Navigation Links
Benji, Marley or Bo: Three Genes Dictate Dog's Coat
Date:8/27/2009

Findings could have implications for study of human genetics and disease

THURSDAY, Aug. 27 (HealthDay News) -- New research shows that only three genes are responsible for all seven types of coats found in purebred dogs.

So, whether a dog is curly-haired like Bo, President Obama's pooch, or long-haired like Lassie, variations of the genes RSPO2, FGF5 and KRT71 are responsible, according to a U.S. National Institutes of Health study published online Aug. 27 in the journal Science. The findings may also point the way toward understanding complex human diseases caused by multiple genes.

In an analysis of 80 domestic breeds that included over 1,000 dogs, it was discovered that RSPO2 is the gene associated with whether or not a dog has a mustache and large eyebrows (known as "furnishings"), FGF5 determines if a dog has short or long fur, and KRT71 is associated with being curly or wavy.

Other findings from the study include:

  • Australian terriers and other wire-haired dogs have a variant form of the RSPO2 gene only.
  • Airedale terriers and other dogs with wiry and curly hair have variants of the RSPO2 as well as the KRT71 gene.
  • Golden retrievers and similar long-haired dogs have a variant form of the FGF5 gene.
  • Bearded collies and other long-haired dogs with furnishings have variant forms of FGF5 and RSPO2.
  • Portuguese water dogs, like Bo, come in curly and wavy varieties, depending on the form of the KRT71 gene.

The study, conducted at the University of Utah, also found connections between the overall health of a breed and the kind of coat for which it was bred. Dogs bred for a desired trait may become more vulnerable to cancer, immune disorders or other diseases of aging, the researchers noted in a news release from the university.

"Ultimately the most important part of this paper . . . is that we will be able to get glimpses of how major regulatory genes interact with other genes to change the functioning of an animal in a way that does not kill it, but that may eventually compromise its longevity or its functioning as it ages," K. Gordon Lark, a study author and a distinguished professor emeritus of biology at the University of Utah, said in the news release.

More information

The American Kennel Club offers details on the characteristics of different dog breeds.



-- Peter West



SOURCE: University of Utah, news release, Aug. 27, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Plexus Systems Ranks in Top Third of the 2007 Inc. 5,000 with Three-Year Sales Growth of 226%
2. Best Practice Database: Complimentary Excerpt of Three Sales Force Excellence Studies
3. Lorus Therapeutics announces election of three new Directors and appoints a new Chairman
4. Portico Systems Wins Three Awards in 30 Days
5. Three Batesville Casket Company Production Facilities Honored for Manufacturing Expertise by National Organizations
6. Unions File Charges Against Tenet Healthcare Corporation, Three Northern California Hospitals
7. AISHealth.com Introduces Three New Free Services: Health Business Daily Newsletter, Health Business Meeting Calendar, and Health Care Job Openings
8. Sign Up Now for Project Management Essentials - Three Days of Training in IT Project Management Fundamentals
9. Medco Unveils Three New Medicare Prescription Drug Plan Options for 2008 to Provide Seniors More Choice, Better Value and Specialist Pharmacists
10. ReBuilder Medical Technologies, Inc. Increases Staffing by 30% in Three Weeks Due to Increase in Demand for All ReBuilder Medical Products
11. Brain, Eye and Heart Health: Three Reasons to Eat More Omega-3s
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Benji, Marley or Bo:  Three Genes Dictate Dog's Coat 
(Date:5/24/2017)... ... May 24, 2017 , ... Technique, technique, technique – with a dash ... weights for strength training and exercise or simply lifting heavy objects, advises Dr. Kaliq ... is everything,” Dr. Chang says. “Improper technique in lifting anything heavy or an attempt ...
(Date:5/23/2017)... New York City (PRWEB) , ... May 23, ... ... Record (EHR), Population Health and Clinical Integration company, announced today that its ... Patient-Centered Medical Home (PCMH) 2017 Prevalidation. NCQA recently introduced PCMH 2017 standards ...
(Date:5/23/2017)... PITTSBURGH, Pa. (PRWEB) , ... May 23, 2017 , ... ... today plans to open The Alexis Joy D’Achille Center for Women’s Behavioral Health at ... state-of-the-art care available in western Pennsylvania for women suffering from pregnancy-related depression. Construction ...
(Date:5/23/2017)... , ... May 23, 2017 , ... ... North Carolina have remained steady since 2009, according to a Workers Compensation Research ... The study Monitoring the North Carolina System: CompScope™ Benchmarks, 17th Edition ...
(Date:5/23/2017)... ... May 23, 2017 , ... i2i Population ... Best in KLAS category winner, has named Daniel P. Bullington as chief technology ... its technology platform and product offerings,” says Justin Neece, president. “Daniel is an ...
Breaking Medicine News(10 mins):
(Date:5/15/2017)... , May 15, 2017 Enterin Inc., a privately-held ... and developing novel compounds to treat Parkinson,s disease (PD), has ... is a Phase 1/2a randomized, controlled, multicenter study involving patients ... will enroll 50 patients over a 9-to-12-month period. The first ... 10 patients with PD. Participating sites include Denver ...
(Date:5/10/2017)... Mass., May 10, 2017 Hologic, Inc. (Nasdaq: ... results for the fiscal second quarter ended April 1, ... of $1.84 increased 666.7% compared to the prior year ... resulted in a significant gain, while non-GAAP diluted EPS ... 3.2%, or 3.8% in constant currency terms.  Excluding the ...
(Date:5/10/2017)... , May 10, 2017 Radiology has become ... its costs have also spiraled to the number one ... to radiology than ever before as the most complete ... a patient with lower back pain an MRI may ... reason for pain, resulting in entirely different treatment protocols.  ...
Breaking Medicine Technology: