Navigation Links
Biochemical markers for non-invasive assessment of primary biliary cirrhosis
Date:2/17/2009

Needle liver biopsy has been used as the "gold standard" for the assessment of liver fibrosis and disease stage of PBC . Due to possible complications of this procedure, for both, the physician and the patient, the decision to proceed with liver biopsy is not trivial one. So, scientists tend to introduce non-invasive methods for assessment of liver diseases stages.

A research article to be published on February 7, 2009 in the World Journal of Gastroenterology addresses this question. In the literature, The research team was led by Tamara Alempijevic found a statistical significant correlation between PBC stage and AST, APRI, ALT/platelet, AST/ALT, ALT/AST and ALT/Chol ratio. The best sensitivity and specificity was shown for AST/ALT, with the area under ROC of 0.660.

Based on these results, they concluded that use of biochemical markers and their ratios in clinical evaluation of PBC patients may reduce, but not eliminate the need for liver biopsy.


'/>"/>

Contact: Lin Tian
wjg@wjgnet.com
86-105-908-0039
World Journal of Gastroenterology
Source:Eurekalert

Page: 1

Related medicine news :

1. Scientists Spot Biochemical Sign of Depression
2. Major missed biochemical pathway emerges as important in virtually all cells
3. Prenatal biochemical screening only detects half of chromosomal abnormalities
4. UCLA researchers identify markers that may predict diabetes in still-healthy people
5. Penn School of Medicine receives $2.3 million to study biomarkers of cigarette smoke exposure
6. Study makes progress in zoning in on biomarkers for better colon cancer treatment
7. Study shows blood markers can help choose best dose for antiangiogenic drugs
8. Biomarkers predict risk for invasive breast cancer years before the tumor develops
9. 2 proteins may be survival markers in some breast cancers
10. JDRF and Lilly partner to fund research to identify beta cell biomarkers
11. Biomarkers for Alzheimers disease can be trusted in clinical trials
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/23/2017)... , ... April 23, 2017 , ... ... managed services announced the achievement of Cisco Select certification and SMB specialization. ... United States. , In earning the Select Certification, Altura fulfilled the ...
(Date:4/22/2017)... Juan Capistrano (PRWEB) , ... April 22, 2017 , ... The San Juan Capistrano ... recently released a parenting report outlining the need for summer camps to provide physical activities ... The Importance of Physical Activity In Summer Camps , With an increase in specialty camps ...
(Date:4/21/2017)... ... April 21, 2017 , ... Chicago plastic surgeon, Dr. Anil R. Shah, ... is a benign bony lump located on the forehead usually attributed to a facial ... sight and pain. Dr. Shah has discovered an approach that is minimally invasive. He ...
(Date:4/21/2017)... ... April 21, 2017 , ... The adage “Show, don’t tell” applies perfectly ... in the company’s esteemed VISION House demonstration project series. Manifesting the concept of right-sized ... resources they need to live affordably and abundantly without unduly taxing the resources of ...
(Date:4/21/2017)... ... 2017 , ... The American Medical Student Association (AMSA) will ... Education, from April 24 to April 28, 2017, dedicated to increasing awareness about ... mission of AWARE is to instill a compassionate, total health approach to treating ...
Breaking Medicine News(10 mins):
(Date:4/18/2017)... BLOOMINGTON, Minn. , April 18, 2017 /PRNewswire/ ... ("Imprimis"), an ophthalmology-focused pharmaceutical company, and Cameron Ehlen ... the signing of a three-year exclusive sales representation ... a dedicated sales team to introduce Imprimis, ophthalmic ... focused in 13 states in the U.S. Midwest. Precision ...
(Date:4/18/2017)... 18, 2017 Research and Markets has ... States Molecular Imaging Equipment and Radiopharmaceuticals Market, Forecast to 2023" ... ... equipment revenues as well as growth in the number of ... value to market participants that design and manufacture molecular imaging ...
(Date:4/18/2017)... 2017 Recursion Pharmaceuticals , an emerging ... learning techniques to discover treatments for rare genetic diseases, ... as vice president of biology. Chong joins the ... Belgium , where as a principal ... high-dimensional biological approaches to the small molecule lead discovery ...
Breaking Medicine Technology: