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Beauty and grooming science evolves
Date:2/15/2009

or foundation formulations to eliminate the problems of pasty or orange look on skin.

Genomics of Skin Aging

Genomic Analysis of the Anti-oxidant Capacity of Aging Skin, Presented by Rosemarie Osborne, PhD

Studies have established that environmental factors, such as UV light, trigger skin damage and photo-aging. And while the benefits of antioxidants in offsetting this damage have been documented, thorough understanding of skin's anti-oxidant response element (ARE) on a genomic level are key to the next generation of targeted prevention and reversal strategies. To uncover these insights, researchers analyzed gene expression patterns in sun-exposed and sun-protected old and young skin. The study results detail the genomic patterns found, including a pathway which found older, exposed skin having a dysregulated expression of ARE-related proteins, thus resulting in reduced defenses against oxidative damage, as compared to younger skin.

Stratum Corneum Lipid Metabolism Pathways Associated with Intrinsic and Extrinsic Aging, Presented by Rosemarie Osborne, PhD

The same genomic study described above found new insights on the stratum corneum, the skin's barrier layer responsible for protecting against environmental assaults. Through a separate analysis, P&G Beauty & Grooming researchers gleaned vital genomic understandings of the respective roles of intrinsic and extrinsic aging in affecting the stratum corneum's ability to perform its core function. The same study analyzed this affect while adding the variable of a topical cosmetic compound, using human skin equivalents. The results demonstrated that the compound increased the expression of genes involved in lipid biosynthesis and metabolism of the stratum corneum, leading to new appreciation of its potential in improving barrier maintenance and repair.

Hair Science

Liquid Crystals for Surface Modifications of Colored Hair, Presented by Steve Shiel, Ph
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Contact: Lauren Harris
lharris@spectrumscience.com
214-773-6644
Spectrum Science Public Relations
Source:Eurekalert

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