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Berkeley Lab scientist co-leads breast cancer 'dream team'
Date:5/27/2009

le example of its use, a sample of a patient's tumor could be molecularly analyzed in a lab. This information could then be sent via a secure web connection to a cancer genomics database and analyzed by Dream Team members, who recommend the best therapy to the patient's physician.

Gray believes the time is right for this integrated approach. In recent years, thanks to landmark research initiatives such as the Human Genome Project, scientists have made great strides in learning what goes wrong at the molecular and genomic level in different types of cancers. At the same time, pharmaceutical companies are developing hundreds of therapeutic agents to fight cancer, some of which will be effective against some types of cancer, some against others. The next step is bringing these two worlds together.

"We need to match individual cancers with specific therapies, and bring personalized cancer treatment to the clinic where it can save lives," says Gray.

In addition to Gray and Slamon, the principal investigators of the Breast Cancer Dream Team include Arul Chinnaiyan of the University of Michigan, David Haussler of UC Santa Cruz, Peter Sorger of Harvard Medical School, Terence Speed of UC Berkeley, Zena Werb of UC San Francisco, Alan Ashworth, Joan Brugge of Harvard Medical School, Gregory Hannon of Cold Spring Harbor Laboratory, Craig Jordan of Fox Chase Cancer Center, Kent Osborne of Baylor College of Medicine and Max Wicha of the University of Michigan Comprehensive Cancer Center.


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Contact: Jeff Miller
jwmiller@lbl.gov
510-486-6601
DOE/Lawrence Berkeley National Laboratory
Source:Eurekalert

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