Navigation Links
BioSTARTM device achieves 90 percent closure rate for atrial septal defect in children
Date:7/15/2010

A novel study by Canadian physicians reported that the BioSTARTM biodegradable implant achieved comparable closure rates to the Amplatzer Septal OccluderTM (ASO) in children with atrial septal defect (ASD). The BioSTAR device displayed successful outcomes, while avoiding issues associated with implants containing substantial amounts of metal. Results of the study, the first to compare the BioSTAR device with the ASO in children, are now available online and in the July print issue of Catheterization and Cardiovascular Interventions, a journal published by Wiley-Blackwell on behalf of The Society for Cardiovascular Angiography and Interventions.

ASD is a congenital heart defect where a hole is present in the wall between the two upper heart chambers. While smaller ASDs may close on their own in early life, larger defects may require surgery to close the opening. If left untreated, ASD may increase the risk of developing atrial fibrillation, heart failure, or stroke later in life. The incidence of atrial septal defects ranges from one-twentieth to one-tenth of all congenital heart lesions.

During the study period of November 1, 2007 through November 30, 2008 there were 54 children who underwent ASD closure with the ASO implant. The ASO group subjects' median data were: age of 7.4, weight of 23.3 kg, defect size of 10 mm, and balloon stretched size of 12.7 mm. The BioSTAR implant was used in 10 patients where a small to moderate defect was anticipated by non-invasive studies. In this group, patients' median data were: age of 11, weight of 39.6 kg, defect size of 10 mm, and balloon stretched size of 11.5 mm.

Study results indicated the acute and 6-month follow up closure rate for the BioSTAR were both 90%, compared with 100% for both time periods with the ASO implants. "Our study provides evidence that the BioSTAR implant achieves comparable closure rates to the ASO device in small- to moderate-ASD," said lead study author Lee Benson, M.D., FSCAI. "Minimal foreign material remains after 6 months with the biodegradable implant, reducing the risks associated with devices containing significant amounts of metal." The study team noted that decreased long-term thrombogenicity, preserved transseptal access, decreased inflammatory response, and reduced potential of arrhythmogenicity and erosion were benefits of using biodegradable implants.

The team reported no serious complications in either group. However, statistically significant differences in the median procedure time (BioSTAR-52 minutes; ASO device-39.5 minutes) and fluoroscopy times (BioSTAR-6.7 minutes; ASO device-6.1 minutes) were observed. "Longer procedure and fluoroscopy times are a drawback of the BioSTAR implant, but should improve with familiarity with the device and deployment system," Dr. Benson concluded.


'/>"/>

Contact: Dawn Peters
healthnews@wiley.com
781-388-8408
Wiley-Blackwell
Source:Eurekalert

Related medicine news :

1. Radiation device allows for targeted breast radiation to control cancer
2. RMSR Certification Gains Medical Device & Equipment Industry Acceptance for Medical Sales Reps
3. Scientists design new delivery device for gene therapy
4. A/C Mist Device Cools Down Air Conditioners, Utility Bills
5. Aspirus Heart & Vascular Institute Surgeon First in State to Implant Heart Device
6. AMP asks FDA to address barriers to device innovation
7. Mobile and Patented: DATA-TO-CAMERA TOGGLE on handheld device replaces old camera and clipboard approach everywhere! Beats IPAD to camera punch too.....
8. My Endpoint Protector Device Control is Now Available for Home Users Free of Charge
9. Jell-O lab-on-a-chip devices to spark interest in science careers
10. Molecular Devices Relaunches with HiveMind Marketing
11. Intrauterine devices reduce repeat abortions
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/8/2016)... ... December 08, 2016 , ... ... distinction by the Undersea and Hyperbaric Medical Society (UHMS), the leading authority in ... and patient safety. Only a few hospitals and facilities have earned this distinction. ...
(Date:12/8/2016)... ... December 08, 2016 , ... ... Therapy Management (MTM), adherence, and other pharmacist-delivered patient care services, has announced the ... and Eric Hoessel to vice president of sales. , Litsinger joined Mirixa ...
(Date:12/8/2016)... ... December 08, 2016 , ... ... for customers and employees that are both engaging and easy to use. Coming ... Technology, the software company revealed today its plans to roll out new AI-powered ...
(Date:12/8/2016)... ... ... California Senate Bill (SB) 863, signed into law in 2012, may have ... according to CompScope™ Medical Benchmarks for California, 17th Edition , a study by ... payments per claim in California decreased 4 percent in 2013 and then 3 percent ...
(Date:12/8/2016)... ... December 08, 2016 , ... The Dianne Michael Insurance Agency, ... Hamilton County, is embarking on a charity drive with the aim of generating ... for orphaned or neglected senior dogs in the Cincinnati region, and LuvFurMutts volunteers ...
Breaking Medicine News(10 mins):
(Date:12/9/2016)... Dec. 9, 2016  Axovant Sciences Ltd. (NYSE: ... company focused on the treatment of dementia, today ... a Phase 2b trial evaluating treatment with intepirdine ... with donepezil plus placebo in people with mild-to-moderate ... of intepirdine to treatment was associated with reduced ...
(Date:12/8/2016)... 8, 2016 KEY FINDINGS ... Patient warming and ... blood during surgeries, lowering the risks of neurological disorders post ... SSIs. The patient warming systems can be segmented into convective ... in turn reduce the stay at hospitals thus, lowering the ...
(Date:12/8/2016)... -- Diplomat Pharmacy, Inc. (NYSE: DPLO) has been recognized by the ... National Standard. To learn more about Diplomat,s career opportunities, ... ... ... WorkplaceDynamics, LLC, a research firm specializing in organizational health and workplace ...
Breaking Medicine Technology: