Navigation Links
BioSTARTM device achieves 90 percent closure rate for atrial septal defect in children
Date:7/15/2010

A novel study by Canadian physicians reported that the BioSTARTM biodegradable implant achieved comparable closure rates to the Amplatzer Septal OccluderTM (ASO) in children with atrial septal defect (ASD). The BioSTAR device displayed successful outcomes, while avoiding issues associated with implants containing substantial amounts of metal. Results of the study, the first to compare the BioSTAR device with the ASO in children, are now available online and in the July print issue of Catheterization and Cardiovascular Interventions, a journal published by Wiley-Blackwell on behalf of The Society for Cardiovascular Angiography and Interventions.

ASD is a congenital heart defect where a hole is present in the wall between the two upper heart chambers. While smaller ASDs may close on their own in early life, larger defects may require surgery to close the opening. If left untreated, ASD may increase the risk of developing atrial fibrillation, heart failure, or stroke later in life. The incidence of atrial septal defects ranges from one-twentieth to one-tenth of all congenital heart lesions.

During the study period of November 1, 2007 through November 30, 2008 there were 54 children who underwent ASD closure with the ASO implant. The ASO group subjects' median data were: age of 7.4, weight of 23.3 kg, defect size of 10 mm, and balloon stretched size of 12.7 mm. The BioSTAR implant was used in 10 patients where a small to moderate defect was anticipated by non-invasive studies. In this group, patients' median data were: age of 11, weight of 39.6 kg, defect size of 10 mm, and balloon stretched size of 11.5 mm.

Study results indicated the acute and 6-month follow up closure rate for the BioSTAR were both 90%, compared with 100% for both time periods with the ASO implants. "Our study provides evidence that the BioSTAR implant achieves comparable closure rates to the ASO device in small- to moderate-ASD," said lead study author Lee Benson, M.D., FSCAI. "Minimal foreign material remains after 6 months with the biodegradable implant, reducing the risks associated with devices containing significant amounts of metal." The study team noted that decreased long-term thrombogenicity, preserved transseptal access, decreased inflammatory response, and reduced potential of arrhythmogenicity and erosion were benefits of using biodegradable implants.

The team reported no serious complications in either group. However, statistically significant differences in the median procedure time (BioSTAR-52 minutes; ASO device-39.5 minutes) and fluoroscopy times (BioSTAR-6.7 minutes; ASO device-6.1 minutes) were observed. "Longer procedure and fluoroscopy times are a drawback of the BioSTAR implant, but should improve with familiarity with the device and deployment system," Dr. Benson concluded.


'/>"/>

Contact: Dawn Peters
healthnews@wiley.com
781-388-8408
Wiley-Blackwell
Source:Eurekalert

Related medicine news :

1. Radiation device allows for targeted breast radiation to control cancer
2. RMSR Certification Gains Medical Device & Equipment Industry Acceptance for Medical Sales Reps
3. Scientists design new delivery device for gene therapy
4. A/C Mist Device Cools Down Air Conditioners, Utility Bills
5. Aspirus Heart & Vascular Institute Surgeon First in State to Implant Heart Device
6. AMP asks FDA to address barriers to device innovation
7. Mobile and Patented: DATA-TO-CAMERA TOGGLE on handheld device replaces old camera and clipboard approach everywhere! Beats IPAD to camera punch too.....
8. My Endpoint Protector Device Control is Now Available for Home Users Free of Charge
9. Jell-O lab-on-a-chip devices to spark interest in science careers
10. Molecular Devices Relaunches with HiveMind Marketing
11. Intrauterine devices reduce repeat abortions
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/24/2017)... ... March 24, 2017 , ... ... (ONS) wanted to create a communications platform that positions them as the go-to ... and ONS reinvented their online publication as an always-on, always-fresh news, views and ...
(Date:3/24/2017)... ... March 24, 2017 , ... The law firm of ... is pleased to announce Westchester resident Lauren C. Enea has joined the firm as ... firm, will concentrate her practice in elder law, Medicaid planning and applications, and Wills, ...
(Date:3/24/2017)... ... March 24, 2017 , ... Empower Brokerage, ... their training and leads programs. , In February, 2017, Empower Brokerage introduced their ... Performance Partners is designed to teach how to maximize their sales efforts, as ...
(Date:3/24/2017)... ... 2017 , ... “End Time GPS”: a dauntless and enlightened study of ... GPS” is the creation of published author, Wesley Gerboth, a World War II veteran, ... space-vehicle projects. Now, at age ninety-one, he shares the Wisdom God bestowed upon him ...
(Date:3/24/2017)... ... March 24, 2017 , ... “The Adventures of Joey, The Dog ... dog who lives his life to the fullest, as God intended. “The Adventures of ... Holmgren, a mother and grandmother pursuing her passion for writing, especially about truth and ...
Breaking Medicine News(10 mins):
(Date:3/24/2017)...   The Accreditation Council for Medical Affairs ... the pharmaceutical industry has appointed Dr. Jane ... formed scientific advisory board. Dr. Chin will be ... ever medical affairs think tank within the pharmaceutical ... ACMA, please visit  www.medicalaffairsspecialist.org .  Connect with ...
(Date:3/24/2017)... FinancialBuzz.com News Commentary  ... According to new data published Arcview ... legal cannabis market is projected to continue to grow at ... the current presidential administration. The report created by Arcview,s data ... growth in this industry are the passage and subsequent implementation ...
(Date:3/24/2017)... -- Research and Markets has announced the addition of the ... their offering. ... pipeline is very strong with a total of 97 drug candidates. Pharma ... Sanofi are involved in the development of the IPF therapeutics. The IPF ... III stage, 15 are in Phase II stage, 12 are in Phase ...
Breaking Medicine Technology: