Navigation Links
Bedside assessment may provide better outcomes for older cancer patients
Date:10/26/2011

WINSTON-SALEM, N.C. -- In geriatric medicine, the adage that age is just a number holds true. New research from Wake Forest Baptist Medical Center uses a simple assessment tool to determine how well older adults diagnosed with acute myelogenous leukemia (AML) can handle treatment.

"We're trying to develop better assessment strategies for older adults with this particularly aggressive disease because, functionally, they encompass a broad age spectrum," said Heidi D. Klepin, M.D., M.S., of Wake Forest Baptist and the study's lead author. "It's well known that older patients with acute leukemia do not tolerate and benefit from standard, aggressive therapies as much as younger patients. However, certain older individuals can clearly benefit from aggressive treatment. We know we need to treat their cancer, but can we individualize the treatment to each patient and get them through their cancer treatment in better shape?"

Most treatment recommendations are based on chronological age stratification, said Klepin, an assistant professor of internal medicine, hematology/oncology. Research has importantly focused on how to better treat the tumor, but there has been little focus on the individual patient as a whole to quantify how functional they are across the board to withstand the aggressive treatment, she added.

For Klepin, this means looking beyond the patient's chronological age. "You're 70, but what kind of a 70-year-old are you? Are you a very functional 70-year-old and pass all these assessments with flying colors?" she said. "Then you should be treated like a 55-year-old. But if you're a frail 70-year-old, we need to take that into consideration and figure out ways to get you through the treatment better or consider alternative treatment strategies that can be better tolerated."

The study, published in this month's issue of the Journal of the American Geriatrics Society, looked at whether a bedside geriatric assessment (GA) can be a useful tool to evaluate cognitive function, psychological state, physical function and co-morbid disease to identify those patients most vulnerable to the side effects of AML chemotherapy. This is the first study to evaluate the feasibility of performing a comprehensive GA among newly diagnosed older adults with AML to provide better, more individualized treatment.

The study was conducted at Wake Forest Baptist over an 18-month period and involved 61 patients; the mean age was 70.8. Klepin said that as a group, these patients presented with depressive symptoms, distress and physical function impairments and had more difficulty with mobility tasks. The simple questionnaires and functional tests done as part of this assessment picked up symptoms and impairments that standard oncology assessments do not routinely identify, she explained.

"Ultimately, information gained from a geriatric assessment could help optimize therapeutic decision making and clinical outcomes for older adults with AML," said Klepin. "Our hope is to take this assessment and streamline it so any nurse can administer it at the bedside and give the clinician more information about that patient than they would have had before. This will help so we can get them through their treatments in the best shape possible."


'/>"/>
Contact: Bonnie Davis
bdavis@wakehealth.edu
336-716-4977
Wake Forest Baptist Medical Center
Source:Eurekalert

Related medicine news :

1. Oridion and Masimo Sign Distribution Agreement to Sell Capnostream™20 Bedside Monitors with the Masimo Patient SafetyNet™ System
2. Taking the final step from the bench to the hospital or clinic bedside
3. Hospital Caregivers use MagnaSnap Paper Clamps at Bedside to Improve Patient Satisfaction Scores
4. Better imaging from bench to bedside
5. Bedside ultrasound becomes a reality
6. Simple new bedside screening effectively identifies patients with acute aortic dissection
7. ATS, ERS issue official standards for the quantitative assessment of lung structure
8. Agility Consulting Partners with pan (Performance Assessment Network) to Bring Custom Private Label Assessment Capability to Human Resource Professionals and Consultants
9. Bick Group Launches Cloud Computing Quick Assessment Program (CCQA)
10. World's First Mobile Application for Alzheimer's Disease Risk Assessment
11. Association of fiber and colorectal cancer risk differs depending on dietary assessment method
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... ... Mohebi Hair Restoration, has recently contributed a medical article to the newly revamped ... cosmetictown.com. Dr. Mohebi’s article spotlights the hair transplant procedure known as Follicular ...
(Date:10/12/2017)... ... ... Leading pediatric oncology experts at Children’s National Health System will ... the International Society of Paediatric Oncology (SIOP) Oct. 12-15. Chaired by Jeffrey ... Disorders at Children’s National, and Stephen P. Hunger, M.D., Chief of the Division ...
(Date:10/12/2017)... ... October 12, 2017 , ... Women-owned and Grand Rapids-based ... and Brightest in Wellness® by Best and Brightest. OnSite Wellness will be honored ... 20 from 7:30 a.m. to 2 p.m. at the Henry Autograph Collection Hotel, ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... in property taxes a year. In some states—like New York, New Jersey, Massachusetts, ... contrast, many overseas retirement havens have extremely low property-tax rates, which contributes to ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... of California Berkeley, and other leading institutions in announcing the launch of the ... to change the way animals are raised for food. , Founding members of ...
Breaking Medicine News(10 mins):
(Date:10/11/2017)... Texas , Oct. 11, 2017  True ... services, has amplified its effort during National Breast ... about hereditary cancer risks. ... of Clinical Oncology calculated that more than 10 ... have inherited mutations in BRCA1 or BRCA2 and have ...
(Date:10/5/2017)... , Oct. 5, 2017  In response ... of Oral and Maxillofacial Surgeons (AAOMS) released prescribing ... – to be used as a first-line therapy ... Recognizing the ... AAOMS White Paper "Opioid Prescribing: Acute and Postoperative ...
(Date:10/2/2017)... INDIANAPOLIS , Oct. 2, 2017  Eli Lilly ... its financial results for the third quarter of 2017 ... a conference call on that day with the investment ... performance. The conference call will begin at ... public can access a live webcast of the conference ...
Breaking Medicine Technology: