Navigation Links
Beer Drinking May Speed Pancreatic Cancer Onset
Date:5/21/2008

Other alcohol also boosted the risk, as did smoking, study found

WEDNESDAY, May 21 (HealthDay News) -- Heavy smoking and drinking, especially beer, may hasten the onset of pancreatic cancer, according to researchers who presented their data Tuesday at the Digestive Disease Week 2008 conference in San Diego.

Beer appears to exert a stronger influence than hard liquor or wine in lowering the age of onset of pancreatic cancer, said researcher Dr. Michelle A. Anderson, assistant professor of medicine at the University of Michigan.

Anderson and her colleagues evaluated patients from The Pancreatic Cancer Collaborative Registry, a multi-center, international patient registry, looking at whether the patients drank or smoked, and if so, how much and what type of liquor.

They evaluated the smoking and drinking (or abstinence) patterns of 453 patients in all, about equal numbers of men and women.

Patients who smoked did tend to develop pancreatic disease at a younger age and there were dose-related effects, Anderson said. Heavy smokers (such as those who have smoked more than a pack a day for 40 years, or more than two packs for 20 years) presented with pancreatic cancer an average of seven years before nonsmokers.

The average age of onset of pancreatic cancer is between 70 to 80, experts noted.

Heavy drinkers, defined as having more than three daily drinks, presented with pancreatic cancer 10 years younger than those who did not drink.

Comparing beer, wine and hard liquor, the team found that beer lowered the age of developing pancreatic cancer most, Anderson said. When she compared beer drinkers to non-beer drinkers, the effect was statistically significant; however, when she considered other variables that may affect cancer onset, the effect disappeared.

Cigarette smoking is already a well-known risk factor for pancreatic cancer. Heavy alcohol intake may induce chronic inflammatory changes that are also linked with cancer, Anderson said.

The combination of chronic smoking plus drinking had no stronger effect on pancreatic risk than either habit alone, the researchers found.

Pancreatic cancer is expected to be diagnosed in nearly 38,000 people in the United States this year, according to the American Cancer Society, and about 34,000 will die of the disease. The lifetime risk is about 1 in 79 but is affected by factors such as advancing age, obesity and family history.

Because it is often emerges without symptoms, pancreatic cancer is often not detected until its later stages, when treatment is less effective. But even if caught at stage one the outlook is bleak, researchers said. At stage one, the 5-year survival from pancreatic malignancy is about 33 percent.

The pancreas, about 6 inches long and less than 2 inches wide, extends across the abdomen. It makes key hormones, including insulin, and helps to balance blood sugar.

Finding pancreatic tumors earlier -- especially important for people with a family history, or other factor indicating high risk -- is the focus of much research. And a new study suggests that combining two methods may provide better screening, according to another researcher, Dr. Richard Zubarik, associate professor of medicine and chief of endoscopy at Fletcher Allen Health Care in Burlington, Vt.

His research team used a blood test called CA19-9 -- a test to detect a tumor marker most often used to monitor disease progress and predict survival rates. They then combined that screen with an endoscopic ultrasound to try to detect the cancer in the earliest stages.

Of the 272 patients enrolled, one patient was diagnosed with pancreatic cancer and one with abnormal pancreatic cell growth.

However, the method is expensive -- it cost $14,000 to detect the cancer and about $11,000 to detect the abnormal cell growth, Zubarik said.

Other strategies are being studied to see if they can increase the bleak survival rates. In another study, researchers compared the records of more than 4,000 patients with pancreatic cancer and divided them into two groups -- those who had the ultrasound (about 12 percent of the sample) and those who did not.

Those who received the ultrasound at diagnosis had a somewhat longer average survival time, said Dr. Ananya Das, associate chair of medicine, Mayo Clinic in Scottsdale, Ariz. Undergoing this screen increased average survival time for patients from 5 months to 9 months.

Going to a center that offers this method may mean that patients receive better overall care, he said. Endoscopic ultrasound is available at leading medical centers, he said.

In patients at very high risk of pancreatic cancer, such as those with a family history, surveillance performed by a team of specialists can also help, said Dr. Teresa A. Brentnall, associate professor of medicine at the University of Washington, Seattle.

"Our goal is to protect them from pancreatic cancer," she said. Her team found that two tests could help. One is the endoscopic ultrasound, the other is called an endoscopic retrograde cholangiopancreatography.

Brentnall's team followed 100 patients using these methods. Of the 100 patients, two developed cancer (one inoperable), and 20 had abnormal cell growths. The combination can help lead to detection of pancreatic pre-cancer, she said.

More information

To learn more about pancreatic cancer, visit the American Cancer Society.



SOURCES: press conference, May 20, 2008, Digestive Disease Week, San Diego, with: Michelle A. Anderson, M.D., assistant professor of medicine, University of Michigan, Ann Arbor; Teresa A. Brentnall, M.D., associate professor of medicine, division of gastroenterology, University of Washington, Seattle; Ananya Das, M.D., associate chair of medicine, Mayo Clinic, Scottsdale, Ariz; Richard Zubarik, M.D., associate professor of medicine and chief of endoscopy, Fletcher Allen Health Center, University of Vermont Dartmouth-Hitchcock Medical Center, Lebanon, N.H.


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Heavy Drinking Boosts Stroke Risk for Chinese Men
2. Good Cholesterol Wont Help Heavy-Drinking Older Men
3. Drinking Often Spurs Move to Poorer Neighborhoods
4. Underage drinking starts before adolescence
5. Briefing on a new Web resource to address global drinking water crisis
6. Family history of alcoholism affects response to drug used to treat heavy drinking
7. Teenage Drinking Can Spell Lasting Trouble
8. Alcohol and cancer: is drinking the new smoking?
9. Kids still not drinking enough milk
10. Parents Encouraged to Set an Example for Their Teens and Help Stop Underage Drinking
11. Morrison Takes Aim at Underage Drinking in New Radio Campaign
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Beer Drinking May Speed Pancreatic Cancer Onset
(Date:5/31/2016)... ... May 31, 2016 , ... To ... solutions to the healthcare industry, The University of Scranton is adding a Certificate ... path to a career in rapidly growing field of healthcare information. , ...
(Date:5/30/2016)... ... May 30, 2016 , ... As the CDC relaxes its ... and their efforts to keep their households lice free. , According to a ... new policies that keep kids in the classroom despite the fact that they may ...
(Date:5/30/2016)... ... 30, 2016 , ... Shaolin Institute officially starts the annual ... intensive summer training camp starts on June 17th on Shaolin Institute Atlanta Campus. ... a fun and unique experience with an opportunity to learn KungFu martial arts ...
(Date:5/29/2016)... ... May 29, 2016 , ... Whole Health Supply is happy to announce ... clipper is available to the public. This is an unusual clipper because it opens ... average clipper. , Everything about this product is concentrated on ease of use, functionality ...
(Date:5/28/2016)... Aliso Viejo, California (PRWEB) , ... May 28, 2016 , ... ... just need to drag and drop a preset onto their media," said Christina Austin ... from Pixel Film Studios, editors can quickly and easily add stylish color grades to ...
Breaking Medicine News(10 mins):
(Date:5/27/2016)... 2016 According to the 2016 ... driving ambulatory blood pressure monitoring system market growth. With ... ability to respond to different pressure rates, leading to ... to various cardiovascular disorders such as heart failure, stroke, ... are growing in prevalence each year. WHO estimates that ...
(Date:5/26/2016)... May 26, 2016 According to a ... Management Market - U.S. Industry Analysis, Size, Share, Growth, Trends, ... in the U.S. was valued at US$ 5.89 Bn in ... 3.4% from 2015 to 2023 to reach US$ 7.99 Bn ... current and emerging needle free drug delivery devices and the ...
(Date:5/25/2016)... -- FDA 510(k) clearance covers Confocal ... urological and surgical applications Mauna Kea ... the multidisciplinary confocal laser endomicroscopy (CLE) platform, today ... with the 12 th 510(k) clearance from ... new FDA clearance covers Confocal Miniprobes indicated for ...
Breaking Medicine Technology: