Navigation Links
Being an MRSA carrier increases risk of infection and death

Patients harboring methicillin-resistant Staphylococcus aureus (MRSA) for long periods of time continue to be at increased risk of MRSA infection and death, according to a new study in the July 15 issue of Clinical Infectious Diseases, currently available online.

MRSA is an antibiotic-resistant bacterium that can cause a variety of serious infections. The bacterium most commonly colonizes the nostrils, although it can be found in other body sites. Most research has focused on people who are newly colonized by the bacteria and has found that they are at substantial risk of subsequent infections. The new study shows that the increased risk of infection continues, with almost a quarter of MRSA-colonized patients developing infections after a year or more has passed since the colonization was confirmed. The infections include pneumonia and bloodstream events, and some infections were linked to deaths.

"Since infection risk remains substantial among long-term carriers of MRSA, these patients should be targeted for interventions to reduce subsequent risk of infection along with patients who newly acquire MRSA," said author Susan Huang, MD, MPH.

The researchers built on their previous work in this area, which showed that one-third of new MRSA carriers in a large tertiary care medical center developed infections within the year following the first detection of colonization. But, as, Dr. Huang points out, "risks beyond the first year of carriage were largely unknown."

In this study, Dr. Huang and coauthor Rupak Datta, MPH, followed 281 patients who had been MRSA-positive for at least one year and some for more than four years. Of these, 23 percent developed an MRSA infection within the year-long duration of this study. Pneumonia was the most common infection. MRSA was identified as a contributor to the deaths of 14 of the patients.

In their paper, the authors suggest that the MRSA infection risk may be more closely tied to a hospitalization event than to the duration of carriage: "We submit that these high risks of MRSA infection among culture-positive prevalent carriers are not only preferentially detected because of hospitalization, but may in fact be incurred because of device related, wound related, and immunologic declines associated with a current illness."

"One explanation for this may be that patients who have surgical wounds or intravenous lines may allow MRSA a route of entry and invasion that would not otherwise exist," added Dr. Huang.

The authors caution that because this study was performed in a large tertiary care medical center, they may have studied a disproportionate number of critically ill patients who could be at a relatively higher risk for infection. The results may not be generalizable to all patient settings.


Contact: Steve Baragona
Infectious Diseases Society of America

Related medicine news :

1. Effects of healing touch therapy being studied
2. Feeling fat is worse than being it
3. Photo: Minding Your Childs Health: A Passport to Your Childs Well Being; A Ticket to Your Peace of Mind
4. Thinking About Being a Father?
5. Teenagers and young adults with cancer can face long delays before finally being diagnosed
6. Young patient waited ten months before being diagnosed with cancer
7. Being Born Small, Early Raises Autism Risk
8. Ozone-Depleting Inhalers Being Phased Out
9. Scientists image a single HIV particle being born
10. AIDS Action Urges Everyone to Help End the AIDS Epidemic by Being Part of the Search for an HIV Vaccine
11. Nominations for Outstanding Cancer Survivor Award Being Accepted by Karmanos Cancer Institute Through April 27
Post Your Comments:
(Date:10/13/2017)... ... October 13, 2017 , ... “The Journey: From the Mountains ... possible to save lost souls in the Philippines. “The Journey: From the Mountains to ... dedicated teacher of the Bible. She has taught all ages and currently teaches a ...
(Date:10/12/2017)... LA (PRWEB) , ... October 12, 2017 , ... Planet ... in the U.S., announced today its plans to open a flagship location in Covington, ... occupy the former Rooms To Go store next to Office Depot in the Holiday ...
(Date:10/12/2017)... ... ... Asante, a nationally recognized health system in southern Oregon, ... health joint venture through an agreement, effective October 1, 2017, to create AccentCare ... company with Asante, delivering clinically integrated care, for the past eight years. This ...
(Date:10/12/2017)... ... 2017 , ... Leading pediatric oncology experts at Children’s National Health System ... Congress of the International Society of Paediatric Oncology (SIOP) Oct. 12-15. Chaired by ... and Blood Disorders at Children’s National, and Stephen P. Hunger, M.D., Chief of ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... in property taxes a year. In some states—like New York, New Jersey, Massachusetts, ... contrast, many overseas retirement havens have extremely low property-tax rates, which contributes to ...
Breaking Medicine News(10 mins):
(Date:10/11/2017)... 2017  Hill-Rom Holdings, Inc. ("Hill-Rom") (NYSE: HRC), today ... Las Piedras, Puerto Rico , where ... Following a comprehensive ... minor structural damage, temporary loss of power and minimal ... completed, manufacturing operations have resumed, and the company expects ...
(Date:10/7/2017)... , Oct. 6, 2017   Provista, ... more than $100 billion in purchasing power, today announced ... and information. The Newsroom is the online ... industry trends, infographics, expert bios, news releases, slideshows and ... access to a wealth of resources at their fingertips, ...
(Date:10/4/2017)... Oct. 4, 2017  According to the Centers for Disease Control and ... October . PhysicianOne Urgent Care is helping communities across Massachusetts ... , by offering no-cost* flu shots through the end of the ... certain health insurance regulations. ... time to get a flu shot is by the end of October, ...
Breaking Medicine Technology: