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Benaroya Research Institute receives 7-year award to lead Immune Tolerance Network
Date:1/23/2014

atments for type 1 diabetes and a myriad of other immune system and autoimmune diseases. Both Massachusetts General Hospital and the University of California, San Francisco, the previous ITN headquarters, will partner with BRI to manage ITN operations.

"This significant grant award to BRI speaks to the caliber of research being conducted in the Washington life sciences community," said Chris Rivera, president and CEO of the Washington Biotechnology and Biomedical Association. "Advancing immune tolerance solutions through the ITN adds an exciting dimension to BRI's scientific leadership and provides hope for patients fighting immune-mediated diseases through BRI's focus on accelerating research discoveries into clinical therapies."

The ITN mission is to advance knowledge and develop clinical therapies that will direct the body's immune response toward repairing tissue damage and reversing and preventing disease. The immune system plays a vital role in keeping our bodies healthy and protected from infection. However, autoimmune diseases such as type 1 diabetes, multiple sclerosis and lupus, among others, result when the immune system aberrantly attacks the body's own cells. Allergies result when the immune system overreacts to a substance that is generally harmless. Following organ or tissue transplantation, the body's immune system rejects the transplanted tissue, requiring the use of immunosuppressive drugs. In all of these examples, the ITN strategy is to re-educate the immune system to learn to stop this dangerous response, and to recognize the affected tissue as its own.

The ITN is also a leading innovator in clinical trial transparency, as well as data and sample sharing, through TrialShare, an online resource that provides access to underlying data, analyses and samples from ITN's clinical trials. The ITN TrialShare web portal addresses a critical gap in data sharing, making information available from research studies to anyone, so t
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Contact: Kay Branz
kbranz@benaroyaresearch.org
206-342-6903
Immune Tolerance Network
Source:Eurekalert

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