Navigation Links
Belly 'Membrane' May Regulate Immune System, Mouse Study Finds

THURSDAY, June 7 (HealthDay News) -- A fatty membrane in the belly long believed to serve little purpose may actually play an important role in immune system regulation, according to a new study using mouse cells.

The finding might one day lead to new drugs for organ-transplant patients and people with autoimmune diseases such as lupus and Crohn's disease, said the researchers, from the Loyola University Chicago Stritch School of Medicine.

The membrane, called omentum, lines the abdominal cavity and covers most abdominal organs; it also is a repository for fat tissue. In lab experiments with cells from mice, the researchers found that omentum cells appear to secrete a substance that can reduce the activity of the immune system.

The study was published June 6 in the journal PLoS One.

"We now have evidence that the omentum is not just fat sitting in the belly," the study's corresponding author, Makio Iwashima, an associate professor in the microbiology and immunology department, said in a university news release.

The finding could aid the development of new drugs that would suppress the immune system with fewer side effects than the current drugs used to treat organ-transplant patients and people with autoimmune diseases, in which the immune system attacks the body, the researchers said.

The researchers also found that the omentum contains a type of stem cell that travels to the site of an injury and helps regenerate tissue.

Research involving animals should be considered preliminary because the results often don't have implications for humans.

More information

The U.S. National Institute of Arthritis and Musculoskeletal and Skin Diseases has more about autoimmune diseases.

-- Robert Preidt

SOURCES: Loyola University Health System, news release, June 6, 2012

Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Unusual protein helps regulate key cell communication pathway
2. First study to suggest that the immune system may protect against Alzheimers changes in humans
3. Reactions to HIV drug have autoimmune cause, reports AIDS journal
4. Babies susceptibility to colds linked to immune response at birth
5. Scientists study serious immune malfunction
6. Rutgers team discovers novel approach to stimulate immune cells
7. Mayo Clinic: Exhaustion renders immune cells less effective in cancer treatment
8. Regulatory immune cell diversity tempers autoimmunity in rheumatoid arthritis
9. How does the immune system fight off threats to the brain? New research yields fresh insight
10. Block its recycling system, and cancer kicks the can, according to new Penn study
11. Its Not Just What You Eat, Its When You Eat, Mouse Study Finds
Post Your Comments:
Related Image:
Belly 'Membrane' May Regulate Immune System, Mouse Study Finds
(Date:10/13/2017)... ... October 13, 2017 , ... While it’s often important ... problem. Fortunately, an inventor from Austin, Texas, has identified a solution. , She developed ... darkness or restricted lighting. As such, it eliminates the need to turn on a ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... Hannah Randall, PharmD ‘17, and Jennifer Huggins, PharmD ’17, along with clinical ... the primary prevention of cardiovascular diseases during the 15th Annual Women’s Health ...
(Date:10/13/2017)... RIDGE, N.J. (PRWEB) , ... October 13, 2017 , ... ... annual Holly Day Market. Featuring a collection of specialty vendors and unique items from ... of personalized and quality-focused health and wellness services offered by the VNA. The ...
(Date:10/13/2017)... ... October 13, 2017 , ... Talented host, ... lowdown on sciatica in a new episode of "Success Files," which is an ... and innovation and investigates each subject in-depth with passion and integrity. , Sciatica ...
(Date:10/12/2017)... ... October 12, 2017 , ... First Healthcare Compliance ... management, will showcase a range of technology and learning solutions at the 68th ... and Expo to be held October 14–18, 2017 at the Mandalay Bay Resort ...
Breaking Medicine News(10 mins):
(Date:10/5/2017)... 2017  In response to the nationwide opioid ... Surgeons (AAOMS) released prescribing recommendations that urge ibuprofen ... as a first-line therapy to manage a patient,s ... Recognizing the value and importance of ... Prescribing: Acute and Postoperative Pain Management" stresses that ...
(Date:10/4/2017)... 4, 2017 OBP Medical , ... medical devices, today announced regulatory approval from ... (or Agência Nacional de Vigilância Sanitária (ANVISA)) to ... surgical retractor with integrated LED light source and ... and exposure of a tissue pocket or cavity ...
(Date:10/2/2017)...  AllianceRx Walgreens Prime, the combined central specialty pharmacy ... benefit manager Prime Therapeutics LLC (Prime), today officially began ... unveiling of new signage at its headquarters in ... a few other company-owned facilities across the country. This ... of whom will begin to see the AllianceRx Walgreens ...
Breaking Medicine Technology: