Navigation Links
Bio-imaging mass spectrometry techniques reveal molecular details about complex systems
Date:9/25/2008

Understanding biology at the systems level is difficult, especially when studying complex specimens like tissue slices or communities of organisms in a biofilm. Scientists must be able to identify, quantify and locate the molecules present in the samples.

At Georgia Tech, researchers from the Colleges of Sciences and Engineering have joined forces to create the Center for Bio-Imaging Mass Spectrometry (BIMS), which aims to tackle these types of challenges.

"We organized this center in 2007 when we saw the enormous potential of mass spectrometry imaging tools and realized that we had a unique ensemble of people at Georgia Tech that would enable us to excel in this field," said Al Merrill, a professor in the School of Biology and the Smithgall Chair in Molecular Cell Biology.

Mass spectrometry imaging is a powerful analytical technique with the potential to unravel the molecular complexities of biological systems. It allows researchers to visualize the spatial arrangement and relative abundance of specific molecules from simple metabolites to peptides and proteins in biological samples.

The technique also takes advantage of the ability of biological molecules to be converted into ions that can then be separated and analyzed by a mass spectrometer. When data are collected from different regions of a sample, the distribution of molecules can be used to create multidimensional images of that sample.

Today, a popular method for studying biological samples is matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS). In this technique, sample preparation plays a very important role in image quality because it requires that a matrix compound be uniformly deposited over the surface of a histological tissue slice mounted on a special plate.

In the April 15 issue of the journal Analytical Chemistry, a research team including Merrill, Cameron Sullards, director of Georgia Tech's Bioanalyt
'/>"/>

Contact: Abby Vogel
avogel@gatech.edu
404-385-3364
Georgia Institute of Technology Research News
Source:Eurekalert  

Page: 1 2 3 4

Related medicine news :

1. Waters SYNAPT HDMS and Xevo TQ MS Recognized for Mass Spectrometry Innovation by Industry Experts
2. Bruker Daltonics Showcasing Novel Proteomics Solutions Based on Mass Spectrometry at the 7th HUPO World Congress 2008
3. Vertos Medical Inc. Presents Clinical Data of its MILD™ Procedure at the 5th Annual Innovative Techniques in Spine Surgery Conference in Los Cabos, Mexico
4. Philips Web Site Offers Seniors and Caregivers Tips and Techniques for Preventing Falls
5. Can pathological techniques help identify primary colorectal signet ring cell carcinoma?
6. New genetic techniques to combat lung cancer
7. Researchers sharpen search for new marine medicines with novel techniques
8. New techniques improve imaging quality, not diagnosis of Barretts esophagus
9. Biopsy techniques have made PSA test less predictive
10. New Technology and Improved Techniques Arm Dermatologists With Tools to Minimize Facial Scars From Skin Cancer Surgery
11. Improved diagnosis of cutaneous leishmaniasis thanks to new techniques
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Bio-imaging mass spectrometry techniques reveal molecular details about complex systems
(Date:4/17/2014)... published in the April issue of Immunity , ... for Medical Research, says it,s time to take a ... treating sepsis, which kills millions worldwide every year, ... molecules released into the bloodstream to fight an injury ... necessary for maintaining good health without inflammation, wounds ...
(Date:4/17/2014)... Doctors who treat patients with a severe and ... an agonizing treatment decision. , The drug sirolimus ... relieve shortness of breath. But some patients eventually ... potentially fatal complications following transplantation. , "It,s a ... director of Loyola University Medical Center,s LAM Clinic ...
(Date:4/17/2014)... April 17, 2014 By discovering a new mechanism ... a stroke, researchers at UC Irvine and the Salk ... may limit or prevent stroke-induced brain damage. , A ... cause of death and primary reason for disability in ... a stroke and lets blood-borne material into the brain, ...
(Date:4/17/2014)... time online has the potential to ward off depression ... to research published online in The Journals ... . In the article " Internet Use and ... A Longitudinal Analysis ," the authors report that Internet ... 33 percent among their study sample. , Late-life ...
(Date:4/17/2014)... April 17, 2014 Meaningful long-term survival is ... of the abdomen when treated with cytoreductive surgery ... a first-of-its-size analysis by physicians at Wake Forest ... the largest reported, single-center experience with cytoreductive surgery ... M.D., and analysis of 20 years, worth of ...
Breaking Medicine News(10 mins):Health News:Feinstein Institute researcher publishes new perspective on sepsis 2Health News:Patients with rare lung disease face agonizing treatment dilemma 2Health News:Patients with rare lung disease face agonizing treatment dilemma 3Health News:Study IDs new cause of brain bleeding immediately after stroke 2Health News:Internet use may cut retirees' depression 2Health News:20 years of data shows treatment technique improvement for advanced abdominal cancer 2
... CHERRY HILL, N.J., Sept. 11 Nuvilex, Inc. (OTC ... its joint venture partner, has informed the company that ... its homeopathic remedy for helping to prevent and treat ... The Reme-Flu(TM) formula consists of a two-part protocol. ...
... Bupa,s Latin America and Caribbean,operation -- a division ... the launch of the international Ecuador Challenge, which will,take ... families survive on,average on just $4 a day. Some ... Ecuador until November 29 to build essential health and ...
... , MISSISSAUGA, Ontario, Sept. 11 JAG ... agreement with The Investor Relations Group, Inc. ("IRG"), pursuant to which ... the Company in accordance with the terms of the agreement. As ... to IRG. , , "We are very excited ...
... , , YARDLEY, Pa., Sept. 11 ... soft tissue and skeletal repair of the extremities, announced today that ... Chairman of the Board, effective immediately. , , ... as it moves from product development to commercialization," said Zev Scherl, ...
... , IRVING, Texas, Sept. 11 ... 643 on its third annual Inc. 5000, an exclusive ranking ... most comprehensive look at the most important segment of the ... rental car service Zipcar, and beverage maker Honest Tea are ...
... - HTDS www.htdsmedical.com The company is pleased ... Hope www.mellowhope.com has successfully completed and delivered ... Bangladesh. , In developing countries, over 11 million children ... nearly three quarters of these deaths result from infectious ...
Cached Medicine News:Health News:Nuvilex, Inc. Announces Reme-Flu(TM) as Trade Name for All-Natural Flu Remedy Formula 2Health News:Nuvilex, Inc. Announces Reme-Flu(TM) as Trade Name for All-Natural Flu Remedy Formula 3Health News:Bupa Launches its 2009 International Charity Challenge to Help a Rural Community in Ecuador 2Health News:JAG Media Holdings, Inc. Announces Agreement with The Investor Relations Group, Inc. 2Health News:John C. Moran Named CEO at Core Essence Orthopaedics 2Health News:SoftLight Development, Inc. Ranks No. 643 on the 2009 Inc. 5000 with Three-Year Sales Growth of 429.7% 2Health News:SoftLight Development, Inc. Ranks No. 643 on the 2009 Inc. 5000 with Three-Year Sales Growth of 429.7% 3Health News:SoftLight Development, Inc. Ranks No. 643 on the 2009 Inc. 5000 with Three-Year Sales Growth of 429.7% 4Health News:SoftLight Development, Inc. Ranks No. 643 on the 2009 Inc. 5000 with Three-Year Sales Growth of 429.7% 5Health News:SoftLight Development, Inc. Ranks No. 643 on the 2009 Inc. 5000 with Three-Year Sales Growth of 429.7% 6Health News:SoftLight Development, Inc. Ranks No. 643 on the 2009 Inc. 5000 with Three-Year Sales Growth of 429.7% 7Health News:Hard To Treat Diseases (HTDS) MEVAC-A Completes Tender For Bangladesh 2Health News:Hard To Treat Diseases (HTDS) MEVAC-A Completes Tender For Bangladesh 3
(Date:1/15/2014)... NEW YORK , Jan. 15, ... new market research report is available ... Global Markets and Technologies for ... on Routes of Administration ...
(Date:1/15/2014)...  A novel wearable injector slightly larger than an Oreo cookie ... self-inject prescription drugs in the large doses required to treat ... deficiencies, and genetic disorders.  An emerging biologic ... according to analysts.   Many of these drugs will require a ...
(Date:1/14/2014)... 2014  Luminex Corporation (Nasdaq: LMNX ) today announced ... of 2013 on Monday, February 3, 2014. A press release ... of trading. (Logo: http://photos.prnewswire.com/prnh/20100104/LUMINEXLOGO ) ... operating highlights and financial results for the fourth quarter and ...
Breaking Medicine Technology:Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 2Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 3Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 4Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 5Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 6Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 7Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 8Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 9Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 10Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 11Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 12Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 13Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 14Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 15Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 16Enable Injections Presents A New Class of Injectors for Drug Delivery at PEPTalk, Drug Delivery Partnership Meetings 2Luminex Corporation Fourth Quarter Earnings Release Scheduled for February 3, 2014 2Luminex Corporation Fourth Quarter Earnings Release Scheduled for February 3, 2014 3
... use in settings where a more secure band is ... but difficult to remove wristband is appropriate. The design ... time. One band to be placed on the wrist ... the first need to be replaced. This is particularly ...
IDENTI-MATCH II is a combination of the IDENTI-MATCH Blood Recipient Identification System and an admitting band. It has been designed for those facilities using label-based patient ID systems....
Zebras H 2824-Z Healthcare Starter Kit includes everything you need to start printing wristbands today: the H 2824-Z direct thermal printer, a pre-installed Media Adapter Guide, and a roll of adult-s...
... VerdaSees Navigaton™ software facilitates real time ... two modules: the first module is ... reader devices and the database where ... second module is the user interface, ...
Medicine Products: