Navigation Links
Biochemical markers for non-invasive assessment of primary biliary cirrhosis
Date:2/17/2009

Needle liver biopsy has been used as the "gold standard" for the assessment of liver fibrosis and disease stage of PBC . Due to possible complications of this procedure, for both, the physician and the patient, the decision to proceed with liver biopsy is not trivial one. So, scientists tend to introduce non-invasive methods for assessment of liver diseases stages.

A research article to be published on February 7, 2009 in the World Journal of Gastroenterology addresses this question. In the literature, The research team was led by Tamara Alempijevic found a statistical significant correlation between PBC stage and AST, APRI, ALT/platelet, AST/ALT, ALT/AST and ALT/Chol ratio. The best sensitivity and specificity was shown for AST/ALT, with the area under ROC of 0.660.

Based on these results, they concluded that use of biochemical markers and their ratios in clinical evaluation of PBC patients may reduce, but not eliminate the need for liver biopsy.


'/>"/>

Contact: Lin Tian
wjg@wjgnet.com
86-105-908-0039
World Journal of Gastroenterology
Source:Eurekalert

Page: 1

Related medicine news :

1. Scientists Spot Biochemical Sign of Depression
2. Major missed biochemical pathway emerges as important in virtually all cells
3. Prenatal biochemical screening only detects half of chromosomal abnormalities
4. UCLA researchers identify markers that may predict diabetes in still-healthy people
5. Penn School of Medicine receives $2.3 million to study biomarkers of cigarette smoke exposure
6. Study makes progress in zoning in on biomarkers for better colon cancer treatment
7. Study shows blood markers can help choose best dose for antiangiogenic drugs
8. Biomarkers predict risk for invasive breast cancer years before the tumor develops
9. 2 proteins may be survival markers in some breast cancers
10. JDRF and Lilly partner to fund research to identify beta cell biomarkers
11. Biomarkers for Alzheimers disease can be trusted in clinical trials
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2014)... (PRWEB) July 31, 2014 Atlanta-based Jvion, ... released their top three lessons in predictive population health ... understanding and applying predictive analytics in healthcare. Ritesh Sharma, ... together as an industry to understand the impact of ... of information out there and a good portion of ...
(Date:7/31/2014)... July 31, 2014 The rising population ... factor driving the global geriatric care services market wherein ... supply of these services across the globe. There are ... home care agency to few large companies with national ... is underserved and is also highly fragmented. The developed ...
(Date:7/31/2014)... the winter of 1944, the Nazis blocked food supplies ... famine and devastation. The impact of starvation on expectant ... changes resulting from external rather than genetic influences ... hardship could be inherited. The underlying mechanism, however, remained ... in the journal Cell , Dr. Oded Rechavi, ...
(Date:7/31/2014)... The “Nucleic Acid Isolation and Purification Market by ... Consumables & Instruments, by Application (Plasmid DNA isolation, ... Global Forecasts to 2018” provides a detailed overview ... market trends, and strategies impacting the global nucleic ... estimates and forecasts of the revenue and share ...
(Date:7/31/2014)... 2014 Global Markets , Brain ... overview of the Brain Cancers therapeutic pipeline. , ... development for Brain Cancer, complete with comparative analysis ... mechanism of action (MoA), route of administration (RoA) ... featured news and press releases. It also reviews ...
Breaking Medicine News(10 mins):Health News:Jvion Releases Top Three Lessons in Predictive Population Health Analytics 2Health News:Jvion Releases Top Three Lessons in Predictive Population Health Analytics 3Health News:Geriatric Care Services Market (Home Care, Adult Day Care, and Institutional Care): Global Industry Analysis, Size, Share, Growth, Forecast 2013 - 2019 2Health News:Geriatric Care Services Market (Home Care, Adult Day Care, and Institutional Care): Global Industry Analysis, Size, Share, Growth, Forecast 2013 - 2019 3Health News:Geriatric Care Services Market (Home Care, Adult Day Care, and Institutional Care): Global Industry Analysis, Size, Share, Growth, Forecast 2013 - 2019 4Health News:Geriatric Care Services Market (Home Care, Adult Day Care, and Institutional Care): Global Industry Analysis, Size, Share, Growth, Forecast 2013 - 2019 5Health News:The 'memory' of starvation is in your genes 2Health News:The 'memory' of starvation is in your genes 3Health News:Nucleic Acid Isolation Market Worth $3,106.28 Million by 2018 - New Research Report by MarketsandMarkets 2Health News:Nucleic Acid Isolation Market Worth $3,106.28 Million by 2018 - New Research Report by MarketsandMarkets 3Health News:Nucleic Acid Isolation Market Worth $3,106.28 Million by 2018 - New Research Report by MarketsandMarkets 4Health News:Global Brain Cancer Market Size, Share, Analysis, Trends and Forecasts 2014 2Health News:Global Brain Cancer Market Size, Share, Analysis, Trends and Forecasts 2014 3Health News:Global Brain Cancer Market Size, Share, Analysis, Trends and Forecasts 2014 4
... 26 A hospital is no place to be,left ... it only,takes an instant for a dangerous accident to ... recovery and even increase the pain a patient suffers. ... hospital sitter, a specialized caregiver who provides,round-the-clock companionship and ...
... and device sponsors, CROs, consultants, and enrollment services providers will ... Management for Patient Recruitment Success Forum (April 20 - 21, ... ... PA (Vocus) February 26, 2009 -- Executive-level management from biopharma ...
... PLAINS, N.Y., Feb. 26 ABC,s hit television series ... p.m. (ET) episode on a March of Dimes volunteer ... born prematurely and whose home was later destroyed by a ... home in less than a week,s time during the taping ...
... Becker and Army Pilot Robert Cuyler Honored for Comebacks ... young mom and entrepreneur dedicated to improving the lives ... National Award recipient and Army helicopter pilot Robert (Bob) ... Snow Public Service Award at a ceremony here this ...
... the children of Jade Goody who will be left ... teen pop star, Chantel "Chani" Christie who recently won ... Excellence in Hip-Hop, is set to donate proceeds from ... ill reality television star, Jade Goody. In addition, she ...
... OF MICHIGAN URGES DETROIT EMPLOYERS TO SEE INFLUENZA AS ... in billions of dollars in lost wages every year, ... missed workdays a year, and about 200 million days ... Yet vaccination rates remain alarmingly low, especially among working ...
Cached Medicine News:Health News:Sitters are New Members of the Hospital Team! 2Health News:DIA to host Patient Recruitment and Retention Forum April 20-21, 2009 2Health News:DIA to host Patient Recruitment and Retention Forum April 20-21, 2009 3Health News:ABC's Extreme Makeover: Home Edition Gives Parents of Preemie a New Home 2Health News:Great Comebacks(R) Program Announces 2008 National Award Winner and Inaugural Tony Snow Public Service Award 2Health News:Great Comebacks(R) Program Announces 2008 National Award Winner and Inaugural Tony Snow Public Service Award 3Health News:Great Comebacks(R) Program Announces 2008 National Award Winner and Inaugural Tony Snow Public Service Award 4Health News:Great Comebacks(R) Program Announces 2008 National Award Winner and Inaugural Tony Snow Public Service Award 5Health News:Great Comebacks(R) Program Announces 2008 National Award Winner and Inaugural Tony Snow Public Service Award 6Health News:Chantel 'Chani' Christie Will Donate Proceeds From Her Top-Selling Debut Album 'My Dream' to the Children of Terminally Ill TV Star Jade Goody 2Health News:Influenza Infection Costs Employers Billions Each Year; Working Adults Largest Group Not Immunized Annually 2Health News:Influenza Infection Costs Employers Billions Each Year; Working Adults Largest Group Not Immunized Annually 3Health News:Influenza Infection Costs Employers Billions Each Year; Working Adults Largest Group Not Immunized Annually 4
(Date:7/31/2014)... , July 31, 2014  Today, ... a new extension to its PageCenterX ® ... software is designed to provide downtime reporting capabilities ... outages. LRS is releasing the product for general ... environment, EMR applications experience outages for a variety ...
(Date:7/31/2014)... 2014 Orexigen® Therapeutics, Inc. (Nasdaq: ... quarter 2014, on Thursday, August 7, 2014 before markets ... webcast and conference call at 8:00 a.m. Eastern time ... host the call and webcast to discuss financial results ... accessed by calling (800) 708-4540 (domestic) or (847) 619-6397 ...
(Date:7/31/2014)... SCOTTSDALE, Ariz. , July 31 2014  Northsight ... Bluher has been named Chairman and CEO of ... governance, risk management, legal matters, business development and investment ... in the securities industry.  Before his career on Wall ... Enforcement Division of the U.S, Securities and Exchange Commission ...
Breaking Medicine Technology:LRS Announces Downtime Reporting Solution for Healthcare 2Orexigen Therapeutics to Host Second Quarter 2014 Financial Results Conference Call and Webcast 2Northsight Capital, Inc. Names Wall Street Veteran John Bluher, Former EVP And General Counsel Of Knight Trading Group, Chairman And CEO. 2
... (TSH) is a 32 kDa glycoprotein secreted ... pituitary gland [1]. The structure of human ... pituitary and placental gonadotropins, consisting of an ... these hormones and a unique beta-subunit, which ...
... (T4) is the primary active hormone synthesized ... gland [1]. T4 is synthesized via a ... by the follicular cells, (ii) iodination of ... to formation of 3-monoiodotyrosine and 3,5-diiodotyrosine (MIT ...
... produced primarily by 5-monodeioination of thyroxine (T4) ... T3 production occurs at a rate which ... Release of T3 from the thyroid gland ... compared to 80-100 micrograms/day for T4. In ...
... protein-3 (IGFBP-3) is the main binding protein for ... component of the ~150 kDa ternary complex. This ... or IGF-II and ALS, allowing IGFBP-3, along with ... The molar concentration of IGFBP-3 in normal serum ...
Medicine Products: