Navigation Links
BellBrook Labs Webinar: Development of Ectonucleotidase Assay Methods Using the Transcreener® HTS Assay Platform
Date:5/11/2017

Join us for a webinar on Tuesday, May 23 at 11:00 AM CDT: Development of Ectonucleotidase Assay Methods Using the Transcreener® HTS Assay Platform

Register for the Free Webinar

Ectonucleotidases are plasma membrane-bound enzymes with externally oriented active sites that metabolize nucleotides to nucleosides. One example is ectonucleoside triphosphate diphosphohydrolase-1, also known as CD39, ENTPD1, or NTPDase1. CD39 hydrolyzes ATP and ADP to AMP. Other ectonucleotidases such as CD73 process the AMP further into adenosine, which is an important signaling molecule for immunosuppression in the tumor microenvironment. For this reason, ectonucleotidases are emerging as promising immuno-oncology targets, with a number of groups working on small molecule and antibody-based inhibitors. As the only HTS method capable of direct detection of nucleotides, the Transcreener® platform is uniquely suited for measuring ectonucleotidase activity with the high sensitivity and low levels of interference required for a successful HTS campaign.

In this webinar we will discuss:

  • Assay development for CD39 using the Transcreener® AMP/GMP Assay with fluorescence polarization and TR-FRET readouts
  • Demonstrated assay robustness for use in high-throughput screening
  • Inhibitor potency profiling for CD39
  • Recent external publications using Transcreener® HTS assays for studying ectonucleotidase activity

Register for the Free Webinar

After registering, you will receive a confirmation e-mail containing more information about joining the webinar on May 23rd.

About BellBrook Labs:

BellBrook Labs is dedicated to accelerating drug discovery and biological research by providing innovative high throughput screening solutions. Transcreener® is a universal, homogeneous biochemical assay platform based on detection of nucleotides that makes it easy to screen thousands of different enzymes. These include validated targets like kinases, as well as emerging targets like ATPases, GTPases, methyltransferases, and glycosyltransferases. Detection reagents and drug discovery services from BellBrook Labs help researchers progress toward more effective therapies for cancer and other debilitating diseases.

Read the full story at http://www.prweb.com/releases/Ectonucleotidase/Assay/prweb14321785.htm.


'/>"/>
Source: PRWeb
Copyright©2017 Vocus, Inc.
All rights reserved


Related medicine news :

1. Webinar: Comparing Prices in Group Health vs. Workers' Compensation
2. Register to Join the Merrill DataSite's Webinar: Avoiding the Post-Merger Blues: How to Reduce the Risk of Post-deal Disputes
3. Join Merrill DataSite's Webinar: Best Practices for Strategic Growth - Where to Invest in the Maturing U.S. Economy
4. Webinar: Comparing Payments for Hospital and Professional Services for Injured Workers across States and the Impact of Reforms
5. Webinar: How to Use Online Reviews to Get More Leads
6. Webinar: WCRI and Brandeis University Discuss Opioids
7. Edifecs to Host a Webinar: Preparing for 2015 Open Enrollment - Map Your Path to Readiness
8. Zane Benefits Announces New Webinar: “5 HR Data Points Every Small Business Should Track (with Calculations)”
9. Latest vRad Webinar: Building World-Class Breast Imaging Services Virtually Anywhere with Telemedicine Best Practices
10. Zane Benefits Announces New Webinar: “Can Tax-Free Premium Reimbursement Work for You?”
11. Zane Benefits Announces Upcoming Webinar: How to Adapt and Grow with the ACA [A Case Study with Josiah Allis]
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/10/2019)... ... , ... AltMed Florida , one of the fastest growing Medical Marijuana ... opening of its second MÜV™ Medical Cannabis Dispensary on the First Coast – scheduled ... Beach. , Located at Beach Plaza Shopping Center at the corner of Beach Boulevard ...
(Date:10/8/2019)... SAUSALITO, Calif. (PRWEB) , ... October 08, 2019 ... ... 2,100 stores - Kroger, Ralphs, QFC and Fred Meyer, King Sooper, Fry’s, Roundy’s, ... Paleo, Whole30 approved, dairy-free, grain-free & gluten-free. , “Ingredient purity and fresh ...
(Date:10/8/2019)... , ... October 08, 2019 , ... Dr. Amir HagShenas ... in San Jose, CA experience relief from this common and treatable condition. Dr. HagShenas’ ... to save adults from living with uncomfortable symptoms, including tender and bleeding gums, and ...
(Date:10/8/2019)... ... October 08, 2019 , ... PotentiaMetrics, an Austin, ... Henderson as Chief Medical Officer. Dr. Henderson will be responsible for the development ... Henderson previously served as Chair of both the Informatics Governance and the Inpatient ...
(Date:10/8/2019)... ... October 08, 2019 , ... Smile Brands Inc. has ... compensation monitoring site, Comparably. Smile Brands, a leading dental support organization with nearly 440 ... mission to deliver Smiles for Everyone®. The Happiness Award is the latest in a ...
Breaking Medicine News(10 mins):
(Date:10/19/2019)... ... October 18, 2019 , ... A new study conducted ... adalimumab use in pregnancy was not associated with an increased risk for adverse ... The findings were published today in the Public Library of Science ...
(Date:10/17/2019)... ... October 17, 2019 , ... Mount ... deadly pediatric nerve cancer, who would otherwise have no treatment options, according to ... of the most common and aggressive pediatric nervous system tumors and generally has ...
(Date:10/17/2019)... ... October 17, 2019 , ... The findings of a new study ... individuals studied could be caused by toxic chemicals rather than the inhalation of oily ... With E-Cigarette Use (Vaping): A Report of Eight Cases ,” by Sanjay Mukhopadhyay, MD, ...
Breaking Medicine Technology: