Navigation Links
Beta-blockers help reduce metastasis and improve survival in breast cancer patients
Date:3/26/2010

Barcelona, Spain: Treatment with beta-blockers can help reduce the spread of cancer in patients with breast tumours, a researcher will tell the seventh European Breast Cancer Conference (EBCC7) in Barcelona today (Friday). In a controlled study, Dr. Des Powe, a senior healthcare research scientist at Queen's Medical Centre, Nottingham University Hospital NHS Trust, Nottingham, UK, and his team found that the group of patients treated with beta-blockers showed a significant reduction in metastasis and better survival. The scientists believe that they are the first in the world to have investigated the effect of beta-blockers in breast cancer patients.

In collaboration with Professor Frank Entschladen's group at Witten University, Germany, Dr. Powe looked at three groups of breast cancer patients: those who were already being treated for hypertension by beta-blockers, those whose hypertension was treated by other medications, and those who did not suffer from hypertension and were therefore not taking any treatment for it. Forty-three of the 466 patients were already taking beta-blockers and, in this group, there were significant reductions in both distant metastasis and local recurrence. They also had a 71% reduced risk of dying from breast cancer compared with the other groups.

"We were also able to study the presence of one receptor for beta-blockers, β2AR, as a potential biomarker for predicting clinical response to beta-blocker treatment," says Dr. Powe, "but we did not find that this correlated directly to the outcome of treatment. We are currently looking at other target receptors as predictors of clinical outcome."

Previous cell line laboratory studies have shown that beta-blockers work against various types of cancer because high levels of stress hormones in the tumour increase cell proliferation and migration (the movement of cells to other locations). "These effects are induced by the stress hormones norepinephrine and e
'/>"/>

Contact: Mary Rice
mary@mrcommunication.org
ECCO-the European CanCer Organisation
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Stronger Ozone Standard Could Dramatically Reduce Asthma, Premature Deaths
2. Report documents statewide initiative to reduce near-term scheduled births
3. Gladstone scientists identify target that may reduce complications of obesity
4. Unique Clean Energy Program Helps Hospitals Buy Clean Energy, Reduce Costs and Counteract Climate Change
5. King Launches Painbalance: Educational Initiative to Help Reduce the Burden of Pain
6. Viscira Expands Interactive Solutions to Reduce Marketing Expenses for Pharmaceutical Companies in Challenging Economic Times
7. Abstinence-Only Classes Reduced Sexual Activity, Study Found
8. Study finds reduced brain gray matter concentration in patients with severe obstructive sleep apnea
9. CT Scans Reduce Unneeded Appendectomies in Women
10. Omega-3 Supplements Dont Reduce Risk of Preterm Birth
11. Attendance at Alcoholics Anonymous meetings may reduce depression symptoms
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/18/2014)... 2014 (HealthDay News) -- Daily supplements of selenium or ... development of age-related cataracts among men, a new study ... or both could help prevent cataracts. To investigate this ... Harvard Medical School in Boston, and his colleagues examined ... vitamin E. The trial was initially designed to study ...
(Date:9/18/2014)... (PRWEB) September 18, 2014 TayganPoint ... announced today that President and co-founder John Cassimatis ... Innovation Award Winners for 2014, recognizing the region’s ... as an emerging executive of the year. , ... and life sciences that continue to shape the ...
(Date:9/18/2014)... 2014 Stealth Health Revolution co-founders, ... and Frank Davis, founder of Food for Health ... pleased to announce the new recipe book, "The ... nutrition-packed meals using Activz whole-food powders." The ... in the Stealth Health Revolution mission ...
(Date:9/18/2014)... can expect to pay higher employee contributions for their ... resource officers about the impact of the Patient Protection ... Obamacare) conducted by the Darla Moore School of Business ... , Patrick Wright, a professor in strategic human resource ... HR Officers. The survey is distributed to more than ...
(Date:9/18/2014)... to develop tools that would allow them to clearly ... a neuron fires to the resulting behavior in a ... working to develop a range of new tools to ... such tool that provides a new way of mapping ... collaboration between Viviana Gradinaru (BS ,05), assistant professor of ...
Breaking Medicine News(10 mins):Health News:Vitamin E, Selenium Supplements Don't Seem to Prevent Cataracts 2Health News:TayganPoint Executive Receives Prestigious Award from Philadelphia Business Journal 2Health News:Montel Williams and Frank Davis Announce New Whole-Food Nutrition Recipe Book, The Simple Scoop, at Natural Products Expo East In Baltimore 2Health News:Montel Williams and Frank Davis Announce New Whole-Food Nutrition Recipe Book, The Simple Scoop, at Natural Products Expo East In Baltimore 3Health News:Survey: Fortune 500 employees can expect to pay more for health insurance 2Health News:Survey: Fortune 500 employees can expect to pay more for health insurance 3Health News:Sensing neuronal activity with light 2Health News:Sensing neuronal activity with light 3Health News:Sensing neuronal activity with light 4Health News:Sensing neuronal activity with light 5
... much about it. FlameEz.com is launched to provide the latest information ... of the most feared illnesses in middle and old age. ... ... Millions of Americans are affected by chronic inflammation without knowing much ...
... a ,must book-mark site,BETHESDA, Md., Jan. 14 The ... Foundation,s Web site -- www.cff.org -- the ... its "Best of the Web" review of 2008, the ... about cystic fibrosis. , , "This ...
... in French Hospital Market with More Than 130 ... ("Global Med" or the "Company") (OTC Bulletin Board: ... today announced that its subsidiary, Inlog, has licensed ... Serveur" in France) to nineteen additional hospitals during ...
... to Treat Diseases (HTDS) www.htdsmedical.com management ... agreement with Shenzhen Mellow Hope Pharm Industrial Co., ... biggest exporter of Biological Vaccines in China, and ... influenza, tetanus, diphtheria and other diseases; Blood based ...
... Quality Program ReviewsSEATTLE, Jan. 14 MetaStar, ... clinical guidelines and software from Milliman Care ... non-physician medical care reviews throughout the state. ... Milliman Care Guidelines (R) suite, MetaStar now ...
... insulin and oral human growth hormone formulations provide ... ACCESS PHARMACEUTICALS, INC. (OTC Bulletin Board: ... Cobalamin(TM) oral drug delivery product development programs. The ... B12 oral uptake mechanism to facilitate oral absorption ...
Cached Medicine News:Health News:Control of Inflammation May Benefit Many of the Most Feared Illnesses in Middle and Old Age 2Health News:Control of Inflammation May Benefit Many of the Most Feared Illnesses in Middle and Old Age 3Health News:Cystic Fibrosis Foundation Web Site Rated 'Best of the Web' 2Health News:Global Med Technologies(R)' Inlog Subsidiary Licensed EdgeTrack to 62 French Hospitals in 2008, Including 19 Hospitals in Q4 2008 2Health News:Global Med Technologies(R)' Inlog Subsidiary Licensed EdgeTrack to 62 French Hospitals in 2008, Including 19 Hospitals in Q4 2008 3Health News:Hard To Treat Diseases (HTDS) in Merger Talks with Mellow Hope, China 2Health News:Milliman Care Guidelines(R) Replaces Multiple Guideline Sets for Wisconsin QIO 2Health News:Milliman Care Guidelines(R) Replaces Multiple Guideline Sets for Wisconsin QIO 3Health News:Access Pharmaceuticals Provides an Update on Advances In Its Cobalamin(TM) Oral Drug Delivery Product Development 2Health News:Access Pharmaceuticals Provides an Update on Advances In Its Cobalamin(TM) Oral Drug Delivery Product Development 3
(Date:9/18/2014)... , Sept. 18, 2014  Decision Resources Group ... the United States , 54 percent ... BRAF inhibitor Tafinlar for BRAF -mutation-positive unresectable ... have prescribed GlaxoSmithKline,s MEK inhibitor Mekinist. Among current ... (42 percent and 43 percent, respectively) expects to ...
(Date:9/18/2014)... , Sept. 18, 2014  ADM Tronics ... DeNovi , Ph.D. to its corporate Advisory Board ... an instructor at the Harvard Medical School and ... Rome.  He received his Masters degree in Electronics ... Systems from the University of Bologna. After spending a ...
(Date:9/18/2014)... , Sept. 18, 2014  A $3 million grant ... the University of Michigan to establish a national center ... Glenn Center for Aging Research at U-M will focus ... can slow the effects of aging and postpone diseases ... aging that can help develop medications that may help ...
Breaking Medicine Technology:At One Year Post-Launch, Approximately One Half of Surveyed U.S. Medical Oncologists Have Prescribed Single-Agent Tafinlar and Mekinist to Their Malignant Melanoma Patients 2ADM Tronics Appoints Gianluca DeNovi, Ph.D. To Advisory Board 2ADM Tronics Appoints Gianluca DeNovi, Ph.D. To Advisory Board 3$3 M grant funds Paul F. Glenn Center for Aging Research at the University of Michigan 2$3 M grant funds Paul F. Glenn Center for Aging Research at the University of Michigan 3
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: