Navigation Links
Benefits of Radiation Therapy Outweigh Risks of a Second Cancer: Study
Date:3/30/2011

By Steven Reinberg
HealthDay Reporter

TUESDAY, March 29 (HealthDay News) -- The odds a second cancer will develop after radiation treatment for a first cancer are relatively low, U.S. National Cancer Institute researchers report.

In a long-term study of more than 600,000 cancer survivors, an estimated 8 percent of second cancers were attributable to radiation treatment for the original cancer, according to the study.

The results suggest that other factors, such as lifestyle risks and genetics, cause the majority of second cancers, the researchers say.

"The findings can be used by physicians to really put the risks into perspective when they are talking treatment options with their patients," said lead researcher Amy Berrington de Gonzalez, an investigator in the NCI's radiation epidemiology branch.

Patients should feel reassured, she added. "In general, the risks [of radiation therapy] are smaller than the benefits," she said.

The study, published online March 30 in The Lancet Oncology, is the first to quantify the cancer risks posed by radiation treatment for different malignancies.

Berrington de Gonzalez and colleagues collected data on 647,672 adult cancer survivors included in the U.S. Surveillance, Epidemiology and End Results cancer registries. All had survived five years or longer after cancer treatment, and follow-up ran from 1978 to 2007.

The researchers looked at outcomes for 15 different types of cancer for which radiation treatment is routine, including cancers of the rectum, larynx, lung, breast, cervix, testicles, prostate, eye and orbit, brain and thyroid.

Over the 30 years of follow-up, 9 percent of these participants developed a second cancer. Of these, about 3,300 (8 percent) might have been the result of radiation treatment, the study authors said.

Second cancers related to earlier radiation therapy varied by type, the researchers noted.

More than half of the second cancers developed in breast and prostate cancer survivors. Four percent of second cancers were in the eye, and 24 percent were cancer of the testicles, the researchers found.

Patients who had their initial cancer when young were at the greatest risk of developing a second cancer. Also at high risk were those whose organs received high doses of radiation. The likelihood of developing a secondary cancer increased over time.

When these data are put in perspective, the absolute risk for a second cancer is 3 in 1,000 over 10 years after radiation therapy and 5 in 1,000 over 15 years, Berrington de Gonzalez said.

"We know that radiation therapy can increase the risk of getting another cancer, but at the same time the benefits outweigh the risks," said Elizabeth Ward, national vice president for intramural research at the American Cancer Society.

Radiation therapy is an important and relatively safe treatment for cancer, she added.

Thanks to treatment advances, Ward said, radiologists today are better able to pinpoint treatment and limit exposure to healthy tissue than they were in the past.

Now, studies are needed to determine the cancer risks from newer radiation treatments, the authors noted.

Dr. Anthony D'Amico, chief of radiation oncology at Brigham and Women's Hospital in Boston, agreed that the NCI findings are encouraging.

"Despite people's concerns, radiation is relatively safe with regard to the issue of second cancers, because the number of cancers that result from it are very small," D'Amico said.

More information

For more information on radiation therapy, visit the U.S. National Cancer Institute.

SOURCES: Amy Berrington de Gonzalez, Ph.D., investigator, radiation epidemiology branch, U.S. National Cancer Institute, Bethesda, Md.; Anthony D'Amico, M.D., Ph.D., chief, radiation oncology, Brigham and Women's Hospital, Boston; Elizabeth Ward, Ph.D., national vice president for intramural research, American Cancer Society, Atlanta; March 30, 2011, The Lancet Oncology, online


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Alzheimers Foundation of America Applauds Social Security for Speeding Disability Benefits for Early-Onset Alzheimers Disease
2. 1Dental.com Enhances Dental Plan Benefits With New Fee Schedule
3. Freedom Healthnet Affirms Affordable Private Health Insurance Benefits
4. Surgeon General with Microsoft HealthVault Expands Consumer Benefits for the My Family Health Portrait Offering
5. DSM Personalized Nutrition Webinar Explores Benefits of Nutrition for Employee Health
6. Greenway Medical Technologies Advances Patient-Provider Benefits
7. LG Electronics Expands Benefits of Healthcare HDTVs With New Compliance Ratings at HIMSS 2010
8. Studies Detail Possible Benefits of omega-3 Fatty Acids for Dogs With Arthritis
9. New study questions benefits of elective removal of ovaries during hysterectomy
10. Health Benefits Direct Announces Extension of Expiration of Rights Offering to March 26, 2010
11. Study evaluates costs and benefits of new chemotherapy drugs
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Benefits of Radiation Therapy Outweigh Risks of a Second Cancer: Study 
(Date:6/25/2016)... ... June 25, 2016 , ... "With 30 hand-drawn hand gesture animations, ... Christina Austin - CEO of Pixel Film Studios. , ProHand Cartoon’s package transforms ... Final Cut Pro X . Simply select a ProHand generator and drag it above ...
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... On Friday, ... presented a Bronze Wellness at Work award to iHire in recognition of their exemplary ... part of the 7th annual Maryland Workplace Health & Wellness Symposium at the BWI ...
(Date:6/24/2016)... ... June 24, 2016 , ... June 19, 2016 is World Sickle ... chronic pain and the benefits of holistic treatments, Serenity Recovery Center of ... Sickle Cell Disease. , Sickle Cell Disease (SCD) is a disorder of the red ...
(Date:6/24/2016)... CA (PRWEB) , ... June 24, 2016 , ... ... is now offering micro-osteoperforation for accelerated orthodontic treatment. Dr. Cheng has extensive experience ... Damon brackets , AcceleDent, and accelerated osteogenic orthodontics. , Micro-osteoperforation is ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... ... today at the Clinical Decision Making in Emergency Medicine conference in Ponte Vedra ... authored journal articles published in Emergency Medicine Practice and Pediatric Emergency ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... ALEXANDRIA, Va. , June 24, 2016 ... a set of recommendations that would allow ... information (HCEI) with entities that make formulary and coverage ... determine the "value" of new medicines. The ... that does not appear on the drug label, a ...
(Date:6/24/2016)... 2016 Research and Markets has announced ... Diagnostic Tests" report to their offering. ... The World Market for Companion Diagnostics covers ... Market analysis in the report includes the following: ... Diagnostic Kits) by Region (N. America, EU, ROW), 2015-2020 ...
(Date:6/24/2016)... , Belgium , June ... MKT: VNRX), today announced the appointment of Dr. ... of Directors as a Non-Executive Director, effective June ... Company,s Audit, Compensation and Nominations and Governance Committees.  ... Dr. Futcher will provide independent expertise and strategic ...
Breaking Medicine Technology: