Navigation Links
Better Treatment Found for Crohn's Disease
Date:4/14/2010

Two drugs aimed at taming overactive immune system worked best, study found

WEDNESDAY, April 14 (HealthDay News) -- Combination therapy with two drugs that control an unruly immune system provided the best relief yet seen for Crohn's disease, a condition in which the body mistakenly attacks its own intestinal tissue.

The new finding promises to change current treatment of Crohn's disease, said study leader Dr. William J. Sandborn, vice chair of gastroenterology and hepatology at the Mayo Clinic in Rochester, Minn.

The results were reported in the April 15 issue of the New England Journal of Medicine.

Doctors now start treatment of Crohn's disease with steroids, Sandborn said. If the steroids do not provide relief from the abdominal pain, nausea, fever, weight loss, diarrhea and other symptoms of the condition, the next step is to use azathioprine, which reduces immune system activity broadly. Only if that fails will they try biologics, newer treatments that include monoclonal antibodies such as infliximab (Remicade). These drugs target a specific part of the immune system.

The trial showed that the azathioprine-alone step should be skipped. "This study suggests that the therapy that follows steroids should include a biologic," Sandborn added.

Therapy with both azathioprine and infliximab appears to be the treatment of choice if steroids are not effective, Sandborn said.

"What this trial shows is that the most effective strategy is combination therapy," he said.

The results will alter treatment of Crohn's disease to some extent, said Dr. Jeffrey A. Katz, a spokesman for the Crohn's and Colitis Foundation of America, but by and large "it really does confirm what other studies suggest and what is clinically apparent, that combination therapy is better than treatment with azathioprine alone."

"It will push me in the direction of using combination therapy a bit m
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved

Page: 1 2 3

Related medicine news :

1. Flu Vaccine With Both B Strains May Offer Better Protection
2. M. D. Anderson zeroes in on better way to predict prognosis in pediatric leukemia patients
3. Want better health information technology? Ask patients how they want it
4. Building a better flu vaccine: Add second strain of influenza B
5. Maintaining regular daily routines is associated with better sleep quality in older adults
6. Simple Forms Help Docs Do Better Breast Exams
7. My Health and Money Helps Consumers Stretch Their Healthcare Dollars and Make Better Choices
8. Discovery May Lead to Better Multiple Sclerosis Treatments
9. BHR Pharma Statement on Brain Injury Awareness Month - Better Awareness, Treatment, Research Needed Now
10. Pet Insurance Provider Hartville Group Gets A+ Rating From Better Business Bureau
11. The American Heart Association's The Heart of Diabetes Campaign is Helping Patients 'Know Your Diabetes' Better
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/22/2014)... By Alan Mozes ... -- Pediatricians, take note: Many American parents are aware of ... to choose a pediatrician for their children, according to a ... from more than 1,600 parents -- further suggest that negative ... if that doctor has been recommended by a neighbor. ...
(Date:9/22/2014)... partner in the Global STEM Alliance, a new high-tech ... science, technology, engineering and math (STEM) around the world. ... (NYAS), Malaysian Prime Minister Najib Razak participated in the ... the goal of developing over 1,000,000 aspiring STEM leaders ... will create a host of learning opportunities, including student ...
(Date:9/22/2014)... 22, 2014 An inventor and anesthesiologist ... the problem of side-sleeping. "My lower arm always became ... designed a solution to this problem," she said. "It’s ... to have your arm 'fall asleep.'" , The Sleeping ... her side more comfortably. It avoids pain and restlessness ...
(Date:9/22/2014)... Quincy Bioscience, one of the fastest-growing ... National Self-Improvement Month this September. The Wisconsin-based ... access to self-improvement resources, especially for maintaining healthy ... products that preserve health is growing as Americans ... six years, Quincy Bioscience has been promoting the ...
(Date:9/22/2014)... The Workgroup for Electronic ... authority on the use of health IT to ... from its recent industry survey on the use ... electronic transactions adopted under the Health Insurance Portability ... from August 20 to September 5, which included ...
Breaking Medicine News(10 mins):Health News:Many Parents Use Online Ratings to Pick a Pediatrician, Study Finds 2Health News:Many Parents Use Online Ratings to Pick a Pediatrician, Study Finds 3Health News:Growing scientists: World's future jobs are rooted in STEM 2Health News:Growing scientists: World's future jobs are rooted in STEM 3Health News:Quincy Bioscience Promotes National Self-Improvement Month 2Health News:WEDI Announces Survey Results from Unique Health Plan Identifier (HPID) Industry Poll 2Health News:WEDI Announces Survey Results from Unique Health Plan Identifier (HPID) Industry Poll 3
... can be predicted with the use of diffusion-weighted MRI ... at New York University Medical Center in New York, ... chronic hepatitis in the United States, particularly hepatitis C, ... replace or supplement liver biopsy, which is relatively invasive ...
... Allscripts (Nasdaq: MDRX ),the leading provider of ... to improve healthcare, announced today that,it will report ... ended September,30, 2007 after the stock market closes ... Standard Time on the same day, Allscripts management ...
... Oct. 23 After five,successful years of steady ... today that it is celebrating five years of,continued ... sales growth,that indicates reaching 100,000 orders by the ... ), "Our ReBuilder for Diabetic Peripheral Neuropathy ...
... YORK, October 23 Answers.com(TM) (NASDAQ:,ANSW) ... interactive health education,videos from HealthiNation, a ... health content on Answers.com. (See example ... to consumers in categories such as ...
... more information, more, expertise and more options in their ... Oct. 23 As more than 7,000 leaders and,providers ... Meeting and Exposition,of the American Association of Homes and ... in Orlando, Florida, to explore the future of aging,services, ...
... between parents ... and teens, INDIANAPOLIS, ... at preventing drunk driving and,underage drinking with new 30-second radio public service ... timed to,coincide with the busy fall season and will air 2,300 times ...
Cached Medicine News:Health News:MRI predicts liver fibrosis, study says 2Health News:Allscripts to Announce Third Quarter 2007 Results on November 8th 2Health News:Allscripts to Announce Third Quarter 2007 Results on November 8th 3Health News:ReBuilder Medical Technologies, Inc. Celebrates Five Years and 50,000th Shipment 2Health News:ReBuilder Medical Technologies, Inc. Celebrates Five Years and 50,000th Shipment 3Health News:Answers.com Adds HealthiNation Video Content to Answer Engine(TM) 2Health News:'Will You Still Love Me, Will You Still Need Me, When I'm 84?' 2Health News:Indiana Attorney General Steve Carter Addresses Drunk Driving and Underage Drinking in New Radio Campaign 2
(Date:9/22/2014)... , Sept. 22, 2014  Aethlon Medical, Inc. ... devices to address infectious disease, cancer and other ... Research Projects Agency (DARPA) has informed the Company ... proceed with year four of a five-year $5.9 ... September 30, 2011 under DARPA,s Dialysis-Like Therapeutics (DLT) ...
(Date:9/22/2014)... , Sept. 22, 2014 /PRNewswire/-- CANTEL MEDICAL CORP. (NYSE: ... quarter and fiscal 2014 ended July 31, 2014 on Monday, ... call to discuss the results at 11:00 AM ET. Participating ... Chairman; Andrew A. Krakauer , President and CEO; ... Craig A. Sheldon , Senior Vice President, CFO and Treasurer; ...
(Date:9/22/2014)... SAN FRANCISCO , Sept. 22, 2014  Sutro ... FierceBiotech as one of 2014,s Fierce 15 ... promising private biotechnology companies in the industry.  ... A-list group of backers as well as industry partners ... developing antibody-drug conjugates and bispecifics," says John Carroll ...
Breaking Medicine Technology:Aethlon Medical Receives Notice of DARPA Contract Renewal 2Aethlon Medical Receives Notice of DARPA Contract Renewal 3Aethlon Medical Receives Notice of DARPA Contract Renewal 4Cantel Medical Corp. To Hold Conference Call To Discuss Results For Its Fourth Quarter And Fiscal 2014 Ended July 31, 2014 2FierceBiotech names Sutro Biopharma as one of its "Fierce 15" Biotech Companies of 2014 2FierceBiotech names Sutro Biopharma as one of its "Fierce 15" Biotech Companies of 2014 3
... March 22 Cambrex Corporation (NYSE: ... a privately held company that is a leader in ... Wiesbaden, Germany and offers cost effective customized ... pharmaceutical industry, with the ability to utilize its tool ...
... Inc. (OTC Bulletin Board: GOVX), a biotechnology company that is developing and testing innovative HIV/AIDS vaccines, has engaged The Investor Relations Group ("IRG"), ... , ... , ... ...
Cached Medicine Technology:Cambrex Acquires IEP GmbH 2Cambrex Acquires IEP GmbH 3GeoVax Labs Engages The Investor Relations Group 2GeoVax Labs Engages The Investor Relations Group 3GeoVax Labs Engages The Investor Relations Group 4
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: