Navigation Links
Beta Blockers Help Hospitalized Heart Failure Patients

Continuing treatment reduces death risk, rehospitalization rates, study finds

FRIDAY, July 11 (HealthDay News) -- People who are hospitalized for severe heart failure and have been taking beta blockers should be kept on those medications while in the hospital, a new study finds.

And if they weren't taking beta blockers already, most of them should be started on the medications when they leave, according to a report in the July 15 issue of the Journal of the American College of Cardiology.

The multi-center study of 2,373 people with heart failure severe enough for them to suffer decompensated heart failure, in which they suffer fluid retention, shortness of breath and other complications, is the latest in the back-and-forth story about the role of beta blockers in heart failure, which is the progressive loss of the heart's ability to pump blood.

Beta blockers reduce the activity of adrenaline, and so make the heart beat slower. It was first thought that they were no help against heart failure, said Dr. James B. Young, chairman of the department of medicine at the Cleveland Clinic Lerner College of Medicine and a member of the research team, but experience has shown otherwise. They now are widely prescribed for the condition.

"But many questions abound, including the best treatment strategy in the hospital," Young said. "The best treatment strategy has been hard to define for hospitalized patients. These are tough questions we haven't had a lot of evidence about."

The new study shows a clear benefit for continuing the drug. More than half of the people hospitalized for heart failure were already taking beta blockers. Continuing that drug therapy reduced the risk of death by 40 percent and of going back into the hospital by 31 percent. Discontinuing beta blocker therapy more than doubled the risk of death.

"This is a very important message that beta blockers are an important therapy for heart failure," said Dr. Mihai Gheorghiade, a professor of medicine at Northwestern University Feinberg School of Medicine and a member of the research group.

Gheorghiade was a leader of a study several years ago which showed that hospitalized heart failure patients who were not taking beta blockers benefited from having the therapy started before they left the hospital. The new study supports the view that "it is safe and effective to start beta blockers before discharge," at least in most cases, he said.

"If there are severe signs and symptoms before discharge, you have to think twice," Gheorghiade said. "A patient who is not severely decompensated, with a heart rate below 40 or 50, you can start the drug before discharge."

The new study could have a wide application, Young noted. About 1 million Americans are hospitalized each year because of heart failure, he said. And it marks a complete reversal in what was once the common belief, that beta blockers would harm people with heart failure.

"If you are on a beta blocker and are admitted with decompensated heart failure, it is best not to stop the drug, as had been commonly thought recently," Young said.

More information

Learn about beta blockers and other drugs for heart failure from the American Heart Association.

SOURCES: James B. Young, M.D., chairman, department of medicine, Cleveland Clinic Lerner College of Medicine, Ohio; Mihai Gheorghiade, M.D., professor, medicine, Feinberg School of medicine, Northwestern University, Chicago; July, 15, 2008, Journal of the American College of Cardiology

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Scripps scientists find calcium channel blockers help normalize lysosomal storage disease cells
2. Women are treated less frequently than men with statins, aspirin and beta-blockers
3. Beta Blockers Raise Stroke, Death Risk After Surgery
4. Chicago Bears Players Visit Hospitalized Veterans
5. Antivirals reduce deaths from flu in hospitalized patients
6. Rapid Response Teams Can Save Hospitalized Kids
7. Drug Mix-Ups Harm Hospitalized Kids
8. Los Angeles Ronald McDonald House Doubles Lodging Capacity for Families of Hospitalized Children
9. JCSM: A high frequency of sleep-related breathing disorders in hospitalized patients
10. Young Children Hospitalized for Flu Associated With Higher Costs and Higher Risk Illness
11. Young children hospitalized for flu associated with higher costs and higher risk illness
Post Your Comments:
Related Image:
Beta Blockers Help Hospitalized Heart Failure Patients 
(Date:11/25/2015)... ... November 25, 2015 , ... Today, Mothers Against Drunk ... roadways has dropped below 10,000 for the first time since 2011. In 2014, there ... According to data released by the National Highway Traffic Safety Administration (NHTSA), 32,675 people ...
(Date:11/25/2015)... ... ... An unlikely combination of recycled plastic shopping bags in ... to have a more dignified and comfortable night’s sleep. , Residents of Friendship ... bags into sleeping mats for the homeless. The project, according to Jeannette ...
(Date:11/25/2015)... CA (PRWEB) , ... November 25, 2015 , ... ... bunion treatment, is offering lower prices in an early celebration of the early ... the promotional price of $29.95 each (normally $33.95 ea). Black Friday promotional pricing ...
(Date:11/24/2015)... ... November 24, 2015 , ... Young patients with a wide variety ... Wolfman and Dr. Kedar S. Lele, who are pediatric dentists in Tucson, AZ ... the WaterLase iPlus 2.0™ system causes minimal discomfort and bleeding to the patient during ...
(Date:11/24/2015)... ... , ... DMG Productions announced that they will feature Aphria, Inc., in an ... Channel. Dates and show times TBA. , Aphria, Inc., is a publicly traded company ... and supplying medical marijuana pursuant to the Marijuana for Medical Purposes Regulations (the “MMPR”). ...
Breaking Medicine News(10 mins):
(Date:11/24/2015)... , November 25, 2015 The ... to repeated failure of IVF cycles. After failure of ... dejected and had lost all hopes that she would be able to ... miracle child conceived after failure of over 15 IVF ... (UK) before they decided to take one last attempt with Gaudium ...
(Date:11/24/2015)... CARLOS, Calif. , Nov. 24, 2015 ... a leader in non-invasive genetic testing and ... announced that it will present at the ... in New York on Wednesday, December 2, 2015 at 1:00 p.m. ET.  Matthew ... the Company,s financial results, business activities and ...
(Date:11/24/2015)... TX and VANCOUVER, Nov. 24, 2015 /PRNewswire/ - ... NASDAQ: EPIX ) announced today that the first ... study of EPI-506 as a treatment for metastatic castration-resistant ... and Canada.  --> ... --> In the Phase 1/2 clinical trial, ESSA ...
Breaking Medicine Technology: