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Bioabsorbable stents show promise
Date:3/13/2009

and radial strength for a longer time period.

The fact that vasomotion (the ability to undergo vasodilation and vasoconstriction) was restored in response to vasoactive agents in the stented vessel segment was a really good sign. It shows that after two years the physiological function of the stented part of the vessel has been almost completely restored, and that patients will not get any symptoms of angina or limitations in physical activity. In contrast, for first generation drug eluting stents, studies have shown "paradoxical vasoconstriction" in the area of the stent, where the vessel constricts instead of opening during exercise.

This is a proof of principle study that teaches us a lot about the way bioabsorbable stents work and affect remodelling of the stented vessel segment. But with only 30 patients included in the study, numbers are too small to show us if the technology is safe. Furthermore the study was only performed in patients with single de novo coronary lesions, who are considered by far the most straight forward cases. The study doesn't show us if the new stent will work in real world situations of patients with long lesions, calcification or bifurcations."


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Contact: ESC Press Office
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European Society of Cardiology
Source:Eurekalert

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