Navigation Links
Belatacept after a kidney transplant: Minor added benefit for certain patients
Date:11/9/2012

Belatacept (trade name Nulojix) has been approved since June 2011 to prevent a rejection reaction of the body to the donor organ (transplant) in adults who have received a kidney transplant. The Institute for Quality and Efficiency in Health Care (IQWiG) has examined the added benefit of the drug pursuant to the "Act on the Reform of the Market for Medicinal Products" (AMNOG).

The assessment showed an indication of a minor added benefit of belatacept in adults with transplants from donors who had been selected according to the so-called standard criteria. Serious side effects such as urinary tract infections or pneumonia occurred less frequently in these patients and they also discontinued treatment due to side effects less often.

In patients who received transplants from donors who had been selected according to extended criteria (in this case, only deceased donors, who could also have been older and could have had certain accompanying diseases), no relevant differences could be found between the treatment with belatacept or with the comparator therapy, cyclosporine A. That means an added benefit of belatacept is not proven for these patients.

Belatacept in comparison with cyclosporine A

The immunosuppressant belatacept suppresses the immune system and thereby the natural defence reaction of the body to foreign tissue. Immunosuppressive drugs have to be taken long-term after a transplant in order to prevent the donor kidney being rejected after transplantation.

The appropriate comparator therapy used for the early benefit assessment was cyclosporine A. Both belatacept and cyclosporine A are given in combination with corticosteroids and a mycophenolic acid. Belatacept is given as an infusion (intravenously) into the bloodstream, whereas cyclosporine A is administered as a tablet.

Different donor characteristics

In both of the studies that were part of the approval of the drug and
'/>"/>

Contact: Dr. Anna-Sabine Ernst
presse@iqwig.de
0049-221-356-85153
Institute for Quality and Efficiency in Health Care
Source:Eurekalert

0

GOOD

Page: 1 2 3

Related medicine news :

1. Young girls more likely to report side effects after HPV vaccine
2. Experts Offer Advice After Yankee Pitchers Trampoline Injury
3. Breast cancer patients suffer treatment-related side effects long after completing care
4. Codeine After Surgery Could Endanger Certain Kids: Study
5. Drug May Prevent Pancreatitis After Digestive Procedure
6. Diagnostic yield of colonoscopy for melena after nondiagnostic upper endoscopy is lower than previously reported
7. After Hospitalization, Men More Likely to Show Up in ER
8. Men More Prone to Complications After Brain, Spine Surgery
9. Close Laundry Detergent Right After Use, Expert Says
10. Donor Kidney Re-Used in Second Patient After Failing in First
11. Guidelines say diet, exercise, weight control improve odds after cancer diagnosis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/19/2013)... FL (PRWEB) May 19, 2013 Exciting ... ®, who is reintroducing a great practice known through ... Brushing, also known as dry body brushing, has so ... Heshelow, founder of Sublime Beauty®. "We love that circulation ... of our largest organ, the skin, is supported through ...
(Date:5/19/2013)... May 19, 2013 Beginning Wednesday, May 29 ... Blood Center (RRVBC) will feature “Hot Dog Wednesdays" and Ice ... RRVBC will provide hot dogs and all the fixin's to ... each day throughout the summer. “Donors are our lifeline. The ... stable and adequate blood supply. This is a small ...
(Date:5/19/2013)... The AMTC team will be screening local ... Convention & Trade Center on June 1st. Professionals and amateurs, ... are free of charge. , Actors, Models and Talent for ... successful artists and grads like Caitlin Kinney - SYTYCD, ... Chris Young - on his Liquid Neon 2013 Tour, Taylor ...
(Date:5/19/2013)... (PRWEB) May 19, 2013 Minor fender ... the road that require parties to the accident to ... for Disease Control and Prevention (CDC) data from 2010, ... of death (i). In fact, in 2005, ... year. Additionally, more than 2.3 million drivers and ...
(Date:5/19/2013)... 2013 The Da Vinci robot lawyers ... in the nation’s first trial involving a Da Vinci ... State Superior Court, was filed by the widow of ... complications in a robot-assisted prostate removal, according to a ... robotic surgery lawsuit alleges those complication’s hastened his ...
Breaking Medicine News(10 mins):Health News:Exciting New Skin Brushes at Sublime Beauty® Bring Health and Beauty Benefits; Celebrities and Models Know the Secret 2Health News:Hot Dog Wednesdays and Ice Cold Slushies Return to Rock River Valley Blood Center for the Summer 2Health News:Actors, Models and Talent for Christ Hosting Auditions in Columbus, GA June 1st in Search of Local Talent 2Health News:Auto Accident Infographic Issued by d’Oliveira & Associates on Steps to Take After a Car Crash 2Health News:Da Vinci Surgical Robot Lawyers at Wright & Schulte LLC Note Recent Developments in Da Vinci Robot Lawsuit Trial 2Health News:Da Vinci Surgical Robot Lawyers at Wright & Schulte LLC Note Recent Developments in Da Vinci Robot Lawsuit Trial 3Health News:Da Vinci Surgical Robot Lawyers at Wright & Schulte LLC Note Recent Developments in Da Vinci Robot Lawsuit Trial 4
... The most common indication worldwide for pediatric transplantation, biliary ... liver disease in newborns. Recently, Childrens Hospital of Pittsburgh ... children with biliary atresia face that lead to the ... of children undergoing their first liver transplant are diagnosed ...
... Washington University School of Medicine in St. Louis have ... proteins associated with the formation of actin networks, which ... to move is important to a broad range of ... disease-causing invaders and how metastasizing cancer cells migrate from ...
... What: , The AACR Annual Meeting features the ... cancer research. This years meeting focuses on ... pipeline, clinical trials, and new approaches to cancer ... of the meeting, the program schedule and related ...
... Workout ... Jude Children,s Research ... Hospital(R), FORT LAUDERDALE, Fla., Jan. 8 ... Ab Crunch Challenge,a fitness challenge that will benefit your waistline and is expected ...
... Pa., Jan. 8 Isolagen(TM), Inc. (Amex: ILE ... Declan Daly,Chief Executive Officer of Isolagen, will present at ... 2008 at 2:00 p.m.,(Pacific Time) / 11:00 a.m. (Eastern ... Francis Hotel in San Francisco, California., The presentation ...
... Top Five New York State Hospitals, ... (OTC Bulletin Board: GLOB), an international e-Health, ... Wyndgate,Technologies(R) division has signed a purchase agreement ... New York for its,advanced transfusion management software, ...
Cached Medicine News:Health News:Children's Hospital physicians publish review of transplant issues in patients with biliary atresia 2Health News:Insights into cell movement likely to aid immune study, cancer research 2Health News:Insights into cell movement likely to aid immune study, cancer research 3Health News:Get a Six Pack While Giving Back 2Health News:Get a Six Pack While Giving Back 3Health News:Isolagen Inc. to Present at the 26th Annual JPMorgan Healthcare Conference 2Health News:Global Med Technologies(R) Adds Eighth SafeTrace Tx(R) Client in New York State 2Health News:Global Med Technologies(R) Adds Eighth SafeTrace Tx(R) Client in New York State 3
(Date:5/16/2013)... SYDNEY , May 16, 2013  HeartWare International, Inc. ... innovator of less invasive, miniaturized circulatory support technologies that are ... CEO Doug Godshall is scheduled to ... a.m. EDT on Monday, May 20, 2013.  The conference is ... Hotel. A live webcast of the Company,s presentation ...
(Date:5/16/2013)... , May 16, 2013  Amgen (NASDAQ: AMGN ... on Tuesday, May 21, 2013, at the Sheraton New York ... beginning at 10:00 a.m. Eastern Daylight Time. Joseph ... Research and Development at Amgen, will present at the conference. ... Events Calendar on Amgen,s website, www.amgen.com , under Investors. ...
(Date:5/16/2013)... , May 16, 2013 ... in the U.S. to access the widely-used OrthoView digital ... PC and Internet connection to get started. ... software for over 10 years, is dedicated to enabling ... with digital x-ray images, when printed film is unavailable. ...
Breaking Medicine Technology:HeartWare Presentation At The 2013 UBS Global Healthcare Conference To Be Webcast 2OrthoView Announces the U.S. Launch of a New, Subscription-based, Digital Planning and Templating Solution for Individual Orthopaedic Surgeons 2
... 2011 Sharp HealthCare,s affiliated medical groups -- Sharp ... Elite Status, the highest possible designation for quality care ... as part of its 2011 Standards of Excellence program. ... of managed care physician groups. "We are ...
... Healthcare Partners , a strategic private equity firm focused ... it has completed a sale and recapitalization of CareCentrix, ... is the nation,s leading provider of home health benefits ... sold its majority interest in CareCentrix to Summit Partners. ...
Cached Medicine Technology:Sharp HealthCare Medical Groups Recognized for "Elite" Care 2Sharp HealthCare Medical Groups Recognized for "Elite" Care 3Water Street Healthcare Partners Completes Sale and Recapitalization of CareCentrix 2Water Street Healthcare Partners Completes Sale and Recapitalization of CareCentrix 3
These handy dispensers save space and organize gloves in labs and next to hand washers. Clear acrylic. Many other sizes and custom configurations available....
Single side double clamp knife holder for the Vibratome 8000...
... The Starter Package is ... up your laboratory. The package ... accessory kit, additional mounting blocks, ... head, and a rotating stage ...
... Package is a solid solution ... The package includes the Vibratome ... mounting blocks, v-block adapter, specimen ... rotating stage assembly for ease ...
Medicine Products: