Navigation Links
Ben-Gurion U. researchers identify how stressed fat tissue malfunctions
Date:7/14/2009

BEER-SHEVA, ISRAEL, July 14, 2009 Ben-Gurion University of the Negev (BGU) researchers, in a collaboration with colleagues from the University of Leipzig, Germany, have identified a signaling pathway that is operational in intra-abdominal fat, the fat depot that is most strongly tied to obesity-related morbidity.

The paper was just published in the Endocrine Society's the Journal of Clinical Endocrinology and Metabolism ( J. Clin. Endocrinol. Metab. 2009; 94:2507-251)

"Fat tissue in obesity is dysfunctional, yet, the processes that cause fat tissue to malfunction are poorly understood -- specifically, it is unknown how fat cells 'translate' stresses in obesity into dysfunction," said Dr. Assaf Rudich, senior lecturer from the Department of Clinical Biochemistry at Ben-Gurion University.

Fat tissue is no longer considered simply a storage place for excess calories, but in fact is an active tissue that secretes multiple compounds, thereby communicating with other tissues, including the liver, muscles, pancreas and the brain. Normal communication is necessary for optimal metabolism and weight regulation. However, in obesity, fat (adipose) tissue becomes dysfunctional, and mis-communicates with the other tissues. This places fat tissue at a central junction in mechanisms leading to common diseases attributed to obesity, like type 2 diabetes and cardiovascular diseases.

Fat tissue dysfunction is believed to be caused by obesity-induced fat tissue stress: Cells over-grow as they store increasing amounts of fat. This excessive cell growth may cause decreased oxygen delivery into the tissue; individual cells may die (at least in mouse models), and fat tissue inflammation ensues. Also, excess nutrients (glucose, fatty acids) can also result in increased metabolic demands, and this in itself can cause cellular stress.

The BGU and Leipzig teams established a setup for collecting fat tissue samples from people un
'/>"/>

Contact: Andrew Lavin
alc@alavin.com
212-290-9540
American Associates, Ben-Gurion University of the Negev
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Gesture interface device developed by Ben-Gurion University of the Negev
2. NEJM: Low-fat diets not best for weight loss: New study by Ben-Gurion U. of the Negev
3. Ben-Gurion University of the Negev initiates project to eliminate intestinal worms in Ethiopia
4. Ben-Gurion U of the Negev study demonstrates link between appetite and elderly mortality
5. Off-label morning sickness drug deemed safe for fetuses -- Ben-Gurion U. researchers
6. Stanford researchers find culprit in aging muscles that heal poorly
7. UCLA researchers identify markers that may predict diabetes in still-healthy people
8. Mayo Clinic researchers discover new diagnostic test for detecting infection in prosthetic joints
9. Bipolar disorder relapses halved by Melbourne researchers
10. Cell that triggers symptoms in allergy attacks can also limit damage, Stanford researchers find
11. High and mighty: first common height gene identified by researchers behind obesity gene finding
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/30/2015)... 30, 2015 People from all walks of ... of meditation -- yet want a refreshingly simple and easy ... with the new app MindBody Sessions. The app can be ... http://www.mindbodysessions.com , or it can be downloaded for mobile devices ... . , Developed by MindBody Sessions LLC, the app ...
(Date:3/30/2015)... Segundo, CA (PRWEB) March 30, 2015 Corra ... tests to accommodate the needs of every industry that requires ... employers face compliance mandates or seek new ways to increase ... adding new drug panels that will help detect substance abuse ... industries have mandated drug tests,” said Corra Group Co-Founder, Gordon ...
(Date:3/30/2015)... Considered to be the best assessment tool for ... community, this next generation of the IT Audit ... data and frameworks with virtually endless possibilities. These new ... logic features are a technological force to be reckoned ... “The IT Audit Machine is just one of the ...
(Date:3/30/2015)... March 30, 2015 A new recruitment ... professionals search for their next career move. , Millions ... few years for those with skills in the booming ... http://www.1potato.com , is a jobs aggregator, pulling in opportunities ... and indexing them individually to help candidates find suitable ...
(Date:3/30/2015)... 30, 2015 TherapySites, ... mental health professionals, announced today its affiliation with ... to extend their online marketing solutions to BehaveNet ... "As we continue to see advancements in technology, ... Internet effectively in order to succeed,” said Denise ...
Breaking Medicine News(10 mins):Health News:New Web, iOS and Android App “MindBody Sessions” Makes Mindfulness and Meditation Easy 2Health News:New Web, iOS and Android App “MindBody Sessions” Makes Mindfulness and Meditation Easy 3Health News:Corra Group Adds New Employment Screening Drug Test Solutions for Clients in Every Industry 2Health News:Corra Group Adds New Employment Screening Drug Test Solutions for Clients in Every Industry 3Health News:Building on Success: Next Generation of Cyber Crime Prevention Unveiled! 2Health News:New Global Job Site Launched for Big Data and Analytics Job Seekers 2Health News:TherapySites (Websites for Therapists) Partners with BehaveNet 2
... May 8 Sunrise Senior Living, Inc. (NYSE: ... the first quarter of 2009. Sunrise will host a ... a.m. ET, to discuss the financial results."We are pleased with ... date to put the company on more solid footing," said ...
... During May,s "National Brain Tumor Awareness Month"WASHINGTON, May 8 ... the sad news of his brother,s death from a brain ... of loss -- over 200,000 people will be diagnosed with ... an effort to bring awareness and ultimately find a cure, ...
... In the 25 years between 1981 and 2006 mortality rates ... remarkable 80% in men and women aged between 25 and ... Were the health services of Iceland so much better, or ... Dr Thor Aspelund and colleagues from the Icelandic Heart Association ...
... Netherlands: New research suggests that, if used properly, vibration ... trim the particularly harmful belly fat between the organs. ... the European Congress on Obesity, scientists found that overweight ... combination with a calorie restricted diet were more successful ...
... Nicky Torres began hers earlier and, at 39, discovered she had cancer. ... this Mother,s Day, "Mommy,s fine; I,ll be here to tuck you in until ... ... and active doesn,t mean a woman isn,t at risk for breast cancer. In ...
... Teikoku Pharma USA Inc., the international specialty pharmaceutical company ... 2009; Minneapolis area based Travanti Pharma Inc., a privately ... delivery platforms that improve the safety, compliance, effectiveness and ... The Company has developed a proprietary W ...
Cached Medicine News:Health News:Sunrise Reports Financial Results for First-Quarter 2009 2Health News:Sunrise Reports Financial Results for First-Quarter 2009 3Health News:Sunrise Reports Financial Results for First-Quarter 2009 4Health News:Sunrise Reports Financial Results for First-Quarter 2009 5Health News:Sunrise Reports Financial Results for First-Quarter 2009 6Health News:Sunrise Reports Financial Results for First-Quarter 2009 7Health News:Sunrise Reports Financial Results for First-Quarter 2009 8Health News:Sunrise Reports Financial Results for First-Quarter 2009 9Health News:Sunrise Reports Financial Results for First-Quarter 2009 10Health News:Sunrise Reports Financial Results for First-Quarter 2009 11Health News:Sunrise Reports Financial Results for First-Quarter 2009 12Health News:Sunrise Reports Financial Results for First-Quarter 2009 13Health News:Sunrise Reports Financial Results for First-Quarter 2009 14Health News:Sunrise Reports Financial Results for First-Quarter 2009 15Health News:Sunrise Reports Financial Results for First-Quarter 2009 16Health News:Sunrise Reports Financial Results for First-Quarter 2009 17Health News:Sunrise Reports Financial Results for First-Quarter 2009 18Health News:Sunrise Reports Financial Results for First-Quarter 2009 19Health News:Sunrise Reports Financial Results for First-Quarter 2009 20Health News:Grey Ribbon Crusade(TM) Promotes National Unification in the Fight Against Brain Tumors 2Health News:Massive decline in rates of coronary death in Iceland are largely attributed to risk factor reductions in the population 2Health News:Study: Vibration plate machines may aid weight loss and trim abdominal fat 2Health News:Study: Vibration plate machines may aid weight loss and trim abdominal fat 3Health News:Mom Offers Personal Mother's Day Message on Importance of Annual Mammograms 2Health News:Teikoku Pharma USA Acquires Travanti Pharma Inc. 2
(Date:3/30/2015)...  Cochlear Corporation Vice President of U.S. Sales ... join Valencia Technologies ( www.valenciatechnologies.com ) and his ... who is the CEO of Valencia.  Schloffman will ... be responsible for generating enthusiasm and support for ... coin-sized neuromodulation device in the treatment of resistant ...
(Date:3/30/2015)...  Edelberg & Associates (EA) and ScribeAmerica today ... medical coding software platform designed to engage and ... coder at the point of care.  In a ... has successfully built, deployed and tested a new ... and medical coder that can radically improve natural ...
(Date:3/30/2015)... 30, 2015  New York College of Health Professions ... Properties portfolio with U.S. Patent #8,996,098 donated by its ... represents a surgical instrument that allows surgeons to view ... were in the traditional format of a slide that ... databases during surgery, thus providing the surgeon real time ...
Breaking Medicine Technology:Cochlear VP of U.S. Sales Jerry Schloffman Accepts Chief of Market Development Position at Valencia Technologies 2Edelberg & Associates and ScribeAmerica Partner to Launch Healthcare Industry's First Ever Real-time Medical Coding Solution 2Edelberg & Associates and ScribeAmerica Partner to Launch Healthcare Industry's First Ever Real-time Medical Coding Solution 3World Renowned Inventor Continues To Break Boundaries With Latest Patent 2World Renowned Inventor Continues To Break Boundaries With Latest Patent 3
Bend with "H" Shaped Tip, LEFT; in Titanium....
Lightly Curved-Blunt Tips Rounded Blades; 1mm Eye in Blades; 27mm from mid screw to tip. Matte finish; Stainless Steel, overall length 120mm...
... Catheter is indicated for balloon ... of a coronary artery or ... purpose of improving myocardial perfusion. ... also designed to provide distal ...
16mm from Mid-screw to Tips, blunt tips; overall length 110mm; Stainless Steel...
Medicine Products: