Navigation Links
BioMarin Provides Grant to NORD to Expand PKU Patient Support Services
Date:10/24/2007

Kuvan, sapropterin dihydrochloride, is the synthetic form of 6R-BH4 (tetrahydrobiopterin), a naturally occurring enzyme cofactor that works in conjunction with phenylalanine hydroxylase (PAH) to metabolize Phe. Clinical data suggest that treatment with Kuvan results in significant reductions in blood Phe levels in BH4-responsive patients. It also may enable some patients to minimize or eliminate highly-restrictive dietary constraints by increasing Phe tolerance levels. BioMarin and Merck Serono estimate that Kuvan could be a potential treatment option for approximately 30 percent to 50 percent of the estimated 50,000 identified PKU patients in the developed world.

Kuvan has received orphan drug designation from both the U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMEA). If approved, it will receive seven years of market exclusivity in the United States and 10 years in the European Union for this indication. Additionally, the FDA has granted Kuvan Fast Track designation, which is designed to facilitate the development of new drugs that are intended to treat serious or life-threatening conditions and that demonstrate the potential to address unmet medical needs.

About BioMarin

BioMarin develops and commercializes innovative biopharmaceuticals for serious diseases and medical conditions. The company's product portfolio comprises two approved products and multiple clinical and preclinical product candidates. Approved products include Naglazyme(R) (galsulfase) for mucopolysaccharidosis VI (MPS VI), a product wholly developed and commercialized by BioMarin, and Aldurazyme(R) (laronidase) for mucopolysaccharidosis I (MPS I), a product which BioMarin developed through a 50/50 joint venture with Genzyme Corporation. Investigational product candidates include Kuvan(TM) (sapropterin dihydrochloride), a Phase 3 product candidate for the treatment of phenylketonuria (PKU), and 6R-BH4 for cardiovascular indications, which is curre
'/>"/>

SOURCE BioMarin Pharmaceutical Inc.
Copyright©2007 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3 4 5

Related medicine news :

1. Protein provides antioxidant protection to Neurons
2. Acupuncture provides relief
3. Micro-camera provides new breast imaging technique
4. Hormone therapy provides no heart benefit
5. MicroRNA provides new insight into birth defects
6. Drug Spironolactone Provides Renal And Cardioprotection In Diabetic Patients
7. Neurobiology Provides Answers To Block Memory-Related Drug Cravings
8. Cholesterol provides immunity against infection by certain parasites
9. John Hopkins CGHH program provides Global Health education
10. London Hospital Provides Specialized Care For Pregnant Women
11. Hope Lodges provides free stay to cancer patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/20/2013)... BroadConnect Telecom, North America’s leading provider ... solution announced the release of its latest ... customers with detailed advice for enhancing the effectiveness ... the latest solution sets, BroadConnect SMEs and highly ... of the most commonly asked customer questions; giving ...
(Date:5/20/2013)... 20, 2013 The Mesothelioma Victims ... US Navy Veterans who are diagnosed with mesothelioma get ... because they, or their family members turned to a ... one of the most skilled, and experienced mesothelioma lawyers ... of mesothelioma in the US never even bother to ...
(Date:5/20/2013)... Healing Heart Urgent Care is pleased ... Briarcliff Road in the Druid Hills neighborhood of Atlanta. ... Fidias E. De León M.D. and a group of ... medical services, occupational health, chiropractic care and massage therapy ... They also offer a full range of physicals that ...
(Date:5/20/2013)... FixturesAndDisplays.com, the leading online retail store supplier, ... clothing display options to clients ranging from boutique owners ... expansive product line includes metal rack and wall displays ... options. Recently the firm has expanded its ... reformulated “green” versions. These display items are both ...
(Date:5/20/2013)... (PRWEB) May 20, 2013 Today is ... Perfect Interview Answers Webinar tomorrow. Job seekers ... Career Confindential’s expert career coach, will show job seekers ... Webinar attendees will also learn the perfect interview answers ... as interview techniques that will get them hired. Job ...
Breaking Medicine News(10 mins):Health News:BroadConnect’s Latest Video Solution Sets Aimed at Providing Technical Insights for Businesses Hoping to Gain Greater Returns from their Investment in Communication and Security Solutions 2Health News:Mesothelioma Victims Center Urges US Navy Veterans Diagnosed With Mesothelioma To Call Them For The Names Of The Nation's Best Mesothelioma Lawyers-Better Compensation 2Health News:Mesothelioma Victims Center Urges US Navy Veterans Diagnosed With Mesothelioma To Call Them For The Names Of The Nation's Best Mesothelioma Lawyers-Better Compensation 3Health News:Healing Heart Urgent Care Opens New Office In Atlanta 2Health News:FixturesAndDisplays.com Offers Line of ‘Green’ Mannequins for Retail Displays 2Health News:FixturesAndDisplays.com Offers Line of ‘Green’ Mannequins for Retail Displays 3Health News:Today Is the Last Day to Register for Tomorrow’s Perfect Interview Answers Webinar From Career Confidential 2
... founder and primary teacher, hits five cities in one ... ... Joshua Rosenthal, founder and primary,teacher of the Institute for Integrative Nutrition, the ... cities,between May 17 and June 14. He will demystify the confusion people,experience ...
... Chronic ... Health Conditions - - Younger Adults Show Steepest Rise in ... the scale. For the first time, a majority of the insured population,is being ... nation., Research released today by Medco Health Solutions, Inc. (NYSE: MHS ...
... Amarin Corporation plc,(NASDAQ: AMRN ) today ... representing one ordinary share) ("ADSs") with several new,institutional ... Company, for up to $60 million funded over ... have entered into definitive agreements for,gross proceeds of ...
... RPS, Inc. today announced,the addition of two new members ... RPS as Vice President of Clinical Operations. Neil H.,Shusterman, ... Drug Safety., "We are pleased that both Dr. ... organization. Both individuals bring significant industry,and drug development experience ...
... Gift & Food Retailer Changes to ,Green, Packaging, ... & baked goods retailer, has announced that it will ... gift bag that is completely,reusable, functional, and eco-friendly. This ... environment and become "greener"., Sherry Comes, president of ...
... doctors has fine-tuned the dosage and timing for administering ... caused by bleeding within the brain. The treatment, as ... Nice, France, has been shown to dramatically decrease death ... of stroke. , "We,ve gone from what,s usually an ...
Cached Medicine News:Health News:Institute for Integrative Nutrition Begins Road Tour 2Health News:Chronic Medication Nation: Research Finds Chronic Health Problems Now Afflict More Than Half of All Americans 2Health News:Chronic Medication Nation: Research Finds Chronic Health Problems Now Afflict More Than Half of All Americans 3Health News:Chronic Medication Nation: Research Finds Chronic Health Problems Now Afflict More Than Half of All Americans 4Health News:Amarin Announces Private Placement for up to $60 Million 2Health News:Amarin Announces Private Placement for up to $60 Million 3Health News:Amarin Announces Private Placement for up to $60 Million 4Health News:Amarin Announces Private Placement for up to $60 Million 5Health News:RPS Enhances Clinical Expertise and Leadership with Two Additions to Senior Management Team 2Health News:CoffeeCakes.com Has Recycling 'In the Bag' 2Health News:Researchers fine-tune clot-busting treatment for bleeding in brain 2
(Date:5/17/2013)... today announced that it will report its 2013 first quarter earnings on ... Ed Borkowski , CFO, will host an analyst and ... To participate in the conference call within the U.S. and ... conference call outside the U.S. and Canada , dial ... Participants should dial in 10 minutes prior to the start of the ...
(Date:5/17/2013)... , May 17, 2013  Boehringer Ingelheim will ... disease at the American Thoracic Society International Conference ... , May 17 – 22. Data ... for the treatment of chronic obstructive pulmonary disease ... well as investigational compounds for asthma, idiopathic pulmonary ...
(Date:5/17/2013)... May 17, 2013 Oramed Pharmaceuticals ... oral drug delivery systems, announced today that the United ... Company,s Investigational New Drug application(IND) for ORMD-0801, its oral ... have the FDA clearance to proceed," stated ... trial is a major milestone for Oramed and we ...
Breaking Medicine Technology:Boehringer Ingelheim to Present 17 Abstracts at the Annual American Thoracic Society International Conference 2Boehringer Ingelheim to Present 17 Abstracts at the Annual American Thoracic Society International Conference 3Boehringer Ingelheim to Present 17 Abstracts at the Annual American Thoracic Society International Conference 4Boehringer Ingelheim to Present 17 Abstracts at the Annual American Thoracic Society International Conference 5Boehringer Ingelheim to Present 17 Abstracts at the Annual American Thoracic Society International Conference 6Boehringer Ingelheim to Present 17 Abstracts at the Annual American Thoracic Society International Conference 7Boehringer Ingelheim to Present 17 Abstracts at the Annual American Thoracic Society International Conference 8Oramed Receives FDA Clearance to Initiate Oral Insulin Trials in the U.S. 2Oramed Receives FDA Clearance to Initiate Oral Insulin Trials in the U.S. 3
The Ultra HDL (UHDL) assay is used for the quantitation of high density lipoprotein (HDL) cholesterol in human serum or plasma....
Shandon Paraffin Block Cartons...
... A histological embedment block ... This file system incorporates ... embedment block protection, simplified ... error and facilitation of ...
The Modular Storage Drawers provide permanent storage and identification of up to 165 embedding rings or 250 cassettes per drawer....
Medicine Products: