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Bench to bassinet program seeks congenital heart disease treatments
Date:3/16/2010

What: To help speed the translation of scientific discoveries into usable treatments in congenital heart disease, the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health launched the Bench to Bassinet Program (http://www.benchtobassinet.net/). This program, which involves several major research institutions across the country, will be highlighted in the March 23 edition of the Journal of the American College of Cardiology. Congenital heart disease affects the lives of 40,000 newborns a year in the United States, and up to 2 million adults are living with congenital heart disease.

The Bench to Bassinet Program consists of three major research efforts. The two newest, highlighted in the journal article, are the Pediatric Cardiac Genomic Consortium and the Cardiovascular Development Consortium. The Bench to Bassinet Program also coordinates with the NHLBI-funded Pediatric Heart Network (http://www.pediatricheartnetwork.com/), a group of academic institutions in the United States and Canada conducting research to determine optimal therapies for children with congenital and acquired heart disease. New England Research Institutes serves as the coordinating center for the overall program.

Investigators in the Pediatric Cardiac Genomics Consortium will search the human genome for genetic defects that lead to heart problems. The participating research centers will study genetic data from hundreds of individuals born with congenital heart disease to uncover genes that may cause congenital heart disease, and how those genes influence the outcome of therapy. The institutes conducting this research are: The Children's Hospital Boston and the Brigham and Women's Hospital, Mass.; The Children's Hospital of Philadelphia, Pa. ; Columbia University Health Science, New York City; the Mount Sinai School of Medicine, New York
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Contact: NHLBI Communications Office
nhlbi_news@nhlbi.nih.gov
301-496-4236
NIH/National Heart, Lung and Blood Institute
Source:Eurekalert

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