Navigation Links
Benign or cancerous? Gene test predicts cancer potential in pancreatic cysts
Date:7/20/2011

cancer, as well as cells in the cysts.

GNAS and KRAS mutations were not found in benign cysts, although KRAS mutations did appear occasionally in a rare type of cyst with a relatively low potential to become cancerous. These rare, mostly benign cysts are less challenging to diagnose because of their location within the pancreas and type of patient, according to the investigators.

"There has long been a need for accurate, quantitative ways to identify cysts that are more worrisome and to help patients avoid unnecessary surgeries for harmless cysts," says Vogelstein, the Clayton Professor of Oncology at the Johns Hopkins Kimmel Cancer Center.

"Most cysts are benign," says pathologist Ralph Hruban, M.D., director of Hopkins' Sol Goldman Pancreatic Cancer Research Center, "but distinguishing between the harmless and dangerous ones is challenging for doctors and patients alike."

Generally, patients with a cyst that appears harmless and is less than 3 cm in size are monitored to watch for growth of the cyst or other concerning features such as a solid nodule. With cysts that appear more worrisome, surgical removal is often recommended, but the procedure requires removal of a portion of the pancreas as well, and complications like a pancreatic fistula (fluid from the pancreas leaks through the surgical incision), eating difficulties and prolonged recovery can develop, according to Christopher Wolfgang, M.D., Ph.D., associate professor of surgery, pathology and oncology and director of pancreatic surgery at Johns Hopkins.

CT scans, MRI imaging, and enzyme and secreted antigen levels in cyst fluid are imprecise markers for precancerous potential, adds Wolfgang.

Genetic analysis of the kind reported in the new study offers a new way to sort the potential of these cysts to cause malignant trouble.

The investigators caution that cyst fluid removal, an invasive procedure, also has its caveats and can cause bleeding
'/>"/>

Contact: Vanessa Wasta
wasta@jhmi.edu
410-614-2916
Johns Hopkins Medical Institutions
Source:Eurekalert  

Page: 1 2 3

Related medicine news :

1. Brain Surgery for Mary Tyler Moore to Remove Benign Tumor
2. Research finds surgery outperforms drug therapy in treatment of benign prostatic hyperplasia
3. Hormone test predicts ovarian function after chemotherapy for breast cancer
4. Earlier PSA Test Best Predicts Risk of Dying From Prostate Cancer: Study
5. VCU Massey Cancer Center finds new biomarker that predicts breast cancer relapse
6. Gene expression predicts chemotherapy sensitivity of triple-negative breast cancer
7. Climate change analysis predicts increased fatalities from heat waves
8. HIV rate in SF could be cut sharply with expanded treatment, study predicts
9. New lung cancer staging system (TNM 7) better predicts local/regional recurrence, study shows
10. Interest in toys predicts effectiveness of autism treatment in toddlers
11. New online tool predicts probability of death from stroke
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Benign or cancerous? Gene test predicts cancer potential in pancreatic cysts
(Date:8/3/2015)... ... August 03, 2015 , ... The ... (ICC) announce an agreement to collaborate across a wide range of initiatives ... building code knowledge among architects. , “Our combined membership, consisting of practicing design ...
(Date:8/2/2015)... ... August 03, 2015 , ... A new Phase I research study is ... study is led by Kenneth G. Lucas, M.D. , chief of the division ... with colleagues at Kosair Children’s Hospital and in the UofL Department ...
(Date:8/1/2015)... (PRWEB) , ... August 02, 2015 , ... AlignLife ... which will help the continuity of care for patients at this natural health care ... the unknown," Clinic Director Mary Heal said. "Heather's role is vital to our approach ...
(Date:8/1/2015)... ... 01, 2015 , ... The condition where veins are enlarged and gnarled is ... pain and discomfort. Those who spend a lot of time on their feet and ... is doing what it can to create awareness and provide a cure in observance ...
(Date:8/1/2015)... Greenwich, CT (PRWEB) , ... August 01, 2015 ... ... Great Point Partners I, L.P. (“GPP”) portfolio company has acquired Premier Physical Therapy ... incorporating it into its portfolio of state-of-the-art clinics. , “Our acquisition of Premier ...
Breaking Medicine News(10 mins):Health News:Architects, International Code Council Ink Five-Year Collaborative Agreement 2Health News:Architects, International Code Council Ink Five-Year Collaborative Agreement 3Health News:UofL Physicians Conducting Vaccine Trial for Children with Relapsed Tumors at Kosair Children’s Hospital 2Health News:New Patient Advocate Enhances Natural Health Care 2Health News:Northeast Houston Vein Center Warns Men about Varicose Veins 2Health News:Northeast Houston Vein Center Warns Men about Varicose Veins 3Health News:Professional Physical Therapy Now Largest Outpatient Physical Therapy Provider in Northeast With Acquisition of Premier Physical Therapy & Wellness 2
... ARLINGTON, Va., Dec. 2 From more than 1,100 photos ... and peace, the LIFE Foundation has selected six winners in ... flickr.com. The winning photos can be viewed in a video ... . , Contestants submitted one photo and a caption ...
... , American Red Cross also ... WASHINGTON, Dec. 2 The Hewlett-Packard Company Foundation has contributed ... Red Cross disaster response. , (Logo: http://www.newscom.com/cgi-bin/prnh/20090108/RedCrossLOGO ) ... Philippine communities affected by typhoons in September and October. Other ...
... , WASHINGTON and REDMOND, Wash., Dec. 2 ... announced the companies will collaborate to give caregivers single-point access ... after patients leave the hospital and to give patients and ... Living is the first post-acute care organization to adopt Microsoft ...
... to life span in males , WEDNESDAY, Dec. 2 (HealthDay ... and other mammals and could help explain why females tend ... researchers found that mice created using two female genomes -- ... than mice created from the normal combination of a male ...
... found drinking five or more per week prior to ... (HealthDay News) -- Women who drink five or more ... increase their risk of developing diabetes during pregnancy, a ... association with other chronic metabolic problems," said study author ...
... , LONDON, Dec. ... of improved therapies to treat lifestyle disorders. In the near ... witness enhanced therapies and novel drugs to treat such conditions ... ) , New analysis from Frost & Sullivan ( http://www.pharma.frost.com ...
Cached Medicine News:Health News:Wonders of Life Photo Contest Winners Announced 2Health News:Wonders of Life Photo Contest Winners Announced 3Health News:Hewlett-Packard Company Foundation Donates $1 Million for Red Cross Disaster Response 2Health News:Hewlett-Packard Company Foundation Donates $1 Million for Red Cross Disaster Response 3Health News:Golden Living Kick-Starts Post-Acute Health IT with Microsoft HealthVault and Amalga UIS Connection 2Health News:Golden Living Kick-Starts Post-Acute Health IT with Microsoft HealthVault and Amalga UIS Connection 3Health News:Golden Living Kick-Starts Post-Acute Health IT with Microsoft HealthVault and Amalga UIS Connection 4Health News:Sperm Gene May Cause Men's Longevity Disadvantage 2Health News:Sugary Colas Tied to Gestational Diabetes 2Health News:Sugary Colas Tied to Gestational Diabetes 3Health News:Development of Newer Therapies to Treat Lifestyle Disorders and Reduce the Risk of Co-morbidities is Key to the Expansion of the European Lifestyle Disorders Therapeutics Market, Says Frost & Sullivan 2Health News:Development of Newer Therapies to Treat Lifestyle Disorders and Reduce the Risk of Co-morbidities is Key to the Expansion of the European Lifestyle Disorders Therapeutics Market, Says Frost & Sullivan 3
(Date:7/31/2015)...  Seeger Weiss LLP is reporting that on July 13, ... to C.R. Bard, the manufacturer of Inferior vena cava ... violations the agency found at two of Bard,s facilities. Bard ... cited them during Inspectional Observations that occurred on November 18, ... AZ , location and on October 6, 2014, through ...
(Date:7/31/2015)... , July 31, 2015 Today, ... (NABP ® ) issued a report urging ... that action is taken against websites illegally selling ... Internet Drug Outlet Identification Program Progress Report for ... , thousands of websites illegally distribute medications ...
(Date:7/31/2015)... , July 31, 2015 The Physician-Patient ... release on July 28, 2015, "Surviving Your Hospital ... Fundraising for Patient Safety." A sentence ... should read: "PPAHS is a member ... on Opioids. For more information on the National Coalition ...
Breaking Medicine Technology:Seeger Weiss LLP Reports That The FDA Has Issued A Warning Letter To IVC Filter Manufacturer, C.R. Bard 2Seeger Weiss LLP Reports That The FDA Has Issued A Warning Letter To IVC Filter Manufacturer, C.R. Bard 3NABP Stresses Need for Accountability in Enforcing Internet Policies to Protect the Public From Illegal Online Drug Sellers 2NABP Stresses Need for Accountability in Enforcing Internet Policies to Protect the Public From Illegal Online Drug Sellers 3
... NEW YORK, Oct. 6, 2011 ... research report is available in its ... Market Outlook in Sweden to 2016 ... Imaging Information Systems ...
... Oct. 6, 2011 Echo Therapeutics, Inc. ... Symphony tCGM System as a non-invasive, wireless, transdermal continuous ... for transdermal drug delivery, today announced positive results from ... from the study confirm that Symphony successfully monitors patient ...
Cached Medicine Technology:Healthcare IT Market Outlook in Sweden to 2016 - Hospital Information Systems and Medical Imaging Information Systems 2Healthcare IT Market Outlook in Sweden to 2016 - Hospital Information Systems and Medical Imaging Information Systems 3Healthcare IT Market Outlook in Sweden to 2016 - Hospital Information Systems and Medical Imaging Information Systems 4Healthcare IT Market Outlook in Sweden to 2016 - Hospital Information Systems and Medical Imaging Information Systems 5Healthcare IT Market Outlook in Sweden to 2016 - Hospital Information Systems and Medical Imaging Information Systems 6Healthcare IT Market Outlook in Sweden to 2016 - Hospital Information Systems and Medical Imaging Information Systems 7Echo Therapeutics Announces Positive Results of Clinical Trial of Its Symphony® Continuous Glucose Monitoring System 2Echo Therapeutics Announces Positive Results of Clinical Trial of Its Symphony® Continuous Glucose Monitoring System 3Echo Therapeutics Announces Positive Results of Clinical Trial of Its Symphony® Continuous Glucose Monitoring System 4
The High Speed Drill handpiece is a well-balanced, high performance drill that provides high speed for,bone sculpting, along with power for difficult osteotomies. Must be used with the 6401-000 foot ...
... with hand throttle. Accepts all 1000 and ... air hose 9000-000, or existing hose with ... 9013-000, or existing hose with Linvatec/Hall connector ... existing hose with 3M connector (1000-300). , ...
Pneumatic micro sagittal saw, 30k cpm, available with various hose connector styles....
... Introducing the new large power ... function as both cordless AND electric ... Its the versatility the industry has ... the MicroAire name. Power ...
Medicine Products: