Navigation Links
Biannual Antibiotics May Cut Major Cause of Blindness in Africa
Date:2/19/2008

Ocular strain of chlamydia responds well to expanded treatment, report says

TUESDAY, Feb. 19 (HealthDay News) -- Increasing the administration of antibiotics from annually to twice a year in rural African villages could help reduce serious eye infections that can lead to blindness, a new study suggests.

An ocular strain of the sexual transmitted disease chlamydia causes the contagious eye disease trachoma, the leading infectious cause of blindness worldwide. Although it has been eliminated from Western Europe and the United States, it is still common in poor, arid areas such as rural sub-Saharan Africa.

The study, published in the Feb. 20 issue of the Journal of the American Medical Association, showed that giving azithromycin to all residents in eight Ethiopian villages twice a year for two years reduced infection in preschool children 35-fold, from 31.6 percent to 0.9 percent. In eight other villages where only annual doses of the antibiotic were given, researchers found the infection rate in preschool children dropped only sixfold, from 42.6 percent to 6.8 percent at the end of two years.

The prevalence of infection 24 months after the first dose of antibiotics was significantly lower in children in the biannually treated villages (0.9 percent) than in the annually treated villages (6.8 percent). At 24 months, no infection could be identified in preschool children in six of eight of the residents receiving biannual treatment but only in one of eight of the residents receiving annual treatments.

The World Health Organization has launched a program to control trachoma, relying in large part on annual repeated mass azithromycin administrations. Elimination of ocular chlamydia has become a particularly important goal because of a growing concern that infection may return into communities that have lost some of their immunity to chlamydia after antibiotics are discontinued.

Mathematical models have suggested that elimination is possible but may require relatively frequent treatments in regions with high incidence, according to background information in the article.

Biannual coverage of a large portion of the community may be necessary to eliminate infection from a severely affected community or at least to do so in a timely manner. Although programs may be reluctant to devote their scarce resources to more frequent treatment, this may be more cost-effective in the long term. Local elimination of the ocular strains of chlamydia from villages is a feasible goal but may require biannual distributions in hyperendemic areas. The results of this study confirm models that suggest treatments will need to be given for more than the two years to predictably achieve elimination in more than 95 percent of villages. Whether elimination from a larger area is possible will depend on the frequency of community-to-community transmission, the authors concluded.

More information

The U.S. Centers for Disease Control and Prevention has more about chlamydia.



-- Kevin McKeever



SOURCE: Journal of the American Medical Association, news release, Feb. 19, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Antibiotics Do Little for Inner Ear Infections
2. DNA with a twist: New company to search for cancer drugs and antibiotics
3. Advanced Life Sciences to Participate in Antibiotics Expert Panel at the 10th Annual BIO CEO & Investor Conference
4. Antibiotics May Not Help Mens Chronic Pelvic Pain: Harvard Doctors Discuss Alternatives
5. Ear infection superbug discovered to be resistant to all pediatric antibiotics
6. Antibiotics Not Always Best Bet for Battling Childhood Ear Infections
7. Major study links insurance status to advanced stage in multiple cancers
8. Consumer Group Finds Use of Outdated Data and Other Major Flaws in Economists Defense of Mandatory Purchase of Private Health Insurance
9. Ingen Technologies Brings Oxyview(R) to Asia Through Major Medical Distributor
10. Good Neighbor Pharmacy(R) Makes Major Gift for Endowed Chair in Community Pharmacy at University of the Pacific
11. Gentiva(R) Health Services Agrees to Acquire Major Home Health Provider in CON State of Mississippi
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Biannual Antibiotics May Cut Major Cause of Blindness in Africa
(Date:4/28/2016)... Viejo, CA (PRWEB) , ... April 28, 2016 , ... ... use within Final Cut Pro X . With ProText Layouts, video editors ... tweak animations to match the length and scale of texts. Creating text-based videos ...
(Date:4/28/2016)... ... , ... Head Over Heels Athletic Arts’ gymnast, Brooklyn Varize, has qualified to ... at the University of Montana on April 28-May 1. Varize will compete on Saturday ... order to qualify, Varize needed to place top seven all-around in her respective age ...
(Date:4/28/2016)... ... April 28, 2016 , ... The ... successful events, attracting medical professionals from around the globe who attended a week’s ... Opening Ceremonies Sunday, April 17 included the introduction of the 2016 ARRS Distinguished ...
(Date:4/28/2016)... ... April 28, 2016 , ... Greener Hydroponics is now offering a ... frequently used by professional organic farmers and nurseries according to Sales Manager Joe Steele ... fabric pots. Our goal is to offer wholesale level pricing and ultra-fast shipping for ...
(Date:4/28/2016)... ... April 28, 2016 , ... Horizon ... collaborating with doctors and hospitals to make transformative changes in how health care ... therapy minds this week in discussing breakthroughs in cellular medicine to treat disease. ...
Breaking Medicine News(10 mins):
(Date:4/28/2016)... , April 28, 2016 Oramed ... a clinical-stage pharmaceutical company focused on the development of oral ... in the upcoming PIONEERS 2016 conference, presented by Joseph ... 2016 in New York . Nadav ... at the conference. Presentation Details:   ...
(Date:4/28/2016)... Florida , April 28, 2016 ... the development of innovative peptide and gene-based immunotherapeutics and vaccines ... it will be presenting at the 3rd Annual Growth ... - 5 th , 2016 at Caesars Palace in Las Vegas, ... 8.00 am on Wednesday, May 4 th by Dr. ...
(Date:4/27/2016)... , Schweiz, April 27, 2016 ... Sachs CEO Forums in Zürich gab Strekin ... führenden Wirkstoffkandidaten STR001 zur Erhaltung des Resthörvermögens ... wurde, bekannt. Für die umfassende Phase-II-Doppelblindstudie mit ... Frankreich angeworben. STR001 wird während der Operation ...
Breaking Medicine Technology: