Navigation Links
Being an MRSA carrier increases risk of infection and death

Patients harboring methicillin-resistant Staphylococcus aureus (MRSA) for long periods of time continue to be at increased risk of MRSA infection and death, according to a new study in the July 15 issue of Clinical Infectious Diseases, currently available online.

MRSA is an antibiotic-resistant bacterium that can cause a variety of serious infections. The bacterium most commonly colonizes the nostrils, although it can be found in other body sites. Most research has focused on people who are newly colonized by the bacteria and has found that they are at substantial risk of subsequent infections. The new study shows that the increased risk of infection continues, with almost a quarter of MRSA-colonized patients developing infections after a year or more has passed since the colonization was confirmed. The infections include pneumonia and bloodstream events, and some infections were linked to deaths.

"Since infection risk remains substantial among long-term carriers of MRSA, these patients should be targeted for interventions to reduce subsequent risk of infection along with patients who newly acquire MRSA," said author Susan Huang, MD, MPH.

The researchers built on their previous work in this area, which showed that one-third of new MRSA carriers in a large tertiary care medical center developed infections within the year following the first detection of colonization. But, as, Dr. Huang points out, "risks beyond the first year of carriage were largely unknown."

In this study, Dr. Huang and coauthor Rupak Datta, MPH, followed 281 patients who had been MRSA-positive for at least one year and some for more than four years. Of these, 23 percent developed an MRSA infection within the year-long duration of this study. Pneumonia was the most common infection. MRSA was identified as a contributor to the deaths of 14 of the patients.

In their paper, the authors suggest that the MRSA infection risk may be more closely tied to a hospitalization event than to the duration of carriage: "We submit that these high risks of MRSA infection among culture-positive prevalent carriers are not only preferentially detected because of hospitalization, but may in fact be incurred because of device related, wound related, and immunologic declines associated with a current illness."

"One explanation for this may be that patients who have surgical wounds or intravenous lines may allow MRSA a route of entry and invasion that would not otherwise exist," added Dr. Huang.

The authors caution that because this study was performed in a large tertiary care medical center, they may have studied a disproportionate number of critically ill patients who could be at a relatively higher risk for infection. The results may not be generalizable to all patient settings.


Contact: Steve Baragona
Infectious Diseases Society of America

Related medicine news :

1. Effects of healing touch therapy being studied
2. Feeling fat is worse than being it
3. Photo: Minding Your Childs Health: A Passport to Your Childs Well Being; A Ticket to Your Peace of Mind
4. Thinking About Being a Father?
5. Teenagers and young adults with cancer can face long delays before finally being diagnosed
6. Young patient waited ten months before being diagnosed with cancer
7. Being Born Small, Early Raises Autism Risk
8. Ozone-Depleting Inhalers Being Phased Out
9. Scientists image a single HIV particle being born
10. AIDS Action Urges Everyone to Help End the AIDS Epidemic by Being Part of the Search for an HIV Vaccine
11. Nominations for Outstanding Cancer Survivor Award Being Accepted by Karmanos Cancer Institute Through April 27
Post Your Comments:
(Date:11/27/2015)... Los Angeles, CA (PRWEB) , ... November 27, 2015 , ... ... new study carried out by the University of Toronto and the University of British ... number of hospitalizations for head injuries. The article explains that part of the reason ...
(Date:11/27/2015)... ... November 27, 2015 , ... An ... way to dispense prescription medications at home, so he invented the patent-pending ELECTRONIC ... and dispense prescription medications. In doing so, it could help to prevent potential ...
(Date:11/27/2015)... ... November 27, 2015 , ... ProSidebar: Fashion is a set ... With ProSidebar: Fasion, video editors can easily add an informative sidebar to any ... opener. Utilize presets featuring self-animating drop zones, lines, bars, and text with the ...
(Date:11/27/2015)... ... November 27, 2015 , ... A simply groundbreaking television series, "Voices in America", ... delves into an array of issues that are presently affecting Americans. Dedicated to providing ... this show is changing the subjects consumers focus on, one episode at a time. ...
(Date:11/27/2015)... ... November 27, 2015 , ... The men and ... nonprofit healthcare organizations in the country. They have overseen financial turnarounds, shown commitment ... advance the healthcare industry as a whole through their advocacy and professional efforts. ...
Breaking Medicine News(10 mins):
(Date:11/25/2015)... ) ... "Global Brain Monitoring Devices Market 2015-2019" ... ) has announced the addition of ... 2015-2019" report to their offering. ... ) has announced the addition of the ...
(Date:11/25/2015)...  Linden Care, LLC, a retail specialty pharmacy focused ... suffering from chronic pain, said today that it is ... (TRO) enjoining Express Scripts from unilaterally terminating the Pharmacy ... --> --> The company said that ... --> --> In ...
(Date:11/25/2015)...  Henry Schein, Inc., the world,s largest provider of ... and animal health practitioners, will unveil at the Greater ... ConnectDental® Pavilion , which brings together for the first ... to help any practice or laboratory enter the digital ... schedule of experts appearing at the Pavilion. --> ...
Breaking Medicine Technology: