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Beating a Global Killer: HIV/AIDS
Date:4/1/2009

GLENDALE, Calif., April 1 /PRNewswire-FirstCall/ -- Immunotech Laboratories, Inc.

Immunotech Laboratories announces successful Participation in DART conference in Puerto Rico with its abstract "Irreversible Pepsin Fraction (IPF) displays significant antiretroviral activity via specific novel cytokine stimulation in vitro investigation of activity on human lymphocytes."

Additionally, Immunotech will present at the 5th European Conference on Clinical and Social Research on AIDS and Drugs, with its abstract titled "IPF displays significant Antiviral activity in vitro without provoking the presentation of resistant profiles of minority subspecies."

H. Zhabilov (1), M. Selbovitz, D. Miller (2), J. Gibbs

(1) Immunotech Laboratories, California, USA, (2) AIDS Institute, New York, USA

Background

Resistance to all commercially available antiretroviral (ARV) agents within all classes has been reported. The occurrence of multi-class resistance remains high, with 20% of infected individuals developing resistance to two or more classes within six years of initiating treatment, and 10% of newly diagnosed infections already resistant to at least one class in the U.S. Multi-class resistance is even more prevalent in disenfranchised patient populations, whose rates of successful adherence to even the most simplified regimens available remains prohibitively low.

IPF, like other natural autoantibody based fractionated proteins, has an affinity to pathogenic binding and simultaneously produces effects of immune homeostasis in the presence of replacativly competent HIV. IPF has shown significant antiretroviral activity via immune stimulatory pathways in vitro, notably helper Th-1 cells elaborate cytokines INFy, IL-2. These cells selectively promote cell-mediated immune responses that are disadvantageous to viral replication with selection
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SOURCE Immunotech Laboratories, Inc.
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