Navigation Links
Berkeley Lab scientists find that normal breast cells help kill cancer cells
Date:4/13/2011

It is well known that the human body has a highly developed immune system to detect and destroy invading pathogens and tumor cells. Now, researchers at the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) have shown that the body has a second line of defense against cancer healthy cells. A new study shows that normal mammary epithelial cells, as they are developing, secrete interleukin 25, a protein known for its role in the immune system's response to inflammation, for the express purpose of killing nearby breast cancer cells.

"We found that normal breast cells provide an innate defense mechanism against cancer by producing interleukin 25 (IL25) to actively and specifically kill breast cancer cells," says breast cancer authority Mina Bissell, of Berkeley Lab's Life Sciences Division, who led this research. "This suggests that IL25 receptor signaling may provide a new therapeutic target for the treatment of breast cancer."

The results of this research are reported in the journal Science Translational Medicine in a paper titled "IL25 Causes Apoptosis of IL25R-expressing Breast Cancer Cells Without Toxicity to Nonmalignant Cells." Co-authoring the paper with Bissell were Saori Furuta, Yung-Ming Jeng, Longen Zhou, Lan Huang, Irene Kuhn and Wen-Hwa Lee, of the University of California, Irvine, who along with Bissell is a corresponding author.

Although cancer remains a leading cause of premature death in the world today, most people live cancer-free lives for decades. In fact, the rate of cancer disease in the human population is surprisingly low given that the cells in our bodies are exposed on a daily basis throughout our lifetimes to radiation and chemical damage, plus a host of other factors that promote harmful DNA mutations and malignant tumors. It is not as if mutant cells are not being generated, explains Saori Furuta, lead author of the Science Translational Medicine paper and a Berkeley L
'/>"/>

Contact: Lynn Yarris
lcyarris@lbl.gov
510-486-5375
DOE/Lawrence Berkeley National Laboratory
Source:Eurekalert  

Page: 1 2 3 4

Related medicine news :

1. UCSF, UC Berkeley join forces to advance frontier of brain repair
2. Conference highlights UC Berkeleys unique approach to green chemistry
3. Firefly glow: Berkeley Lab scientists develop a hydrogen peroxide probe based on firefly luciferin
4. Berkeley study shows ozone and nicotine a bad combination for asthma
5. UC Berkeley psychologists bring science of happiness to China
6. Lawrence Berkeley National Laboratory and OpenHelixTM Announce an Updated Free Tutorial Suite for VISTA: Tools for Comparative Genomics
7. Artery Plaque Forms in Short Time Span, Scientists Say
8. Scientists Complete Detailed Map of Human Brain
9. Feinstein scientists identify abnormal disease pathway in dystonia
10. Scientists find potential benefit of hypericin for recurrent brain tumors
11. Scientists Use Computer to Read Human Thoughts
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Berkeley Lab scientists find that normal breast cells help kill cancer cells
(Date:8/30/2014)... Market Research Report on Global and ... and in-depth market survey on Global and Chinese ... basic information of Lab Oven including its classification, ... global and China’s top manufacturers of Lab Oven ... market share etc. , The report further analyzes ...
(Date:8/30/2014)... 2014 Bringing forth the great opportunities, ... announces the Labor Day discount on all SEO services. ... the complete services related to internet marketing. Their dedicated ... and others do have a deep understanding for their ... their work and since the inception, they have worked ...
(Date:8/30/2014)... 2014: Transvenous lead extraction (TLE) is clinically successful in ... the European Lead Extraction ConTRolled (ELECTRa) registry presented for ... Dr Maria Grazia Bongiorni, chair of the registry,s executive ... implantable electronic devices (CIED) implant procedures has grown in ... complications has increased and leads are often the cause. ...
(Date:8/30/2014)... 2014 One of the most recent dietary ... gluten-free diet. Originally meant for sufferers of gluten intolerance and ... people who are looking to get healthier by simply consuming ... this kind of information erroneous, it also exposes those same ... of a drastic change in their food consumption habits. ...
(Date:8/30/2014)... 2014 Removecomplaints.net, a well-known name in ... announced to offer guarantee of results with its complaint ... guarantee because of its tremendous track record. The company ... all over the world and received recommendation letters from ... , On being asked about the announcement, a senior ...
Breaking Medicine News(10 mins):Health News:Lab Oven Industry for Global and Chinese Market Forecasts to 2019 in New Research Report Available at ReportsnReports.com 2Health News:Lab Oven Industry for Global and Chinese Market Forecasts to 2019 in New Research Report Available at ReportsnReports.com 3Health News:Lab Oven Industry for Global and Chinese Market Forecasts to 2019 in New Research Report Available at ReportsnReports.com 4Health News:Profit By Search Announces Labor Day Discount on SEO Services 2Health News:Transvenous lead extraction clinically successful in 98 percent of cases 2Health News:Transvenous lead extraction clinically successful in 98 percent of cases 3Health News:“What is Gluten: Three Things You Need to Know Before Adopting a Gluten-Free Diet” Reveals What Readers Need to Know About the Benefits of a Strict Gluten Diet - Vinamy 2Health News:Removecomplaints.net Announces Guaranteed Complaints Removal Services 2
... has been a recent increase in the number of men who ... . The number of men undergoing nip and tuck surgery has ... the most common. ,The phenomenon has been dubbed the 'menopaunch' ... ,The men seem to be facing pressures as women to look ...
... and body, a rare medical anomaly. And doctors say that laser ... ,Prithviraj Patil, son of a well-to-do farmer in Sangalwadi near ... like any normal child. ,,Prithiviraj has no problem with his ... awful - there is no itch or rash on the skin ...
... that was rare three decades ago has surged in the ... Medical Association (JAMA) found . ,The cancer known ... United States in the decades between 1973 and 2002, according ... Dermatology, which is part of JAMA. ,"The overall ...
... Monday upheld a ban on a teenager from wearing a so-called ... marriage. ,Lydia Playfoot, 16, said she was "disappointed" ... Millais School in Horsham, West Sussex, denies infringing her human rights, ... Christian faith and violates its uniform policy. ,"As a ...
... dramatically lower the rapidly rising costs of several anticancer ... suggest in a commentary in the Journal of ... Ratain, MD, and Ezra Cohen, MD, call attention to ... foods can alter absorption or delay breakdown of precisely ...
... not complying with their dermatologic treatment is a ... to Steven Feldman, M.D., Ph.D., from Wake Forest ... published in the current issue of Archives of ... why some conditions may seem resistant to treatment. ...
Cached Medicine News:Health News:Men Under Knife to Reduce Bulging Waistline in Britian 2Health News:Hairy Boy Bets on Laser Treatment for Cure 2Health News:Value Meal Would Lower Drug Costs 2Health News:Value Meal Would Lower Drug Costs 3Health News:Patients Not Complying With Their Dermatologic Problem 2Health News:Patients Not Complying With Their Dermatologic Problem 3
(Date:8/29/2014)... MENLO PARK, Calif. , Aug. 29, 2014 /PRNewswire/ ... Medina Medical as CEO and member of the Board ... three decades of medical device development and commercialization experience, ... Medical,s field. Mr. Engelson previously served as a Partner ... served as President and CEO of two Foundry start-ups. ...
(Date:8/29/2014)... DUBLIN , Aug. 29, 2014 ... the "Global Peptide Cancer Therapeutics Market & Pipeline ... The conventional methods developed to prevent and eradicate ... cancer treatment. These methods are confined to low specificity, ... the researchers to look for a better solution. It ...
(Date:8/29/2014)... , Aug. 29, 2014 Research ... "Research and Development Trend Forecast of Pharmaceutical Equipment ... Research and Development Trend Forecast of ... 2014-2018 mainly analyzes China,s pharmaceutical ... supply & demand, competition landscape, and business performance of ...
Breaking Medicine Technology:Medina Medical Announces Erik T. Engelson Joins as Chief Executive Officer 2Global Peptide Cancer Therapeutics Market & Pipeline Insight 2014 2Research and Development Trend Forecast of Pharmaceutical Equipment Market in China, 2014-2018 2
... Premium Low Binding, Graduated Pipet Tips - 2l ... Beveled and referenced. Produced & packaged completely by ... Sterile Racked packaged 96 tips/rack and 10 racks/cs. ... and 10 racks/cs. AVR3 is the Stacked Rack ...
... ART Aerosol Resistant Tips offer a ... ART Tips are designed for applications such ... studies. In addition, ART Tips are excellent ... and forensic studies. ART Tips prevent aerosol ...
200 L, Racked, Pre-sterilized, 96 tips/rack Recommended for 20, 25, 50, 100 and 200 L pipettes. Can also be used with 300 L pipettes when pipetting 200 L or less....
... Packed conveniently in plastic-wrapped racks of 96 ... useno need to autoclave. Sterilized Diamond Tips ... sterilization and are delivered with a certificate ... Sterilized Diamond Tips are certified free of ...
Medicine Products: