulnerable, study says ... an estimated 6,200 Americans are hospitalized for heat exposure. ... hospitalized died, according to the latest News and ... and Quality. , Severe heat exposure, which is ...
... a premier research company in San Jose, releases several research projects ... the product's current market scenario, factors influencing the market, growth drivers, ... development activities, and strategic corporate activity of major market participants. ... ...
... breathe clean air inside all workplaces,including restaurants and ... A poll released today,finds that voters from Boone, ... inside all workplaces, including restaurants and bars., ... percent), Northern Kentucky,voters support a law prohibiting smoking ...
... 9 The Congressional Budget,Office (CBO) estimates that ... (H.R. 6331) would decrease enrollment in Medicare,Advantage by ... years. Karen,Ignagni, President and CEO of America,s Health ... than two million seniors across the country stand ...
... N.J., July 9 Zeus Scientific, Inc. today,announced ... test for,methicillin-resistant Staphylococcus aureus (MRSA). The test is ... and nucleic acid,amplification of a target pathogen., ... new MRSA,test will enable healthcare professionals to identify ...
... at the University of Alabama at Birmingham (UAB) have ... Project. The project is a national consortium of cutting-edge ... survival for patients with a kind of malignant brain ... nine-member consortium, UAB will serve as the only research ...
Cached Medicine News:Health News:Heat Exposure a Dangerous Summer Threat 2Health News:Global Industry Analysts' Releases a Series of Medical Market Research Reports 2Health News:Global Industry Analysts' Releases a Series of Medical Market Research Reports 3Health News:Northern Kentucky Voters Support Smokefree Workplaces 2Health News:Northern Kentucky Voters Support Smokefree Workplaces 3Health News:Northern Kentucky Voters Support Smokefree Workplaces 4Health News:UAB joins elite brain cancer research group 2
(Date:8/29/2014)... 2014  United Therapeutics Corporation (NASDAQ: UTHR ... the District of New Jersey ... against Sandoz, Inc. regarding United Therapeutics, Remodulin ® ... that U.S. Patent No. 6,765,117 is both valid and ... its generic product until the expiration of that patent ...
(Date:8/29/2014)... PITTSBURGH , Aug. 29, 2014 /PRNewswire-iReach/ -- ChemImage ... at the Australian and New Zealand Forensic Science ... Forensic Sciences in Adelaide, Australia ... discussion concerning the advancements that hyperspectral imaging can ... Jeffrey Beckstead , Director of Product Development ...
(Date:8/29/2014)... VANCOUVER, British Columbia and MENLO ... -- DelMar Pharmaceuticals, Inc. (OTCQB: DMPI) ("DelMar" ... 2014 fiscal year-end financial statements.  The Company recently changed ... to facilitate an application to list its common stock ... possible. DelMar,s financial statements as filed with ...
Breaking Medicine Technology:District Court Decision Received In Remodulin Patent Case 2ChemImage to Discuss Hyperspectral Imaging for Forensic Investigation at the ANZFSS 22nd International Symposium on the Forensic Sciences 2ChemImage to Discuss Hyperspectral Imaging for Forensic Investigation at the ANZFSS 22nd International Symposium on the Forensic Sciences 3DelMar Pharmaceuticals Fiscal 2014 Year End Results and Summary of Recent Developments 2DelMar Pharmaceuticals Fiscal 2014 Year End Results and Summary of Recent Developments 3DelMar Pharmaceuticals Fiscal 2014 Year End Results and Summary of Recent Developments 4DelMar Pharmaceuticals Fiscal 2014 Year End Results and Summary of Recent Developments 5
... WARSAW, Ind., Oct. 3, 2011 Zimmer Holdings, Inc. (NYSE: ... quarter 2011 sales and earnings conference call will be broadcast ... 8:00 a.m. Eastern Time.  A news release detailing the quarterly ... the morning of the conference call. The ...
... In a presentation at the Congress of Neurological Surgeons ... reported that preliminary results of a pilot clinical trial ... safely and effectively control essential tremor (ET), a common ... Results from the study,s first 10 patients showed ...
Cached Medicine Technology:Zimmer Holdings Announces Live Audio Webcast and Conference Call of Third Quarter 2011 Results 2Focused Ultrasound Shows Promise as a Noninvasive Deep Brain Treatment for Essential Tremor, a Condition That Affects Millions 2Focused Ultrasound Shows Promise as a Noninvasive Deep Brain Treatment for Essential Tremor, a Condition That Affects Millions 3Focused Ultrasound Shows Promise as a Noninvasive Deep Brain Treatment for Essential Tremor, a Condition That Affects Millions 4
Ideal for nucleus manipulation during phacoemulsification. Also used for manipulating and rotating IOLs within the anterior chamber. Round knurled handle...
Short, narrow paddle angled 45 degree inserts through the side port stab incision and is ideal for effective manipulation of the lens during anterior chamber phacoemulsification....
Nucleus divider with 1.25 mm tip and blade offset at a 60 degree angle is ideal for performing the "Phaco Chop" technique. Round knurled handle. Manufactured in titanium....
#2 10 mm hook. Flat serrated handle with polished finish. Overall length: 5.5 inches....
Medicine Products: