Navigation Links
Better animal-free test for chemicals that can cause contact dermatitis
Date:5/26/2010

Scientists are reporting development of a fast, simple, inexpensive method for determining whether chemicals in consumer products and workplaces may cause skin allergies in people -- a method that does not involve use of animals. Their study appears in ACS' Chemical Research in Toxicology, a monthly journal.

Itai Chipinda and his colleagues note the existence of public sentiment against the use of animals to determine whether ingredients in consumer soaps, shampoos and other consumer products, and workplace chemicals, may cause skin sensitization and contact dermatitis. Chemicals cause dermatitis by bonding to proteins in the skin, and then aggravating the immune system so that redness, irritation, itching, and other symptoms occur. Existing chemical tests use substances like glutathione that mimic skin proteins and bond to allergy-causing ingredients. None, however, are suitable for use in detecting the critical early stages of skin sensitization, the scientists say.

Instead of glutathione, Chipinda and his team developed a test with nitrobenzenethiol as the skin protein surrogate. When used on 20 different chemicals known to cause skin irritation, the test produced positive results. It produced negative results when used to test substances that usually do not produce skin sensitization. "This simple, rapid and inexpensive absorbance-based method has great potential for use as a preliminary screening tool for skin allergens," the report states.


'/>"/>

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society
Source:Eurekalert  

Page: 1

Related medicine news :

1. MIT researchers develop better way to detect food allergies
2. More Steps a Day Lead to Better Health
3. Younger Is Better When Getting Cochlear Implants
4. Good News About Dog Bites and How to Make it Better
5. For Preemies, Better Use of Oxygen Improves Survival
6. Children with epilepsy say their quality of life is better than their parents think
7. New hope for better treatment for a rising cancer
8. Estes Audiology and SERTOMA Club Windcrest Celebrate Better Hearing and Speech Month with Hearing Aid Roundup
9. Estes Audiology and SERTOMA Club Windcrest Celebrate Better Hearing and Speech Month with Hearing Aid Roundup
10. Better Hearing Institute Joins HHS' Office on Women's Health in Promoting National Women's Health Week and Hearing Health
11. Baby swimmers have better balance
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Better animal-free test for chemicals that can cause contact dermatitis
(Date:4/14/2014)... orphaned by HIV/AIDS in South Africa may provide insight ... behavior issues in other areas of the world, which ... that could lead to successful interventions. , A ... United Nations mentions that due to the HIV/AIDS pandemic, ... African, children are at an increased risk for mental ...
(Date:4/14/2014)... A new study shows that moderate to severe ... risk of stroke, cancer and death. , Results of ... to severe obstructive sleep apnea were four times more ... times more likely to have a stroke (HR = ... (HR = 3.4), and 2.5 times more likely to ...
(Date:4/14/2014)... Dallas study involving serious youth offenders, the answer to one ... seven years: "How long do you think you,ll live?", According ... offending over time., Author Dr. Alex Piquero said the study ... of them offend at very high rates and commit more ... much later in life offend much less., "In a lot ...
(Date:4/14/2014)... with symptoms increasing dramatically during some of the most important ... has found. , Depressive symptoms increased on average by 68 ... young men, who were around 25 years old when they ... their children. The results of the study were published April ... is the first to identify when young fathers are at ...
(Date:4/14/2014)... Lower weight babies and babies who aren,t breastfed ... risk of developing chronic inflammation and related health ... study. , "There were good reasons to hypothesize ... inflammation in adulthood," says Thomas McDade (Northwestern University), ... in the Child & Brain Development program. "It ...
Breaking Medicine News(10 mins):Health News:Researchers identify children with emotional behavior difficulties 2Health News:Researchers identify children with emotional behavior difficulties 3Health News:Study links severe sleep apnea to increased risk of stroke, cancer and death 2Health News:UT Dallas study: Youth who fail to envision future commit more crimes 2Health News:Young dads at high risk of depression, too 2Health News:Low birth weight, less breastfeeding create later health risks 2
... Morning Show On 101.9fm THE MIX/WTMX ... Will Be Event Host and Emcee, GURNEE, Ill., Oct. 2 ... one local boy, Jake Robert Widman, of Gurnee, won,t be,blowing out the ... of pediatric cancer called neuroblastoma on May 27, 2005, when he was,just ...
... and treatment of low-back pain has prompted the American ... (ACP) to issue a new treatment guideline. The guideline ... conducted by investigators at the Oregon Evidence-Based Practice Center ... recommendations issued by a panel of experts convened by ...
... to sudden cardiac death , TUESDAY, Oct. 2 ... perindopril, along with a beta blocker, may help ... Marfan syndrome, research shows. , Marfan syndrome, which ... excessive bone elongation and joint flexibility, and eye ...
... Calif., Oct. 2 Angel Flight West (AFW),awarded The ... at,AFW,s 24th Anniversary Awards on Saturday, September 29. Dr. ... year. As an AFW,pilot, he flies people in need ... and from medical facilities. Dr. Irish, like,all AFW volunteer ...
... gamma imaging for both ... NEWPORT NEWS, Va., Oct. 2 Recently published ... Gamma Imaging,(BSGI) may be more specific than MRI ... compiled by Dr. Rachel Brem and,colleagues at The ...
... 2 Aflac today announced,that Jeffrey M. Herbert ... officer of the company,s U.S. insurance operation. Herbert ... for his departure from the,company. (Logo: ... Aflac president and chief,operating officer for Aflac U.S., ...
Cached Medicine News:Health News:Super Jake Foundation Hosts 3rd Annual 'Heroes Bash' on Nov. 3 to Benefit Pediatric Cancer Research 2Health News:Super Jake Foundation Hosts 3rd Annual 'Heroes Bash' on Nov. 3 to Benefit Pediatric Cancer Research 3Health News:New clinical guideline for low-back pain 2Health News:New clinical guideline for low-back pain 3Health News:Drug Combo Helps Fight Marfan Syndrome 2Health News:Angel Flight West Recognizes Colorado Pilots and Supporters at AFW 24th Anniversary Awards 2Health News:Study Determines Breast-Specific Gamma Imaging Has Higher Specificity Than MRI in Patients With Equivocal Mammograms 2Health News:Study Determines Breast-Specific Gamma Imaging Has Higher Specificity Than MRI in Patients With Equivocal Mammograms 3Health News:Aflac Announces Resignation of U.S. Marketing Officer 2Health News:Aflac Announces Resignation of U.S. Marketing Officer 3
(Date:1/15/2014)... Mass. , Jan. 15, 2014  Zafgen, ... the unmet needs of severely obese patients, today ... of beloranib, a selective inhibitor of methionine aminopeptidase ... a severe form of genetic obesity.  These results ... body composition, including reductions in body fat content ...
(Date:1/14/2014)... BEVERLY HILLS, Calif. , Jan. 14, 2014 ... , offers Los Angeles a premier ... Duality laser and a $99 treatment special. Dr. Brandeis, focus ... medical technology and offering expert medical advice to all patients. ... a dramatic increase in the presence of tattoo regret and ...
(Date:1/14/2014)... 2014 NineSigma , Inc., the leading ... Innovation Leadership Summit , May 14-16, 2014 at the ... Ohio . This is the ... to breakthrough achievements through open innovation. Participants will learn ... across disciplines and even across industries. ...
Breaking Medicine Technology:Zafgen Announces Initial Results from Phase 2a Study of Beloranib in Patients with Prader-Willi Syndrome 2Zafgen Announces Initial Results from Phase 2a Study of Beloranib in Patients with Prader-Willi Syndrome 3Zafgen Announces Initial Results from Phase 2a Study of Beloranib in Patients with Prader-Willi Syndrome 4Beverly Hills Physician Features Tattoo Removal with the Astanza Duality Laser, Offers $99 Special 2Expect the Unexpected from Leading Global Innovators at NineSigma Leadership Summit, Sharing Winning Strategies to Advance Innovation 2Expect the Unexpected from Leading Global Innovators at NineSigma Leadership Summit, Sharing Winning Strategies to Advance Innovation 3Expect the Unexpected from Leading Global Innovators at NineSigma Leadership Summit, Sharing Winning Strategies to Advance Innovation 4
... WINDSOR, N.J. , July 7 ITelagen, a leading ... it was selected by Zweena, LLC of West Windsor, NJ ... ITelagen, which was selected for its expertise in EHR management, is ... solution. , , , ...
... DENVER , July 7 Invision Sally Jobe ... a new breast ultrasound technology for the early detection of cancer. Screening ... in women with radiologically dense breasts and other risk factors. , ... "Screening breast ultrasound is part ...
Cached Medicine Technology:Zweena Selects ITelagen to Host Personal Health Records Application 2Zweena Selects ITelagen to Host Personal Health Records Application 3Invision Sally Jobe Introduces New Breast Cancer Screening Technology to Denver 2Invision Sally Jobe Introduces New Breast Cancer Screening Technology to Denver 3Invision Sally Jobe Introduces New Breast Cancer Screening Technology to Denver 4
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: