Navigation Links
Binge drinking increases risk of Type 2 diabetes by causing insulin resistance
Date:1/30/2013

Binge drinking causes insulin resistance, which increases the risk of Type 2 diabetes, according to the results of an animal study led by researchers at the Diabetes Obesity and Metabolism Institute at the Icahn School of Medicine at Mount Sinai. The authors further discovered that alcohol disrupts insulin-receptor signaling by causing inflammation in the hypothalamus area of the brain.

The results are published in the January 30 issue of the journal Science Translational Medicine.

"Insulin resistance has emerged as a key metabolic defect leading to Type 2 diabetes and coronary artery disease (CAD)," said Christoph Buettner, MD, PhD, senior author of the study and Associate Professor of Medicine (Endocrinology, Diabetes and Bone Disease). "Someone who regularly binge drinks even once a week, over many years, may remain in an insulin resistant state for an extended period of time, potentially years," said Dr. Buettner.

In this study, researchers treated rats with alcohol for three consecutive days to simulate human binge drinking. A control group received the same amount of calories. Once alcohol was no longer detectable in blood, glucose metabolism was studied through either glucose-tolerance tests or through controlled-insulin infusions. The rats treated with alcohol were found to have higher concentrations of plasma insulin than the control group, suggesting that insulin resistance may have been the cause of the impaired glucose tolerance.

High plasma insulin levels are a major component of the metabolic syndrome, a group of risk factors that occur together and increase the risk for Type 2 diabetes, coronary artery disease, and stroke.

"Previously it was unclear whether binge drinking was associated with an increased risk for diabetes, since a person who binge drinks may also tend to binge eat, or at least eat too much. Our data show for the first time that binge drinking induces insulin resistance di
'/>"/>

Contact: Jeanne Bernard
Jeanne.Bernard@mountsinai.org
212-241-9200
The Mount Sinai Hospital / Mount Sinai School of Medicine
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Binge Drinking Common Among U.S. Women, Girls: CDC
2. Strange Food Pairings May Signal Binge Eating: Study
3. Young Binge Eaters Prone to Illicit Drug Use: Study
4. College Students Who Binge Drink Say Theyre Happier
5. Binge drinking college students are happier than their non-binge drinking peers
6. Binge drinking increases the risk of cognitive decline in older adults
7. Rats, like humans, return to drinking once punishment is removed
8. Doctors Often Miss Signs of Problem Drinking in Patients, Study Finds
9. Protective communities may reduce risk of drinking in teens
10. Heavy Drinking, Pot Use Tied to Teen Brain Changes
11. AddictionFreeCanada.com, At a Recent Press Briefing, Offered Solutions to Dangers Caused by Smoking, Drinking and Gambling.
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/21/2014)... Discount-Dress.com, a company that specializes in fashion garments ... implement a new shopping cart software on its website. ... Furthermore, the company has unveiled a new collection of ... items come in fashionable designs; all of them are ... off. "We are happy to release the new beach ...
(Date:9/21/2014)... (PRWEB) September 21, 2014 ... Fenofibrate (CAS 49562-28-9) Industry, 2009-2019 is a ... and Chinese Fenofibrate (CAS 49562-28-9) industry. The ... Fenofibrate (CAS 49562-28-9) including its classification, application ... and China’s top manufacturers of Fenofibrate (CAS ...
(Date:9/21/2014)... Rio, Colorado (PRWEB) September 21, 2014 ... Colorado, ten teams of disabled and able-bodied athletes rafted ... and completed a ropes course in pursuit of outdoor ... from national non-profit World T.E.A.M. Sports, disabilities proved ... athletes who successfully completed the three stage event. , ...
(Date:9/21/2014)... An experienced review website in the global market, Top10BestSEOHosting.com, ... announced that FatCow ( http://www.top10bestseohosting.com/go/FatCow.com/ ), GoDaddy and Bluehost ... has been a boom in websites in recent years, ... in the number of web hosting companies that offer ... VPS (Virtual Private Server) is the method of partitioning ...
(Date:9/21/2014)... Recently, BambooIndustry.com, an experienced producer of natural bamboo ... panels ( http://www.bambooindustry.com/products/bamboo-panel/ ). The company’s excellent panels are ... available at discounted prices now, from 10 to 30 ... panels are available in many specifications; they are ... them is finely manufactured by qualified workers. They are ...
Breaking Medicine News(10 mins):Health News:Discount-Dress.com Implements A New Shopping Cart Software And Provides New Beach Wedding Dresses 2Health News:Fenofibrate Industry Global and Chinese Analysis for 2014-2019 Now Available at LifeScienceIndustryResearch.com 2Health News:Fenofibrate Industry Global and Chinese Analysis for 2014-2019 Now Available at LifeScienceIndustryResearch.com 3Health News:Fenofibrate Industry Global and Chinese Analysis for 2014-2019 Now Available at LifeScienceIndustryResearch.com 4Health News:Disabled Athletes Excel at World T.E.A.M. Sports’ Adventure Team Challenge 2Health News:Disabled Athletes Excel at World T.E.A.M. Sports’ Adventure Team Challenge 3Health News:Top10BestSEOHosting.com: FatCow, GoDaddy And Bluehost Are The Best VPS Hosting Suppliers 2Health News:Discounted Bamboo Panels For Sale At BambooIndustry.com 2
... News) -- Many seniors may be at increased risk for ... treat thyroid problems, a new study says. The findings ... elderly patients with thyroid problems and that regular dose monitoring ... said. Reporting in the online April 28 edition of ...
... THURSDAY, April 28 (HealthDay News) -- Rising rates of ... cause for concern because excess weight is associated with ... In people with arthritis, obesity is associated with ... total joint replacement and poor outcomes after joint replacement. ...
... THURSDAY, April 28 (HealthDay News) -- Memory in monkeys and ... says. Experiments with rhesus monkeys showed that, like people, ... ability to identify something when you see it. Recall is ... study appears online April 28 in the journal Current ...
... News) -- Your social status affects how your brain ... the new study, brain activity in volunteers was measured ... increased brain activity when shown information about others at ... had greater response to others like them, the investigators ...
... which combines interval training and healthy eating practices seems ... according to the results of a new study from ... physical activity (PIC Centre). Results of the study were ... in Montreal. Within the framework of this study, ...
... oncologist practiced were two factors that strongly influenced the choice ... to an article published April 29 online in the ... IMRT and the cost of radiation therapy increased sharply over ... delivery technique that modulates the radiation beams to conform to ...
Cached Medicine News:Health News:Thyroid Drugs May Raise Fracture Risk in Elderly 2Health News:Rising Obesity Rates Add to Arthritis Woes in U.S. 2Health News:Shared Social Status Boosts Brain Activity, Research Shows 2Health News:Obesity: Conclusive results for the Montreal Heart Institute's EPIC Centre Kilo-Actif program 2Health News:Use of costly breast cancer therapy strongly influenced by reimbursement policy 2
(Date:9/19/2014)... "Copay coupons," a drug manufacturer ... drugs among patients with prescription drug coverage, may now be ... report  from the Department of Health and ... anti-kickback laws prohibit suppliers from offering side-payments to ... the federal government. The report ...
(Date:9/19/2014)... VIEW, Calif. , Sept. 19, 2014 Today, ... in capital from Xiaomi Ventures, Ltd. for its first ... used to continue expanding iHealth,s global reach, accelerate growth ... resources.  As part of the investment, Xiaomi Ventures will ... the areas of cloud infrastructure and ecommerce. ...
(Date:9/19/2014)... LUBBOCK, Texas , Sept. 19, 2014 Kiromic, ... today the addition of Kent Hance , the former ... vice chairman. Hance retired as chancellor in July 2014, after ... pleased to announce that Kent Hance , the most ... joined the Kiromic team not only as an investor, but ...
Breaking Medicine Technology:PCMA: New OIG Report Cites Drug Manufacturer "Copay Coupon" Use in Medicare Part D 2iHealth Raises $25 Million to Fuel Growth and Global Market Share 2Former Texas Tech Chancellor Named New Vice Chairman of the Board of Kiromic, LLC 2
... Calif., May 17, 2012   Accuray Incorporated (Nasdaq: ... announced today the appointment of Richard Pettingill, LFACHE as ... May 11, 2012.   Richard Pettingill,s career ... leadership positions in a variety of prominent organizations. Most ...
... 2012 Simbionix USA Corporation, the ... education products, is proud to announce the release ... GI Mentor™ Express simulator and the ...      (Logo: http://photos.prnewswire.com/prnh/20120502/529202-a) ...
Cached Medicine Technology:Accuray Appoints Richard Pettingill, LFACHE to Board of Directors 2Accuray Appoints Richard Pettingill, LFACHE to Board of Directors 3Simbionix Releases Two New Platforms at the Upcoming DDW and AUA Events 2
... PYREX volumetric pipets are calibrated ... accordance with ASTM E-542, and ... individually serialized and supplied with ... Capacity, traceable to NIST standards. ...
... Subcuticular Skin Stapler is designed to combine ... the rapid closure times associated with metal ... metal staple removal post-operatively., ,The patented INSORB|20 ... patient use device that deploys up to ...
1000L...
... precision, ergonomics, and value!, Comfortable ... soft non-slip, contoured handle , Finer ... plunger spring action , Completely autoclavable ... the need for recalibration , Easy-to-read ...
Medicine Products: